tyloxapol
triton A-20
Identification
| Name | tyloxapol |
| IUPAC | formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol |
| CAS Number | 25301-02-4 |
| FDA UNII | Y27PUL9H56 |
| Molecular Formula | C17 H28 O3 |
| Molecular Weight | 280.40776000 |
| MDL Number | MFCD00149002 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 282.30 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.001980 mmHg @ 25.00 °C. (est) |
| Flash Point | > 230.00 °F. TCC ( > 110.00 °C. ) |
| logP (o/w) | 4.930 (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 > 5000 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LD50 > 5000 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for tyloxapol usage levels up to | not for fragrance use. |
| Recommendation for tyloxapol flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
alevaire
enuclene
exosurf
formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol
macrocyclon
superinone
superiuone
triton A-20
triton WR 1339
triton WR-1339
tyloxypal
PubMed:
Hippocampal lipoprotein lipase regulates energy balance in rodents.
PubMed:
In vitro antioxidant and antihyperlipidemic activities of Toddalia asiatica (L) Lam. leaves in Triton WR-1339 and high fat diet induced hyperlipidemic rats.
PubMed:
The effects of the decaffeination of coffee samples on platelet aggregation in hyperlipidemic rats.
PubMed:
Acute central neuropeptide Y administration increases food intake but does not affect hepatic very low-density lipoprotein (VLDL) production in mice.
PubMed:
Central nervous system neuropeptide Y signaling modulates VLDL triglyceride secretion.
PubMed:
Glycoprotein (90 kDa) isolated from Opuntia ficus-indica var. saboten MAKINO lowers plasma lipid level through scavenging of intracellular radicals in Triton WR-1339-induced mice.
PubMed:
Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4.
PubMed:
CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans.
PubMed:
Hypolipidaemic activity of seaweed from Karachi coast.
PubMed:
Surfactant-enhanced biodegradation of high molecular weight polycyclic aromatic hydrocarbons by stenotrophomonas maltophilia
PubMed:
Alimentary lipemia is enhanced in fiber-fed rats.
PubMed:
From the Food and Drug Administration.
PubMed:
Voluntary food consumption and gastric emptying in rats given intravenous Triton WR-1339.