triethyl phosphate

phosphoric acid, triethyl ester

CAS: 78-40-0 C6 H15 O4 P MW: 182.15611200

Identification

Nametriethyl phosphate
IUPACtriethyl phosphate
CAS Number78-40-0
EINECS201-114-5
FDA UNIIQIH4K96K7J
Molecular FormulaC6 H15 O4 P
Molecular Weight182.15611200
MDL NumberMFCD00009077
Nikkaji NumberJ2.406F
Beilstein1705772
XlogP30.80 (est)

Regulatory

FDA Mainterm (IAUFC)78-40-0 ; TRIETHYL PHOSPHATE

Physical Properties

Appearance colorless clear liquid (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.06700 to 1.07200 @ 20.00 °C.
Pounds per Gallon - (est). 8.889 to 8.931
Refractive Index 1.40370 @ 25.00 °C.
Melting Point -56.00 °C. @ 760.00 mm Hg
Boiling Point 208.00 to 209.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.177000 mmHg @ 25.00 °C. (est)
Vapor Density 6.28 ( Air = 1 )
Flash Point 210.00 °F. TCC ( 99.00 °C. )
logP (o/w) 0.800
Soluble in water, 500000 mg/L @ 25 °C (exp)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usessolvents

Organoleptic Properties

Odor Description mild cider

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-rat LD50 1165 mg/kg
Dermal Toxicityskin-guinea pig LD50 > 20 ml/kg
Inhalation Toxicityinhalation-mouse LC > 44300 ug/m3/4

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorysolvents
Recommendation for triethyl phosphate usage levels up tonot for fragrance use.
Recommendation for triethyl phosphate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

phosphoric acid triethyl ester o- phosphoric acid triethyl ester phosphoric acid, triethyl ester triethoxyphosphine oxide triethylphosphate PubMed: Occurrence and risk assessment of organophosphate esters in drinking water from Eastern China. PubMed: Growth and alkaline phosphatase activity of Chattonella marina and Heterosigma akashiwo in response to phosphorus limitation. PubMed: Sonochemical precipitation of amorphous uranium phosphates from trialkyl phosphate solutions and their thermal conversion to UP2O7. PubMed: Desorption electrospray ionization-mass spectrometric analysis of low vapor pressure chemical particulates collected from a surface. PubMed: Tris(2-butoxyethyl)phosphate and triethyl phosphate alter embryonic development, hepatic mRNA expression, thyroid hormone levels, and circulating bile acid concentrations in chicken embryos. PubMed: Characterization and nanomechanical properties of novel dental implant coatings containing copper decorated-carbon nanotubes. PubMed: High-separation efficiency micro-fabricated multi-capillary gas chromatographic columns for simulants of the nerve agents and blister agents. PubMed: Dispersive liquid-liquid microextraction combined with ultrahigh performance liquid chromatography/tandem mass spectrometry for determination of organophosphate esters in aqueous samples. PubMed: Microwave-assisted extraction combined with gel permeation chromatography and silica gel cleanup followed by gas chromatography-mass spectrometry for the determination of organophosphorus flame retardants and plasticizers in biological samples. PubMed: Uptake and translocation of organophosphates and other emerging contaminants in food and forage crops. PubMed: Investigations of chemical warfare agents and toxic industrial compounds with proton-transfer-reaction mass spectrometry for a real-time threat monitoring scenario. PubMed: History of arsenic ethers: who was Felix D'Arcet? PubMed: Adsorption of trimethyl phosphate and triethyl phosphate on dry and water pre-covered hematite, maghemite, and goethite nanoparticles. PubMed: Application of PM-IRRAS to study thin films on industrial and environmental samples. PubMed: DFT investigations of phosphotriesters hydrolysis in aqueous solution: a model for DNA single strand scission induced by N-nitrosoureas. PubMed: Benzene removal by a novel modification of enhanced anaerobic biostimulation. PubMed: Non-contact detection of chemical warfare simulant triethyl phosphate using PM-IRRAS. PubMed: Bioactive silica-based drug delivery systems containing doxorubicin hydrochloride: in vitro studies. PubMed: Occurrence and fate of organophosphorus flame retardants and plasticizers in coastal and marine surface waters. PubMed: Dust as a collection media for contaminant source attribution. PubMed: Infrared multiple photon dissociation action spectroscopy and theoretical studies of triethyl phosphate complexes: effects of protonation and sodium cationization on structure. PubMed: Volatile constituents, inorganic elements and primary screening of bioactivity of black coral cigarette holders. PubMed: Analytical developments and preliminary assessment of human exposure to organophosphate flame retardants from indoor dust. PubMed: Gas-phase synchrotron FTIR spectroscopy of weakly volatile alkyl phosphonate and alkyl phosphate compounds: vibrational and conformational analysis in the terahertz/far-IR spectral domain. PubMed: Mechanical properties and in vitro bioactivity of Ca5(PO4)2SiO4 bioceramic. PubMed: History of organophosphate synthesis: the very early days. PubMed: Crystallographically engineered, hydrothermally crystallized hydroxyapatite films: an in vitro study of bioactivity. PubMed: History of methyl phosphoric esters: Hall, Weger, and Lossen. PubMed: Plasma chemical degradation of phosphorous-containing warfare agents simulants. PubMed: In vitro apatite formation on organic-inorganic hybrids in the CaO-SiO(2)-PO (5/2)-poly(tetramethylene oxide) system. PubMed: Modeling metal cation-phosphate interactions in nucleic acids: activated dissociation of Mg+, Al+, Cu+, and Zn+ complexes of triethyl phosphate. PubMed: Optofluidic ring resonator sensors for rapid DNT vapor detection. PubMed: The synthesis of some perhydrobenzimidazolinium salts and their application in pd-carbene catalyzed heck and suzuki reactions. PubMed: The effects of chronic inorganic and organic phosphate exposure on bactericidal activity of the coelomic fluid of the sea urchin Lytechinus variegatus (Lamarck) (Echinodermata: Echinoidea). PubMed: The synthesis of phosphor ethers: who was Franz Anton Voegeli? PubMed: Genotoxicity studies of a desealant solvent mixture, SR-51. PubMed: Synthesis of high purity hydroxyapatite nanopowder via sol-gel combustion process. PubMed: Oil red-O stains non-adipogenic cells: a precautionary note. PubMed: Characterization and utilization of a novel triflate ionic liquid stationary phase for use in comprehensive two-dimensional gas chromatography. PubMed: Gas-phase vibrational spectroscopy and ab initio study of organophosphorus compounds: discrimination between species and conformers. PubMed: Rate constants for the gas-phase reactions of OH radicals with dimethyl phosphonate over the temperature range of 278-351 K and for a series of other organophosphorus compounds at approximately 280 K. PubMed: Modeling metal cation-phosphate interactions in nucleic acids in the gas phase via alkali metal cation-triethyl phosphate complexes. PubMed: Multi-encoded rugate porous silicon as nerve agents sensors. PubMed: Development of a thermal evaporation cell for gas-phase infrared absorption spectroscopy of compounds with low volatility. PubMed: Detection of chemical weapon agents and simulants using chemical ionization reaction time-of-flight mass spectrometry. PubMed: Effects of triethyl phosphate and nitrate on electrokinetically enhanced biodegradation of diesel in low permeability soils. PubMed: Activation of the binuclear metal center through formation of phosphotriesterase-inhibitor complexes. PubMed: Kinetic and product study of the gas-phase reactions of OH radicals, NO(3) radicals, and O(3) with (C(2)H(5)O)(2)P(S)CH(3) and (C(2)H(5)O)(3)PS. PubMed: Synthesis of ordered mesoporous zirconium phosphate films by spin coating and vapor treatments. PubMed: Atmospheric chemistry of diethyl methylphosphonate, diethyl ethylphosphonate, and triethyl phosphate. PubMed: Temperature-dependent rate constants for the gas-phase reactions of OH radicals with 1,3,5-trimethylbenzene, triethyl phosphate, and a series of alkylphosphonates. PubMed: Functional effects of amino acid substitutions within the large binding pocket of the phosphotriesterase OpdA from Agrobacterium sp. P230. PubMed: Liquid chromatography electrospray tandem mass spectrometric and desorption electrospray ionization tandem mass spectrometric analysis of chemical warfare agents in office media typically collected during a forensic investigation. PubMed: The synthesis, structural, and spectroscopic characterization of uranium(IV) perrhenate complexes. PubMed: Indoor sorption of surrogates for sarin and related nerve agents. PubMed: [Identification of unknown peaks in foods during residual pesticide analysis]. PubMed: Evaluation of solid-phase microextraction with PDMS for air sampling of gaseous organophosphate flame-retardants and plasticizers. PubMed: Two-dimensional nonlinear wavelet compression of ion mobility spectra of chemical warfare agent simulants. PubMed: Detection, identification, and estimation of biological aerosols and vapors with a Fourier-transform infrared spectrometer. PubMed: Flame retardants in the indoor environment -- Part II: release of VOCs (triethylphosphate and halogenated degradation products) from polyurethane. PubMed: Phase purity of sol-gel-derived hydroxyapatite ceramic. PubMed: The effects of organic and inorganic phosphates on fertilization and early development in the sea urchin Lytechinus variegatus (Echinodermata: Echinoidea). PubMed: A convenient synthesis of a novel nucleoside analogue: 4-(alpha-diformyl-methyl)-1-(beta-D-ribofuranosyl)-2-pyrimidinone. PubMed: The binding of substrate analogs to phosphotriesterase. PubMed: [Synthesis and antiherpes activity of acyclovir phosphoesters]. PubMed: The synthesis of galactopyranosyl derivatives with beta-galactosidases of different origins. PubMed: The anatomic basis for arteriovenous shunting in human lower leg fascial flaps. PubMed: Solution structure of lariat RNA by 500 MHz NMR spectroscopy and molecular dynamics studies in water. PubMed: [Hygienic substantiation of maximum permissible level of triethylphosphate in reservoir water]. PubMed: Structural requirements for the inhibition of human monocyte carboxylesterase by organophosphorus compounds. PubMed: A new efficient synthetic method for 2- and 4-hydroxy-17 alpha-ethynylestradiol. PubMed: The quantitative determination of metabolites of 6-mercaptopurine in biological materials. VII. Chemical synthesis by phosphorylation of 6-thioguanosine 5'-monophosphate, 5'-diphosphate and 5'-triphosphate, and their purification and identification by reversed-phase/ion-pair high-performance liquid chromatography and by various enzymatic assays. PubMed: Synthesis and biological evaluation of some phosphate triester derivatives of the anti-cancer drug araC. PubMed: Physical basis of the effect of hemoglobin on the 31P NMR chemical shifts of various phosphoryl compounds. PubMed: The contribution of magnetic susceptibility effects to transmembrane chemical shift differences in the 31P NMR spectra of oxygenated erythrocyte suspensions. PubMed: Induction of the hepatic microsomal cytochrome P-450 system by trialkyl phosphorothioates in rats. PubMed: Toxicity of several phosphoric acid esters in rats. PubMed: Lipophilic 5'-(alkyl phosphate) esters of 1-beta-D-arabinofuranosylcytosine and its N4-acyl and 2,2'-anhydro-3'-O-acyl derivatives as potential prodrugs. PubMed: Double-column gas chromatography using packed pre-columns and glass capillary main columns. PubMed: Synthesis and biological activity of N6-(n-alkylureido)purine ribonucleosides and their 5'-phosphates. PubMed: Synthesis and antitumor activity of 5'-phosphates and cyclic 3',5'-phosphates derived from biologically active nucleosides. PubMed: Aliphatic analogues of nucleotides: synthesis and affinity towards nucleases. PubMed: Optical-rotatory-dispersion studies of compounds related to cholesterol in liposomes and the membranes of erythrocyte 'ghosts'. PubMed: Metabolic factors which influence triethyl phosphate-induced narcosis in rats. PubMed: Factors influencing dimethoate and triethyl phosphate-induced narcosis in rats and mice. PubMed: Anticholinesterase activity of triethyl phosphate resulting from an impurity. PubMed: Analogues of ribose 5-phosphate and 5-phosphoribosyl pyrophosphate. The preparation and properties of ribose 5-phosphorothioate and 5-phosphoribosyl 1-methylenediphosphonate. PubMed: The dipole moments of diethyl sulfite, triethyl phosphate and tetraethyl silicate. PubMed: The use of dimethoxytetraethyleneglycol and triethyl phosphate in histological technic.