tranexamic acid

cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-

CAS: 1197-18-8 C8 H15 N O2 MW: 157.21295000

Identification

Nametranexamic acid
IUPAC4-(aminomethyl)cyclohexane-1-carboxylic acid
CAS Number1197-18-8
EINECS214-818-2
FDA UNII6T84R30KC1
Molecular FormulaC8 H15 N O2
Molecular Weight157.21295000
MDL NumberMFCD00001466
Nikkaji NumberJ3.664A
Beilstein2207452

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 2.5e+004 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesastringents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-chicken LD50 > 10000 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 5310 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryastringents
Recommendation for tranexamic acid usage levels up tonot for fragrance use.
Recommendation for tranexamic acid flavor usage levels up tonot for flavor use.

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We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

amikapron trans-4-( aminomethyl)cyclohexane carboxylic acid 4-( aminomethyl)cyclohexane-1-carboxylic acid trans-4-( aminomethyl)cyclohexanecarboxylic acid trans-p-( aminomethyl)cyclohexanecarboxylic acid trans-4- aminomethylcyclohexane-1-carboxylic acid trans-1- aminomethylcyclohexane-4-carboxylic acid anvitoff carxamin cyclocapron cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans- cyklokapron emorhalt exacyl frenolyse hexapromin hexatron lysteda mastop retavase rikavarin rikavarin-S spiramin tamcha tranex transamin transamlon trasamlon ugurol PubMed: Design of the Study of Tranexamic Acid during Air Medical Prehospital Transport (STAAMP) Trial: Addressing the Knowledge Gaps. PubMed: Recurrent angio-oedema--three cases of C1 inhibitor deficiency. PubMed: Transmural intestinal wall permeability in severe ischemia after enteral protease inhibition. PubMed: Development of SPME method for concomitant sample preparation of rocuronium bromide and tranexamic acid in plasma. PubMed: Tranexamic acid induces kaolin intake stimulating a pathway involving tachykinin neurokinin 1 receptors in rats. PubMed: Lifestyle and dietary influences on nosebleed severity in hereditary hemorrhagic telangiectasia. PubMed: Review of recently approved alternatives to anticoagulation with warfarin for emergency clinicians. PubMed: Treatment of heavy menstrual bleeding with the estradiol valerate and dienogest oral contraceptive pill. PubMed: Drug, devices, technologies, and techniques for blood management in minimally invasive and conventional cardiothoracic surgery: a consensus statement from the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) 2011. PubMed: Coronary artery bypass grafting after aprotinin: are we doing better? PubMed: Tranexamic acid: a new option for heavy menstrual bleeding. PubMed: Oral modified-release tranexamic acid for heavy menstrual bleeding. PubMed: Modified hydrotalcite-like compounds as active fillers of biodegradable polymers for drug release and food packaging applications. PubMed: Evaluation and management of abnormal uterine bleeding in premenopausal women. PubMed: Use of a novel technique, solid phase microextraction, to measure tranexamic acid in patients undergoing cardiac surgery. PubMed: Pharmacokinetic studies in women of 2 novel oral formulations of tranexamic acid therapy for heavy menstrual bleeding. PubMed: The use of antifibrinolytic agents in spine surgery. A meta-analysis. PubMed: Review and application of serine protease inhibition in coronary artery bypass graft surgery. PubMed: [Hereditary angioedema in the German-speaking region]. PubMed: Tranexamic acid in the treatment of hereditary angioedema. PubMed: Lack of efficacy of tranexamic acid in thrombocytopenic bleeding. PubMed: Cronkhite-canada syndrome associated with gastric cancer: report of a case. PubMed: Pharmacokinetics and bioavailability of tranexamic acid.