chlorhexidine hydrochloride
imidodicarbonimidic diamide, N,N''''-1,6-hexanediylbis[N'-(4-chlorophenyl)-, hydrochloride (1:2)
Identification
| Name | chlorhexidine hydrochloride |
| CAS Number | 3697-42-5 |
| EINECS | 223-026-6 |
| FDA UNII | E64XL9U38K |
| Molecular Formula | C22 H32 Cl4 N10 |
| Molecular Weight | 578.37504000 |
| MDL Number | MFCD00068998 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| Soluble in | water, 564.5 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antimicrobial agents |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | subcutaneous-mouse LD50 > 5000 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for chlorhexidine hydrochloride usage levels up to | not for fragrance use. |
| Recommendation for chlorhexidine hydrochloride flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(1E)-2-[6-[[
amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;dihydrochloride
chlorhexidine dihydrochloirde
chlorhexidine HCl
chlorhexidinium dichloride
dantroche hibitane
1,1'-
hexamethylene bis(5-(p-chlorophenyl)biguanide), dihydrochloride
1,1'-
hexamethylenebis(5-(p-chlorophenyl)biguanide) dihydrochloride
1,1'-
hexamethylenebis[5-(p-chlorophenyl)-biguanide]-, dihydrochloride
N,N''''-
hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] dihydrochloride
N,N''''-1,6-
hexanediylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] dihydrochloride
imidodicarbonimidic diamide, N,N''''-1,6-hexanediylbis[N'-(4-chlorophenyl)-, hydrochloride (1:2)
2,4,11,13-
tetraazatetradecanediimidamide, N,N'-bis(4-chlorophenyl)-3,12-diimino-, dihydrochloride
2,4,11,13-
tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, dihydrochloride
2,4,11,13-
tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-,dihydrochloride
PubMed:
Resins-based denture soft lining materials modified by chlorhexidine salt incorporation: an in vitro analysis of antifungal activity, drug release and hardness.
PubMed:
Recurrent epistaxis in children.
PubMed:
Formulation and evaluation of periodontal in situ gel.
PubMed:
Antimicrobial activity of disinfectant agents incorporated into type IV dental stone.
PubMed:
The antimicrobial activity of a dentin conditioner combined with antibacterial agents.
PubMed:
Compressive strength of glass ionomer cements with dental antibacterial agents.
PubMed:
Inhibitory effects on selected oral bacteria of antibacterial agents incorporated in a glass ionomer cement.
PubMed:
Simultaneous determination of ingredients in an ointment by hydrophobic interaction electrokinetic chromatography.
PubMed:
Chromatography of crotamiton and its application to the determination of active ingredients in ointments.
PubMed:
An analysis of bacteremias during dental extractions. A double-blind, placebo-controlled study of chlorhexidine.
PubMed:
Contact hypersensitivity to topical antibacterial agents.
PubMed:
[Studies on the sensitivity of oral streptococci to chlorhexidine hydrochloride].
PubMed:
[Clinical and bacteriological assessment of the usefulness of lozenges containing chlorhexidine hydrochloride and anaesthesin for maintaining adequate oral hygiene in cases of wire splints on the teeth].
PubMed:
[Clinical and bacteriological evaluation of the usefulness of lozenges containing chlorhexidine hydrochloride and anesthesin in maintaining proper oral hygiene in cases of using wire dental splints].
PubMed:
The influence of various counter ions on the interaction of chlorhexidine with the hydrophilic contact lens polymer, poly(2-hydroxyethyl methacrylate).
PubMed:
Effect of chlorhexidine-coated dressings on plaque formation after gingivectomy.
PubMed:
[Effect of chlorhexidine hydrochloride on the formation of dental plaque in man (author's transl)].
PubMed:
Investigation on the effect on skin healing of a cream containing dexamethasone, chlorhexidine hydrochloride and nandrolone decanoate.
PubMed:
[The treatment of acute inflammations of the oral mucosa with chlorhexidine-hydrochloride (Hibitane)].