4-tert-butyl phenol
para-tert-butylphenol
Identification
| Name | 4-tert-butyl phenol |
| IUPAC | 4-tert-butylphenol |
| CAS Number | 98-54-4 |
| EINECS | 202-679-0 |
| FDA UNII | O81VMW36CV |
| Molecular Formula | C10 H14 O |
| Molecular Weight | 150.22078000 |
| MDL Number | MFCD00002367 |
| Nikkaji Number | J3.579C |
| Beilstein | 1817334 |
| XlogP3 | 3.30 (est) |
Regulatory
| JECFA Food Flavoring | 733 4-(1,1-dimethylethyl) phenol |
| DG SANTE Food Flavourings | 04.064 4-(1,1-dimethylethyl)phenol |
| DG SANTE Food Contact Materials | 4-(1,1-dimethylethyl)phenol |
| FEMA Number | 3918 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 98-54-4 ; 4-(1,1-DIMETHYLETHYL)PHENOL |
| FDA Regulation | FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS |
Physical Properties
| Appearance | colorless to amber powder (est) |
| Assay | 99.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 98.00 °C. @ 760.00 mm Hg |
| Boiling Point | 237.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.038100 mmHg @ 25.00 °C. |
| Flash Point | > 200.00 °F. TCC ( > 93.33 °C. ) |
| logP (o/w) | 3.310 |
| Soluble in | alcohol |
| Insoluble in | water |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | not used anymore |
Organoleptic Properties
| Odor Description | at 1.00 % in propylene glycol. |
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | oral-rat LD50 3250 ul/kg |
| Dermal Toxicity | skin-rabbit LD50 2520 ul/kg |
| Inhalation Toxicity | inhalation-rat LCLo 5600 mg/m3/4H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | food contact resinous and polymeric coatings |
| IFRA Critical Effect | Dermal sensitization, dermal depigmentation |
| Recommendation for 4-tert-butyl phenol usage levels up to | PROHIBITED: Should not be used as a fragrance ingredient. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 0.012 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA) | 0.01 (μg/capita/day) |
| baked goods | 0.10000 |
| beverages(nonalcoholic) | 0.50000 |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | - |
| fruit ices | - |
| gelatins / puddings | 0.01000 |
| granulated sugar | - |
| gravies | - |
| hard candy | 0.10000 |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | 1.00000 |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
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Potential Uses
Natural Occurrence
Synonyms
butyl phen
p-tert-
butyl phenol
para-tert-
butyl phenol
1-tert-
butyl-4-hydroxybenzene
4-(tert-
butyl)phenol
4-tert-
butylphenol
p-tert-
butylphenol
para-tert-
butylphenol
4-(1,1-
dimethyl ethyl) phenol
4-(1,1-
dimethyl)ethylphenol
4-(1,1-
dimethylethyl) phenol
4-(1,1-
dimethylethyl)phenol
1-
hydroxy-4-tert-butyl benzene
1-
hydroxy-4-tert-butylbenzene
4-(2-
methyl-2-propanyl)phenol
paraterciobutylphenol resin SC / 108575
phenol, 4-(1,1-dimethylethyl)-
phenol, 4-t-butyl-
terbutol
PubMed:
The alkylphenols 4-nonylphenol, 4-tert-octylphenol and 4-tert-butylphenol aggravate atopic dermatitis-like skin lesions in NC/Nga mice.
PubMed:
Indirect inactivation of tyrosinase in its action on 4-tert-butylphenol.
PubMed:
Absence of experimental evidence of a delta-shock in the system phenetole and 4-tert-butylphenol on Zorbax 300SB-C18.
PubMed:
Occurrence of 4-tert-butylphenol (4-t-BP) biodegradation in an aquatic sample caused by the presence of Spirodela polyrrhiza and isolation of a 4-t-BP-utilizing bacterium.
PubMed:
Toward a better understanding of Fe(III)-EDDS photochemistry: theoretical stability calculation and experimental investigation of 4-tert-butylphenol degradation.
PubMed:
A Biomimetic Mechanism for the Copper-Catalyzed Aerobic Oxygenation of 4-tert-Butylphenol.
PubMed:
New enzymatically polymerized copolymers from 4-tert-butylphenol and 4-ferrocenylphenol and their modification and inclusion complexes with β-cyclodextrin.
PubMed:
The 4-tert-butylphenol-utilizing bacterium Sphingobium fuliginis OMI can degrade bisphenols via phenolic ring hydroxylation and meta-cleavage pathway.
PubMed:
Isolation and characterization of 4-tert-butylphenol-utilizing Sphingobium fuliginis strains from Phragmites australis rhizosphere sediment.
PubMed:
Aromatic ring cleavage of 2-amino-4-tert-butylphenol by a nonheme iron(II) complex: functional model of 2-aminophenol dioxygenases.
PubMed:
Solid phase analytical derivatization of anthropogenic and natural phenolic estrogen mimics with pentafluoropyridine for gas chromatography-mass spectrometry.
PubMed:
Development of a fabric phase sorptive extraction with high-performance liquid chromatography and ultraviolet detection method for the analysis of alkyl phenols in environmental samples.
PubMed:
Fe(III)-EDDS complex in Fenton and photo-Fenton processes: from the radical formation to the degradation of a target compound.
PubMed:
Structure and vibrational spectrum of the hydrogen-bonded system between 4-tert-butylphenol and N-bases: Ab initio and DFT studies.
PubMed:
Prooxidant actions of bisphenol A (BPA) phenoxyl radicals: implications to BPA-related oxidative stress and toxicity.
PubMed:
3d early transition metal complexes supported by a new sterically demanding aryloxide ligand.
PubMed:
Effects of 4-tert-octylphenol, 4-tert-butylphenol, and diethylstilbestrol on prenatal testosterone surge in the rat.
PubMed:
[Kinetics of endocrine disrupting chemical 4-tert-butylphenol during chlorination in aqua].
PubMed:
In vitro effects of diethylstilbestrol, genistein, 4-tert-butylphenol, and 4-tert-octylphenol on steroidogenic activity of isolated immature rat ovarian follicles.
PubMed:
Copper-promoted overall transformation of 4-tert-butylphenol to its para-hydroxyquinonic derivative, 2-hydroxy-5-tert-butyl-1,4-benzoquinone. Biomimetic studies on the generation of topaquinone in copper amine oxidases.
PubMed:
Tyrosinase-mediated formation of a reactive quinone from the depigmenting agents, 4-tert-butylphenol and 4-tert-butylcatechol.
PubMed:
Kinetics study of the oxidation of 4-tert-butylphenol by tyrosinase.
PubMed:
Magnetically confined hydrophobic nanoparticles for the microextraction of endocrine-disrupting phenols from environmental waters.
PubMed:
A role for tyrosinase-related protein 1 in 4-tert-butylphenol-induced toxicity in melanocytes: Implications for vitiligo.
PubMed:
Contact allergy to 2-hydroxy-5-tert-butyl benzylalcohol and 2,6-bis(hydroxymethyl)-4-tert-butylphenol, components of a phenolic resin used in marking pens.
PubMed:
Determination of 4-tert.-butylphenol and 4-tert.-butylcatechol in cosmetic products by reversed-phase high-performance liquid chromatography.
PubMed:
A convenient screening method to differentiate phenolic skin whitening tyrosinase inhibitors from leukoderma-inducing phenols.
PubMed:
Patch test results in children and adolescents across Europe Analysis of the ESSCA Networkª 2002-2010.
PubMed:
Cu(II)-mediated phenol oxygenation: chemical evidence implicates a unique role of the enzyme active site in promoting the chemically difficult tyrosine monooxygenation in TPQ cofactor biogenesis of copper amine oxidases.
PubMed:
Certification of reference materials for the determination of alkylphenols.
PubMed:
Discrimination between alternative substrates and inhibitors of tyrosinase.
PubMed:
Chemical category approach of genotoxicity studies for branched alkylphenols.
PubMed:
Shaping of mesoporous AISBA-15 as cylindrical nano reactor for tertiary butylation of phenol.
PubMed:
Anionic bipyridyl ligands for applications in metallasupramolecular chemistry.
PubMed:
Is drinking water a major route of human exposure to alkylphenol and bisphenol contaminants in France?
PubMed:
Tyrosinase action on monophenols: evidence for direct enzymatic release of o-diphenol.
PubMed:
Allergic contact dermatitis from chromate and 4-tert-butylphenol-formaldehyde resin in a father and daughter.
PubMed:
An on-line push/pull perfusion-based hollow-fiber liquid-phase microextraction system for high-performance liquid chromatographic determination of alkylphenols in water samples.
PubMed:
Sustainable biodegradation of phenolic endocrine-disrupting chemicals by Phragmites australis-rhizosphere bacteria association.
PubMed:
Experimental evidence of a delta-shock in nonlinear chromatography.
PubMed:
Band splitting in overloaded isocratic elution chromatography I. The experimental evidence.
PubMed:
Apoptosis regulators and responses in human melanocytic and keratinocytic cells.
PubMed:
Determination of endocrine-disrupting phenols in water samples by a new manual shaking-enhanced, ultrasound-assisted emulsification microextraction method.
PubMed:
Dummy molecularly imprinted polymers as the coating of stir bar for sorptive extraction of bisphenol A in tap water.
PubMed:
Determination of phenols with ion chromatography-online electrochemical derivatization based on porous electrode-fluorescence detection.
PubMed:
Synthesis, structure and ethylene polymerisation behaviour of vanadium(IV and V) complexes bearing chelating aryloxides.
PubMed:
Biodegradation of bisphenol A and 4-alkylphenols by Novosphingobium sp. strain TYA-1 and its potential for treatment of polluted water.
PubMed:
Comparative study of IQ-ultra and Finn Chambers test methodologies in detecting 10 common standard allergens that cause allergic contact dermatitis.
PubMed:
Effect of 3-hydroxyanthranilic acid on mushroom tyrosinase activity.
PubMed:
Band splitting in overloaded isocratic elution chromatography III. Modeling of adsorbate-adsorbate interactions by a two-component extension of a BET kinetic isotherm model.
PubMed:
Band splitting in overloaded isocratic elution chromatography II. New competitive adsorption isotherms.
PubMed:
Low-dose exposure to alkylphenols adversely affects the sexual development of Atlantic cod (Gadus morhua): acceleration of the onset of puberty and delayed seasonal gonad development in mature female cod.
PubMed:
Preparation of metal wire supported solid-phase microextraction fiber coated with multi-walled carbon nanotubes.
PubMed:
Preferential secretion of inducible HSP70 by vitiligo melanocytes under stress.
PubMed:
Removal of alkylphenols from polluted sites using surfactant-assisted soil washing and photocatalysis.
PubMed:
Enhanced removal of aqueous BPA model compounds using Metalloligs.
PubMed:
Synthesis and reactivity of fluorous and nonfluorous aryl and alkyl iodine(III) dichlorides: new chlorinating reagents that are easily recycled using biphasic protocols.
PubMed:
Kinetic cooperativity of tyrosinase. A general mechanism.
PubMed:
Determination of antioxidants in new and used lubricant oils by headspace-programmed temperature vaporization-gas chromatography-mass spectrometry.
PubMed:
Determination of endocrine-disrupting compounds in cereals by pressurized liquid extraction and liquid chromatography-mass spectrometry. Study of background contamination.
PubMed:
Effluents from oil production activities contain chemicals that interfere with normal function of intra- and extra-cellular estrogen binding proteins.
PubMed:
Indoor air pollution by alkylphenols in Tokyo.
PubMed:
Mechanistic implications of variable stoichiometries of oxygen consumption during tyrosinase catalyzed oxidation of monophenols and o-diphenols.
PubMed:
Brominated phenols: characterization of estrogen-like activity in the human breast cancer cell-line MCF-7.
PubMed:
A model molecule of the hydrogen-bonded chain in the active site of bacteriorhodopsin.
PubMed:
[Degradation of endocrine disrupting chemicals(EDCs)-BP by combination of UV/ micro-aeration process and impact factors].
PubMed:
Effects of alkylphenols on glycerophospholipids and cholesterol in liver and brain from female Atlantic cod (Gadus morhua).
PubMed:
Provoking factors, including chemicals, in Dutch patients with vitiligo.
PubMed:
A confirmatory method for the determination of phenolic endocrine disruptors in honey using restricted-access material-liquid chromatography-tandem mass spectrometry.
PubMed:
Synthesis, characterization, and stability of iron (III) complex ions possessing phenanthroline-based ligands.
PubMed:
Thermochemical and Theoretical Study of tert-Butyl and Di-tert-butylphenol Isomers.
PubMed:
Reactivity of a 10-I-3 hypervalent iodine trifluoromethylation reagent with phenols.
PubMed:
Synthesis and structures of niobium(V) complexes stabilized by linear-linked aryloxide trimers.
PubMed:
Determination of endocrine disruptors in honey by CZE-MS using restricted access materials for matrix cleanup.
PubMed:
Vitiligo-inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8.
PubMed:
Multiple headspace-solid-phase microextraction as a powerful tool for the quantitative determination of volatile radiolysis products in a multilayer food packaging material sterilized with γ-radiation.
PubMed:
Removal of BPA model compounds and related substances by means of column chromatography using Octolig®.
PubMed:
Determination of endocrine disrupting compounds using temperature-dependent inclusion chromatography: I. Optimization of separation protocol.
PubMed:
[Induction of occupational leucoderma and vitiligo. Can butylated hydroxytoluene induce vitiligo similarly to p-tert-butylphenol?].
PubMed:
Effect-directed investigation and interactive effect of organic toxicants in landfill leachates combining Microtox test with RP-HPLC fractionation and GC/MS analysis.
PubMed:
Uptake and tissue distribution of C4-C7 alkylphenols in Atlantic cod (Gadus morhua): relevance for biomonitoring of produced water discharges from oil production.
PubMed:
Column silylation method for determining endocrine disruptors from environmental water samples by solid phase micro-extraction.
PubMed:
Effects of alkylphenols on the reproductive system of Atlantic cod (Gadus morhua).
PubMed:
European Standard Series patch test results from a contact dermatitis clinic in Israel during the 7-year period from 1998 to 2004.
PubMed:
Stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography--mass spectrometry for measurement of phenolic xenoestrogens in human urine samples.
PubMed:
2:2 Fe(III):ligand and "adamantane core" 4:2 Fe(III):ligand (hydr)oxo complexes of an acyclic ditopic ligand.
PubMed:
Inhibition of peroxidase-catalyzed oxidation of 3,3 ,5,5 -tetramethylbenzidine by aminophenols.
PubMed:
[Estimation of daily intake of phenols in hospital meal samples].
PubMed:
Determination of weakly acidic endocrine-disrupting compounds by liquid chromatography-mass spectrometry with post-column base addition.
PubMed:
Photodegradation of bisphenol-A with TiO2 immobilized on the glass tubes including the UV light lamps.
PubMed:
Effects of alkylphenols on CYP1A and CYP3A expression in first spawning Atlantic cod (Gadus morhua).
PubMed:
Shoe contact dermatitis in Israel.
PubMed:
Separation and on-line concentration of bisphenol A and alkylphenols by micellar electrokinetic chromatography with cationic surfactant.
PubMed:
[Analysis of phenolic compounds in mineral water by high performance liquid chromatography (HPLC)].
PubMed:
Developmental aspects of human hepatic drug glucuronidation in young children and adults.
PubMed:
Floral Origin Markers of Chestnut and Lime Tree Honeys.
PubMed:
Determination of 4-nonylphenol, nonylphenol monoethoxylate, nonylphenol diethoxylate and other alkylphenols in fish and shellfish by high-performance liquid chromatography with fluorescence detection.
PubMed:
Oxidation by mushroom tyrosinase of monophenols generating slightly unstable o-quinones.
PubMed:
Issues arising when interpreting results from an in vitro assay for estrogenic activity.
PubMed:
Competitive binding of xenobiotic oestrogens to rat alpha-fetoprotein and to sex steroid binding proteins in human and rainbow trout (Oncorhynchus mykiss) plasma.
PubMed:
Occupational exposure to estrogenic chemicals and the occurrence of breast cancer: an exploratory analysis.
PubMed:
Expression and functional domains of rabbit liver UDP-glucuronosyltransferase 2B16 and 2B13.
PubMed:
Chromatographic analysis of water and wine samples for phenolic compounds released from food-contact epoxy resins.
PubMed:
The relationship between Van der Waals volume of 4-substituent of phenol and sulfation in the rat.
PubMed:
Three-dimensional mesoporous gallosilicate with Pm3n symmetry and its unusual catalytic performances.
PubMed:
Characterization of alkylphenol metabolites in fish bile by enzymatic treatment and HPLC-fluorescence analysis.
PubMed:
Uptake of some selected aquatic pollutants in semipermeable membrane devices (SPMDs) and the polar organic chemical integrative sampler (POCIS).
PubMed:
Chemistry of 4-alkylaryloxenium ion "precursors": sound and fury signifying something?
PubMed:
Reactivity study of a hydroperoxodicopper(II) complex: hydroxylation, dehydrogenation, and ligand cross-link reactions.
PubMed:
Activation of dual apoptotic pathways in human melanocytes and protection by survivin.
PubMed:
Water purification through bioconversion of phenol compounds by tyrosinase and chemical adsorption by chitosan beads.
PubMed:
Simultaneous determination of alkylphenols and bisphenol A in river water by stir bar sorptive extraction with in situ acetylation and thermal desorption-gas chromatography-mass spectrometry.
PubMed:
Effects of alkylphenols on redox status in first spawning Atlantic cod (Gadus morhua).
PubMed:
Simultaneous measurement of urinary bisphenol A and alkylphenols by automated solid-phase extractive derivatization gas chromatography/mass spectrometry.
PubMed:
Phthalates, alkylphenols, pesticides, polybrominated diphenyl ethers, and other endocrine-disrupting compounds in indoor air and dust.
PubMed:
Separation and on-line concentration of bisphenol A and alkylphenols by micellar electrokinetic chromatography with anionic surfactant.
PubMed:
Comparison of the adsorption equilibrium of a few low-molecular mass compounds on a monolithic and a packed column in reversed-phase liquid chromatography.
PubMed:
Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications.
PubMed:
Monobenzyl ether of hydroquinone and 4-tertiary butyl phenol activate markedly different physiological responses in melanocytes: relevance to skin depigmentation.
PubMed:
Determination of dimethyl fumarate and other potential allergens in desiccant and antimould sachets.
PubMed:
Effects of environmental relevant doses of pollutants from offshore oil production on Atlantic cod (Gadus morhua).
PubMed:
Patch testing with the irritant sodium lauryl sulfate (SLS) is useful in interpreting weak reactions to contact allergens as allergic or irritant.
PubMed:
Patch-test reactions to plastic and glue allergens.
PubMed:
Increase in the levels of chaperone proteins by exposure to beta-estradiol, bisphenol A and 4-methoxyphenol in human cells transfected with estrogen receptor alpha cDNA.
PubMed:
[Influence of p-tert-butylphenol on immunity of mice].
PubMed:
Pharmacological properties of BN82451: a novel multitargeting neuroprotective agent.
PubMed:
An expedient one-pot synthesis of para-tert-butylcalix[8]- and [9]arene.
PubMed:
Binding of alkylphenols and alkylated non-phenolics to the rainbow trout (Oncorhynchus mykiss) plasma sex steroid-binding protein.
PubMed:
Allergic contact dermatitis due to orthopedic shoes and a prosthesis for an amputated foot.
PubMed:
Effect of the endcapping of reversed-phase high-performance liquid chromatography adsorbents on the adsorption isotherm.
PubMed:
[Improved method for determining bisphenol A in polycarbonate products without using dichloromethane].
PubMed:
Effects of bisphenol A and its derivatives on the response of GABA(A) receptors expressed in Xenopus oocytes.
PubMed:
Effects of commonly used mitogens on the cytotoxicity of 4-tertiary butylphenol to human melanocytes.
PubMed:
Contact allergy to the monomers of p-tert-butylphenol-formaldehyde resin in the guinea pig.
PubMed:
Active sensitization and occupational allergic contact dermatitis caused by para-tertiary-butylcatechol.
PubMed:
Hydrogen peroxide-dependent 4-t-butylphenol hydroxylation by tyrosinase--a new catalytic activity.
PubMed:
Is Bindi-induced depigmentation common in patients predisposed to vitiligo?
PubMed:
[Assessment of occupational exposure to p-tert-butylphenol in synthetic resin factories].
PubMed:
Contact depigmentation by adhesive material of bindi.
PubMed:
Contact depigmentation of the breast.
PubMed:
Contact depigmentation from free para-tertiary-butylphenol in bindi adhesive.
PubMed:
Urinary metabolite levels in workers handling p-tert-butylphenol as an index of personal exposure.
PubMed:
Modification of N-methyl-N'-nitro-N-nitrosoguanidine-induced forestomach and glandular stomach carcinogenesis by phenolic antioxidants in rats.
PubMed:
Occupational vitiligo due to unsuspected presence of phenolic antioxidant byproducts in commercial bulk rubber.
PubMed:
[Occupational asthma due to para-tert-butylphenol: case report].
PubMed:
Occupational leukoderma and contact dermatitis from paratertiary-butylphenol.
PubMed:
A study on the synthesis of calix[4 and 6]arenes using alternately arranged phloroglucinols and p-tert-butylphenols.
PubMed:
Shoe dermatitis from para-tertiary butylphenol formaldehyde.
PubMed:
Molecular and electronic structure of square-planar gold complexes containing two 1,2-Di(4-tert-butylphenyl)ethylene-1,2-dithiolato ligands: [Au(2L)2]1+/0/1-/2-. A combined experimental and computational study.
PubMed:
4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo.
PubMed:
An attempt to improve diagnostics of contact allergy due to epoxy resin systems. First results of the multicentre study EPOX 2002.
PubMed:
Effect of deoxyarbutin on melanogenesis: in vivo comparison with other melanogenesis inhibitor.
PubMed:
Alkylphenol and bisphenol A levels in rubber products.
PubMed:
Molecular recognition by beta-cyclodextrin derivatives: FEP vs MM/PBSA study.
PubMed:
The cytotoxicity and apoptosis induced by 4-tertiary butylphenol in human melanocytes are independent of tyrosinase activity.
PubMed:
Effects of 4-tertiary butylphenol on the tyrosinase activity in human melanocytes.
PubMed:
Demonstration of the contact sensitizer p-tert-butylcatechol in p-tert-butylphenol formaldehyde resin.
PubMed:
The acute toxicity of selected alkylphenols to young and adult Daphnia magna.
PubMed:
Is micropigmentation surgery an answer to stable bindi-induced depigmentation?
PubMed:
Identification of causative chemicals of allergic contact dermatitis using a combination of patch testing in patients and chemical analysis. Application to cases from rubber footwear.
PubMed:
Allergic contact dermatitis from para-tertiary-butylphenol-formaldehyde resin (PTBP-F-R) in Northern Ireland.
PubMed:
Allergic contact dermatitis of the lip margins from para-tertiary-butylphenol in a lip liner.
PubMed:
Effects of p-tert-butylphenyl trans-4-guanidinomethylcyclohexane carboxylate hydrochloride (NCO-650) and its metabolite, p-tert-butylphenol(BP) on drug-metabolizing enzymes and fine structure in rat liver.
PubMed:
Acute toxicity and primary irritation of para-tertiary butylphenol.
PubMed:
[Skin and systemic disease caused by occupational contact with p-tert-butylphenol. Case reports].
PubMed:
[Analysis of para-tert-butylphenol, phenol and diphenylpropane].
PubMed:
[Shoe eczema caused by para-tertiary butylphenol. Making shoes with glue free of para-tertiary butylphenol].
PubMed:
[Dyschromia caused by para-tert-butylphenol].
PubMed:
Occupational vitiligo: clinical and epidemiological aspects.
PubMed:
[Vitiligo due to p-tert-butylphenol].
PubMed:
[Chemical vitiligo caused by para-tertiary butyl phenol (author's transl)].
PubMed:
[Vitiligo from p-tert. butylphenol; a contribution to the problem of the internal manifestations of this occupational disease].
PubMed:
Determination of phenolic xenoestrogens in water by liquid chromatography with coulometric-array detection.