thioacetanilide
ethanethioamide, N-phenyl-
Identification
| Name | thioacetanilide |
| IUPAC | N-phenylethanethioamide |
| CAS Number | 637-53-6 |
| EINECS | 211-288-4 |
| FDA UNII | L9AL2GO03Y |
| Molecular Formula | C8 H9 N S |
| Molecular Weight | 151.23173000 |
| MDL Number | MFCD00004942 |
| Nikkaji Number | J6.915I |
| Beilstein | 2205727 |
| XlogP3 | 1.70 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 76.00 °C. @ 760.00 mm Hg |
| Boiling Point | 225.10 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.014000 mmHg (est) |
| Flash Point | 194.00 °F. TCC ( 89.90 °C. ) (est) |
| logP (o/w) | 1.710 |
| Soluble in | water, 2596 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-guinea pig LD50 1775 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | antioxidants |
| Recommendation for thioacetanilide usage levels up to | not for fragrance use. |
| Recommendation for thioacetanilide flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
ethanethioamide, N-phenyl-
N-
phenyl thioacetamide
1-(
phenylamino)ethane-1-thione
N-
phenylethanethioamide
N-
phenylethanthioamid
N-
phenylthioacetamide
PubMed:
Arylazolylthioacetanilide. Part 11: design, synthesis and biological evaluation of 1,2,4-triazole thioacetanilide derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
PubMed:
Arylazolyl(azinyl)thioacetanilides. Part 10: design, synthesis and biological evaluation of novel substituted imidazopyridinylthioacetanilides as potent HIV-1 inhibitors.
PubMed:
Arylazolyl(azinyl)thioacetanilide. Part 9: Synthesis and biological investigation of thiazolylthioacetamides derivatives as a novel class of potential antiviral agents.
PubMed:
1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 inhibitors.
PubMed:
1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation.
PubMed:
Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
PubMed:
Application of beta-(2-chloroaroyl)thioacetanilide in synthesis(III): an efficient three-component synthesis of thiochromeno[2,3-b]pyridines catalyzed by KF/neutral Al2O3 co-operated with PEG 6000 under microwave irradiation.
PubMed:
1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
PubMed:
Thioacetanilide at 120 K.
PubMed:
Application of beta-(2-chloroaroyl) thioacetanilides in synthesis: an unusual and highly efficient access to thiochromeno[2,3-b]pyridine derivatives.
PubMed:
Synthesis and biological evaluation of new 3-substituted indole derivatives as potential anti-inflammatory and analgesic agents.
PubMed:
Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant.
PubMed:
Synthesis, anticonvulsant, and anti-inflammatory evaluation of some new benzotriazole and benzofuran-based heterocycles.
PubMed:
Correlation analyses for bimolecular nucleophilic substitution reactions of chloroacetanilide herbicides and their structural analogs with environmentally relevant nucleophiles.
PubMed:
Optical analysis of the cirrhotic liver by near-infrared time-resolved spectroscopy.
PubMed:
[Substantiation of maximum permissible levels of thioacylanilide in the air of work areas].
PubMed:
The metabolism of thioacetanilide in the rat.
PubMed:
Determination of some organic thio-compounds by precipitation of mercuric sulphide from mercury(II) ammine complexes-I Determination of thioacetamide and thioacetanilide.