chimyl alcohol

(S)-3-(hexadecyloxy)propane-1,2-diol

CAS: 506-03-6 C19 H40 O3 MW: 316.52540000

Identification

Namechimyl alcohol
IUPAC(2S)-3-hexadecoxypropane-1,2-diol
CAS Number506-03-6
EINECS208-026-6
FDA UNIIUJ10V6YY6H
Molecular FormulaC19 H40 O3
Molecular Weight316.52540000
Nikkaji NumberJ6.228F
Beilstein1724517

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 64.00 °C. @ 760.00 mm Hg
Boiling Point 445.18 °C. @ 760.00 mm Hg (est)
Flash Point 433.00 °F. TCC ( 223.00 °C. ) (est)
logP (o/w) 6.702 (est)
Soluble in water, 0.04798 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryemollients, viscosity controlling
Recommendation for chimyl alcohol usage levels up tonot for fragrance use.
Recommendation for chimyl alcohol flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

(S)- cetyl oxy-1,2-propane diol (2S)-3- hexadecoxypropane-1,2-diol (S)-3- hexadecyl oxy-1,2-propane diol (S)-3-( hexadecyl oxy) propane-1,2-diol 1-O- hexadecyl-sn-glycerol (S)-1- hexadecylglycerol L-a- hexadecylglycerol (S)-3-( hexadecyloxy)-1,2-propanediol (S)-3-( hexadecyloxy)propane-1,2-diol 1,2- propanediol, (S)-3-(hexadecyloxy)- (S)- testriol PubMed: Cytotoxic, cytostatic and HIV-1 PR inhibitory activities of the soft coral Litophyton arboreum. PubMed: Posttranslational regulation of fatty acyl-CoA reductase 1, Far1, controls ether glycerophospholipid synthesis. PubMed: Increasing plasmalogen levels protects human endothelial cells during hypoxia. PubMed: Inhibitory effect of 1-O (2 methoxy) hexadecyl glycerol and phenylbutyrate on the malignant properties of human prostate cancer cells. PubMed: 3'-End conjugates of minimally phosphorothioate-protected oligonucleotides with 1-O-hexadecylglycerol: synthesis and anti-ras activity in radiation-resistant cells. PubMed: Characterizations of Pneumocystis carinii and rat lung lipids: glyceryl ethers and fatty alcohols. PubMed: Lipase-catalyzed monoesterification of 1-O-hexadecylglycerol in organic solvents. PubMed: Purification and characterization of deep sea shark Centrophorus squamosus liver oil 1-O-alkylglycerol ether lipids. PubMed: 1-O-hexadecyl-2-metoxy-glycero-3-phosphatidylcholine--a methoxy ether lipid inhibiting platelet activating factor-induced platelet aggregation and neutrophil oxidative metabolism. PubMed: Evidence that the bradykinin-induced activation of phospholipase D and of the mitogen-activated protein kinase cascade involve different protein kinase C isoforms. PubMed: Chemical defense of common antarctic shallow-water nudibranchTritoniella belli eliot (Mollusca: Tritonidae) and its prey,Clavularia frankliniana rouel (Cnidaria: Octocorallia). PubMed: Alkyl glycerol monoethers in the marine sponge Desmapsamma anchorata. PubMed: Synthesis and secretion of plasmalogens by type-II pneumocytes. PubMed: Myocardial salvage by 1-O-hexadecyl-Sn-glycerol: possible role of peroxisomal dysfunction in ischemia reperfusion injury. PubMed: Myocardial salvage by chimyl alcohol: possible role of peroxisomal dysfunction in reperfusion injury. PubMed: Absorption of monoacylglycerols by small intestinal brush border membrane. PubMed: Dependence of an alkyl glycol-ether monooxygenase activity upon tetrahydropterins. PubMed: Biologically active ether lipids. Biotransformation of rac-1(3)-O-alkylglycerols in cell suspension cultures of rape and semisynthesis of 1-O-alkyl-2-palmitoyl-sn-glycero-3-phospho-(N-palmitoyl)ethanolamines, potent antitumor agents. PubMed: Interactions between alkylglycerols and human neutrophil granulocytes. PubMed: The glyceryl ethers of Paramecium phospholipids and phosphonolipids. PubMed: Affinity purification of alkylglycerol monooxygenase from rat liver microsomes by chimyl alcohol-Sepharose 4B column chromatography. PubMed: Thermoadaptive regulation of microsomal desaturase and electron-transport enzyme activities in lipid-manipulated Tetrahymena cells. Extent of unsaturated fatty acid production is dependent on membrane fluidity before temperature down-shift. PubMed: Metabolism of fatty acid, glycerol and a monoglyceride analogue by rat cardiac myocytes and perfused hearts. PubMed: The effect of temperature on glyceryl ethers in Tetrahymena pyriformis W. PubMed: Increasing the levels of ether-linked lipids in L-M cells by glyceryl ether supplementation depresses growth and choline utilization. PubMed: Metabolism of alpha-glyceryl ethers by Crithidia fasciculata. I. Study of the in vivo degradation of exogenous chimyl and batyl alcohols. PubMed: Metabolism of glycerol ether-containing lipids in dog fish (Squalus acanthias). PubMed: Metabolism of chimyl alcohol and phosphatidyl ethanolamine in the rat brain. PubMed: Metabolism of alpha-alkoxy glyceryl monoethers in rat liver, in vivo and in vitro. PubMed: The synthesis of(14)C- and (3)H-labeled glycerol ethers. PubMed: [Inhibiting effect of chimyl alcohol on lysolecithin-induced hemolysis]. PubMed: Digestion, absorption and metabolism of chimyl alcohol fed as free alcohol or as alkoxydiglyceride. PubMed: Absorption of chimyl alcohol in man. PubMed: The intestinal absorption and metabolism of chimyl alcohol in the rat.