xanthene
dibenzo[a,e]pyran
Identification
| Name | xanthene |
| IUPAC | 9H-xanthene |
| CAS Number | 92-83-1 |
| EINECS | 202-194-4 |
| FDA UNII | A762Z8101Y |
| Molecular Formula | C13 H10 O |
| Molecular Weight | 182.22190000 |
| MDL Number | MFCD00005055 |
| Nikkaji Number | J24.853C |
| Beilstein | 0133939 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 100.50 °C. @ 760.00 mm Hg |
| Boiling Point | 311.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.001000 mmHg @ 25.00 °C. (est) |
| Flash Point | 280.00 °F. TCC ( 137.50 °C. ) (est) |
| logP (o/w) | 4.230 |
| Soluble in | water, 1.018 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | subcutaneous-mouse LD50 690 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for xanthene usage levels up to | not for fragrance use. |
| Recommendation for xanthene flavor usage levels up to | not for flavor use. |
Potential Uses
Natural Occurrence
Synonyms
10H-9-oxa
anthracene
dibenzo[a,e]pyran
9H-
xanthene
PubMed:
Multi-dye residue analysis of triarylmethane, xanthene, phenothiazine and phenoxazine dyes in fish tissues by ultra-performance liquid chromatography-tandem mass spectrometry.
PubMed:
The promiscuous protein binding ability of erythrosine B studied by metachromasy (metachromasia).
PubMed:
Low-calorie bread baked with charred cellulose granules and wheat flour to eliminate toxic xanthene food dye in the alimentary canal.
PubMed:
New fluorescent pH sensors based on covalently linkable PET rhodamines.
PubMed:
Genotoxic and mutagenic effects of erythrosine B, a xanthene food dye, on HepG2 cells.
PubMed:
Adsorption mechanism for xanthene dyes to cellulose granules.
PubMed:
Xanthene food dye, as a modulator of Alzheimer's disease amyloid-beta peptide aggregation and the associated impaired neuronal cell function.
PubMed:
Hydrogen [corrected] peroxide-dependent photocytotoxicity by phloxine B, a xanthene-type food colorant.
PubMed:
Development of a fluorescence polarization immunoassay for the detection of melamine in milk and milk powder.
PubMed:
The food colorant erythrosine is a promiscuous protein-protein interaction inhibitor.
PubMed:
Toxicity of xanthene food dyes by inhibition of human drug-metabolizing enzymes in a noncompetitive manner.
PubMed:
Light emitting diode induced chemiluminescence and its application as a detector for high performance liquid chromatography.
PubMed:
Enhanced inactivation of foodborne pathogenic and spoilage bacteria by FD&C Red no. 3 and other xanthene derivatives during ultrahigh pressure processing.
PubMed:
Inhibition of human CYP3A4, UGT1A6, and P-glycoprotein with halogenated xanthene food dyes and prevention by superoxide dismutase.
PubMed:
Polybrominated hexahydroxanthene derivatives (PBHDs) and other halogenated natural products from the Mediterranean sponge Scalarispongia scalaris in marine biota.
PubMed:
The role of copper(II) in the bridging reactions of (+)-catechin by glyoxylic acid in a model white wine.
PubMed:
New polyphenolic compounds with xanthylium skeletons formed through reaction between (+)-catechin and glyoxylic acid.
PubMed:
Stimulating effect of xanthene dyes on immunoglobulin produced in vitro by rat spleen lymphocytes.
PubMed:
Effect of organic synthetic food colours on mitochondrial respiration.
PubMed:
Comparison of in vitro actions with behavioral effects of antimuscarinic agents.
PubMed:
Final report of the Color Additive Scientific Review Panel.
PubMed:
A review of the genotoxicity of food, drug and cosmetic colours and other azo, triphenylmethane and xanthene dyes.
PubMed:
Biochemical decomposition of coal-tar dyes. II. Acute toxicity of coal-tar dyes and their decomposed products.
PubMed:
Mutagenicity testing of certified food colors and related azo, xanthene and triphenylmethane dyes with the Salmonella/microsome system.
PubMed:
[Food additives and their mutagenic effect. VII. Testing of several xanthene dyes for their mutagenic effect on Escherichi coli].