tripropylene glycol
propanol, ((1-methyl-1,2-ethanediyl)bis(oxy))bis-
Identification
| Name | tripropylene glycol |
| IUPAC | 2-[2-(2-hydroxypropoxy)propoxy]propan-1-ol |
| CAS Number | 24800-44-0 |
| EINECS | 246-466-0 |
| FDA UNII | 3C8845E7C1 |
| Molecular Formula | C9 H20 O4 |
| Molecular Weight | 192.25520000 |
| MDL Number | MFCD00014405 |
| Nikkaji Number | J47.851B |
| Beilstein | 2235421 |
| XlogP3 | -0.40 (est) |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | FCN 1071 |
| DG SANTE Food Contact Materials | tripropyleneglycol |
| FDA Mainterm (IAUFC) | 24800-44-0 ; TRIPROPYLENE GLYCOL |
Physical Properties
| Appearance | colorless to pale yellow clear liquid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 1.01700 to 1.02200 @ 20.00 °C. |
| Pounds per Gallon - (est). | 8.472 to 8.514 |
| Refractive Index | 1.44200 to 1.44700 @ 20.00 °C. |
| Boiling Point | 271.00 °C. @ 760.00 mm Hg |
| Vapor Density | 6.63 ( Air = 1 ) |
| Flash Point | > 230.00 °F. TCC ( > 110.00 °C. ) |
| logP (o/w) | -0.586 (est) |
| Soluble in | water, 1.269e+005 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-rat LD50 3000 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | emulsifiers, humectants |
| Recommendation for tripropylene glycol usage levels up to | not for fragrance use. |
| Recommendation for tripropylene glycol flavor usage levels up to | not for flavor use. |
Potential Uses
Natural Occurrence
Synonyms
2-(2-(2-
hydroxypropoxy)propoxy)-1-propanol
2-[2-(2-
hydroxypropoxy)propoxy]propan-1-ol
((1-
methyl-1,2-ethanediyl)bis(oxy))bispropanol
propanol, ((1-methyl-1,2-ethanediyl)bis(oxy))bis-
1-
propanol, 2-[2-(2-hydroxypropoxy)propoxy]-
tri(propylene glycol)
1,4,7-
trimethyl-3,6-dioxaoctane-1,8-diol
tripropyleneglycol
PubMed:
Synthesis of Fullerene-Fused Dioxanes/Dioxepanes: Ferric Perchlorate-Mediated One-Step Reaction of [60]Fullerene with Diols.
PubMed:
Photoswitchable hydrogel surface topographies by polymerisation-induced diffusion.
PubMed:
A toxicological review of the propylene glycols.
PubMed:
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
PubMed:
Shear and dielectric responses of propylene carbonate, tripropylene glycol, and a mixture of two secondary amides.
PubMed:
Dermal penetration of propylene glycols: measured absorption across human abdominal skin in vitro and comparison with a QSAR model.
PubMed:
Effects of water contamination on the supercooled dynamics of a hydrogen-bonded model glass former.
PubMed:
Polymerization of electric field-centered double emulsion droplets to create polyacrylate shells.
PubMed:
Electrochemical sensor for parabens based on molecular imprinting polymers with dual-templates.
PubMed:
Final report on the safety assessment of PPG-2 methyl ether, PPG-3 methyl ether, and PPG-2 methyl ether acetate.
PubMed:
Paramagnetic ultrasmall gadolinium oxide nanoparticles as advanced T1 MRI contrast agent: account for large longitudinal relaxivity, optimal particle diameter, and in vivo T1 MR images.
PubMed:
A novel polyurethane-based root canal-obturation material and urethane-acrylate-based root canal sealer-part 2: evaluation of push-out bond strengths.
PubMed:
A novel polyurethane-based root canal-obturation material and urethane acrylate-based root canal sealer--part I: synthesis and evaluation of mechanical and thermal properties.
PubMed:
Bio-oxidation of tripropylene glycol under aerobic conditions.
PubMed:
Dielectric secondary relaxations in polypropylene glycols.
PubMed:
Water dynamics in n-propylene glycol aqueous solutions.
PubMed:
Dielectric and shear mechanical alpha and beta relaxations in seven glass-forming liquids.
PubMed:
Dielectric relaxation processes in water mixtures of tripropylene glycol.
PubMed:
Soot emissions from spherical droplet flames for mixtures of JP8 and tripropylene glycol monomethyl ether.
PubMed:
Minimal model for Beta relaxation in viscous liquids.
PubMed:
Biodegradation of potential diesel oxygenate additives: dibutyl maleate (DBM), and tripropylene glycol methyl ether (TGME).
PubMed:
Binding efficiency and transport properties of molecularly imprinted polymer thin films.
PubMed:
A method for measuring dermal exposure to multifunctional acrylates.
PubMed:
Comparative in vitro cytotoxicity of ethyl acrylate and tripropylene glycol diacrylate to normal human skin and lung cells.
PubMed:
A tape-stripping method for measuring dermal exposure to multifunctional acrylates.
PubMed:
Workers' dermal exposure to UV-curable acrylates in the furniture and Parquet industry.
PubMed:
Occupational dermatitis to ultraviolet-cured acrylic-based inks in computer hard disc manufacturing.
PubMed:
Tripropylene glycol diacrylate but not ethyl acrylate induces skin tumors in a twenty-week short-term tumorigenesis study in Tg.AC (v-Ha-ras) mice.
PubMed:
Absence of systemic in vivo genotoxicity after dermal exposure to ethyl acrylate and tripropylene glycol diacrylate in Tg.AC (v-Ha-ras) mice.
PubMed:
Occupational allergic contact dermatitis caused by photobonded sculptured nails and a review of (meth) acrylates in nail cosmetics.
PubMed:
Occupational allergic contact dermatitis caused by epoxy diacrylate in ultraviolet-light-cured paint, and bisphenol A in dental composite resin.
PubMed:
Lemna minor membranes affected by adjuvants.
PubMed:
Allergic contact dermatitis due to an amino-substituted diacrylate in a UV-cured lacquer.
PubMed:
Allergic contact dermatitis to ultra violet cured inks.
PubMed:
The sensitizing capacity of multifunctional acrylates in the guinea pig.
PubMed:
The pharmacology of the mono methyl ethers of mono-, di-, and tripropylene glycol in the dog with observations on the auricular fibrillation produced by these compounds.