hydroxyproline
L-proline, 4-hydroxy-, (4S)-
Identification
| Name | hydroxyproline |
| IUPAC | (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid |
| CAS Number | 51-35-4 |
| EINECS | 200-091-9 |
| FDA UNII | RMB44WO89X |
| Molecular Formula | C5 H9 N O3 |
| Molecular Weight | 131.13133000 |
| MDL Number | MFCD00064320 |
| Nikkaji Number | J191.775G |
| Beilstein | 081441 |
Regulatory
| FDA Mainterm (SATF) | 51-35-4 ; L-HYDROXYPROLINE |
Physical Properties
| Appearance | white powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 274.00 °C. @ 760.00 mm Hg |
| Boiling Point | 355.00 to 356.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000001 mmHg @ 25.00 °C. (est) |
| Flash Point | 336.00 °F. TCC ( 168.60 °C. ) (est) |
| logP (o/w) | -0.350 (est) |
| Soluble in | water, 361000 mg/L @ 25 °C (exp) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antistatic agents |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | special dietary and nutritional additives |
| Recommendation for hydroxyproline usage levels up to | not for fragrance use. |
| Recommendation for hydroxyproline flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(2S,4S)-(-)-4-
hydroxy-2-pyrrolidinecarboxylic acid
(2S,4S)-4-
hydroxy-2-pyrrolidinecarboxylic acid
(4S)-4-
hydroxy-L-prolin
(4S)-4-
hydroxy-L-proline
trans-4-
hydroxy-laevo-proline
L-
hydroxyproline
L-4-
hydroxyproline
laevo-4-
hydroxyproline
(2S,4S)-(-)-4-
hydroxypyrrolidine-2-carboxylic acid
(2S,4S)-4-
hydroxypyrrolidine-2-carboxylic acid
L-
proline, 4-hydroxy-, (4S)-
J-Stage:
Increasing Effect of an Oral Intake of L-Hydroxyproline on the Soluble Collagen Content of Skin and Collagen Fragments in Rat Serum