chlorhexidine hydrochloride

imidodicarbonimidic diamide, N,N''''-1,6-hexanediylbis[N'-(4-chlorophenyl)-, hydrochloride (1:2)

CAS: 3697-42-5 C22 H32 Cl4 N10 MW: 578.37504000

Identification

Namechlorhexidine hydrochloride
CAS Number3697-42-5
EINECS223-026-6
FDA UNIIE64XL9U38K
Molecular FormulaC22 H32 Cl4 N10
Molecular Weight578.37504000
MDL NumberMFCD00068998

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in water, 564.5 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantimicrobial agents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal Toxicitysubcutaneous-mouse LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for chlorhexidine hydrochloride usage levels up tonot for fragrance use.
Recommendation for chlorhexidine hydrochloride flavor usage levels up tonot for flavor use.

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Potential Uses

preservatives

Natural Occurrence

not found in nature

Synonyms

(1E)-2-[6-[[ amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;dihydrochloride chlorhexidine dihydrochloirde chlorhexidine HCl chlorhexidinium dichloride dantroche hibitane 1,1'- hexamethylene bis(5-(p-chlorophenyl)biguanide), dihydrochloride 1,1'- hexamethylenebis(5-(p-chlorophenyl)biguanide) dihydrochloride 1,1'- hexamethylenebis[5-(p-chlorophenyl)-biguanide]-, dihydrochloride N,N''''- hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] dihydrochloride N,N''''-1,6- hexanediylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] dihydrochloride imidodicarbonimidic diamide, N,N''''-1,6-hexanediylbis[N'-(4-chlorophenyl)-, hydrochloride (1:2) 2,4,11,13- tetraazatetradecanediimidamide, N,N'-bis(4-chlorophenyl)-3,12-diimino-, dihydrochloride 2,4,11,13- tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, dihydrochloride 2,4,11,13- tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-,dihydrochloride PubMed: Resins-based denture soft lining materials modified by chlorhexidine salt incorporation: an in vitro analysis of antifungal activity, drug release and hardness. PubMed: Recurrent epistaxis in children. PubMed: Formulation and evaluation of periodontal in situ gel. PubMed: Antimicrobial activity of disinfectant agents incorporated into type IV dental stone. PubMed: The antimicrobial activity of a dentin conditioner combined with antibacterial agents. PubMed: Compressive strength of glass ionomer cements with dental antibacterial agents. PubMed: Inhibitory effects on selected oral bacteria of antibacterial agents incorporated in a glass ionomer cement. PubMed: Simultaneous determination of ingredients in an ointment by hydrophobic interaction electrokinetic chromatography. PubMed: Chromatography of crotamiton and its application to the determination of active ingredients in ointments. PubMed: An analysis of bacteremias during dental extractions. A double-blind, placebo-controlled study of chlorhexidine. PubMed: Contact hypersensitivity to topical antibacterial agents. PubMed: [Studies on the sensitivity of oral streptococci to chlorhexidine hydrochloride]. PubMed: [Clinical and bacteriological assessment of the usefulness of lozenges containing chlorhexidine hydrochloride and anaesthesin for maintaining adequate oral hygiene in cases of wire splints on the teeth]. PubMed: [Clinical and bacteriological evaluation of the usefulness of lozenges containing chlorhexidine hydrochloride and anesthesin in maintaining proper oral hygiene in cases of using wire dental splints]. PubMed: The influence of various counter ions on the interaction of chlorhexidine with the hydrophilic contact lens polymer, poly(2-hydroxyethyl methacrylate). PubMed: Effect of chlorhexidine-coated dressings on plaque formation after gingivectomy. PubMed: [Effect of chlorhexidine hydrochloride on the formation of dental plaque in man (author's transl)]. PubMed: Investigation on the effect on skin healing of a cream containing dexamethasone, chlorhexidine hydrochloride and nandrolone decanoate. PubMed: [The treatment of acute inflammations of the oral mucosa with chlorhexidine-hydrochloride (Hibitane)].