thioacetanilide

ethanethioamide, N-phenyl-

CAS: 637-53-6 C8 H9 N S MW: 151.23173000

Identification

Namethioacetanilide
IUPACN-phenylethanethioamide
CAS Number637-53-6
EINECS211-288-4
FDA UNIIL9AL2GO03Y
Molecular FormulaC8 H9 N S
Molecular Weight151.23173000
MDL NumberMFCD00004942
Nikkaji NumberJ6.915I
Beilstein2205727
XlogP31.70 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 76.00 °C. @ 760.00 mm Hg
Boiling Point 225.10 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.014000 mmHg (est)
Flash Point 194.00 °F. TCC ( 89.90 °C. ) (est)
logP (o/w) 1.710
Soluble in water, 2596 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantioxidants

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-guinea pig LD50 1775 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryantioxidants
Recommendation for thioacetanilide usage levels up tonot for fragrance use.
Recommendation for thioacetanilide flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

ethanethioamide, N-phenyl- N- phenyl thioacetamide 1-( phenylamino)ethane-1-thione N- phenylethanethioamide N- phenylethanthioamid N- phenylthioacetamide PubMed: Arylazolylthioacetanilide. Part 11: design, synthesis and biological evaluation of 1,2,4-triazole thioacetanilide derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. PubMed: Arylazolyl(azinyl)thioacetanilides. Part 10: design, synthesis and biological evaluation of novel substituted imidazopyridinylthioacetanilides as potent HIV-1 inhibitors. PubMed: Arylazolyl(azinyl)thioacetanilide. Part 9: Synthesis and biological investigation of thiazolylthioacetamides derivatives as a novel class of potential antiviral agents. PubMed: 1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 inhibitors. PubMed: 1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation. PubMed: Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. PubMed: Application of beta-(2-chloroaroyl)thioacetanilide in synthesis(III): an efficient three-component synthesis of thiochromeno[2,3-b]pyridines catalyzed by KF/neutral Al2O3 co-operated with PEG 6000 under microwave irradiation. PubMed: 1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors. PubMed: Thioacetanilide at 120 K. PubMed: Application of beta-(2-chloroaroyl) thioacetanilides in synthesis: an unusual and highly efficient access to thiochromeno[2,3-b]pyridine derivatives. PubMed: Synthesis and biological evaluation of new 3-substituted indole derivatives as potential anti-inflammatory and analgesic agents. PubMed: Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant. PubMed: Synthesis, anticonvulsant, and anti-inflammatory evaluation of some new benzotriazole and benzofuran-based heterocycles. PubMed: Correlation analyses for bimolecular nucleophilic substitution reactions of chloroacetanilide herbicides and their structural analogs with environmentally relevant nucleophiles. PubMed: Optical analysis of the cirrhotic liver by near-infrared time-resolved spectroscopy. PubMed: [Substantiation of maximum permissible levels of thioacylanilide in the air of work areas]. PubMed: The metabolism of thioacetanilide in the rat. PubMed: Determination of some organic thio-compounds by precipitation of mercuric sulphide from mercury(II) ammine complexes-I Determination of thioacetamide and thioacetanilide.