lauryl stearate

octadecanoic acid, dodecyl ester

CAS: 5303-25-3 C30 H60 O2 MW: 452.80660000

Identification

Namelauryl stearate
CAS Number5303-25-3
EINECS226-150-9
FDA UNII8M9A08VM57
Molecular FormulaC30 H60 O2
Molecular Weight452.80660000
MDL NumberMFCD00059290
Nikkaji NumberJ111.066G

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 484.94 °C. @ 760.00 mm Hg (est)
Flash Point 492.00 °F. TCC ( 255.50 °C. ) (est)
logP (o/w) 14.032 (est)
Soluble in water, 3.259e-009 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryemollients, skin conditioning
Recommendation for lauryl stearate usage levels up tonot for fragrance use.
Recommendation for lauryl stearate flavor usage levels up tonot for flavor use.

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Potential Uses

emollients

Natural Occurrence

not found in nature

Synonyms

dodecyl octadecanoate dodecyl stearate octadecanoic acid dodecyl ester octadecanoic acid, dodecyl ester stearic acid dodecyl ester stearic acid, dodecyl ester PubMed: Effect of olive storage conditions on Chemlali olive oil quality and the effective role of fatty acids alkyl esters in checking olive oils authenticity. PubMed: Excipient-Process Interactions and their Impact on Tablet Compaction and Film Coating. PubMed: Lipase immobilized catalytically active membrane for synthesis of lauryl stearate in a pervaporation membrane reactor. PubMed: Rapid classification of pharmaceutical ingredients with Raman spectroscopy using compressive detection strategy with PLS-DA multivariate filters. PubMed: Understanding and optimizing the dual excipient functionality of sodium lauryl sulfate in tablet formulation of poorly water soluble drug: wetting and lubrication. PubMed: Formulation and evaluation of olanzapine matrix pellets for controlled release. PubMed: Improving the hardness of dry granulated tablets containing sodium lauryl sulfate. PubMed: An experimental investigation of the effect of the amount of lubricant on tablet properties. PubMed: Final report on the safety assessment of sodium cetearyl sulfate and related alkyl sulfates as used in cosmetics. PubMed: Buccal drug delivery of pravastatin sodium. PubMed: Comedogenicity in rabbit: some cosmetic ingredients/vehicles. PubMed: Evidence for vesicle formation from 1:1 nonionic surfactant span 60 and fatty alcohol mixtures in aqueous ethanol: potential delivery vehicle composition. PubMed: Importance of using physiologically relevant volume of dissolution medium to correlate the oral exposure of formulations of BMS-480188 mesylate. PubMed: The tandem repeated irritation test: a new method to assess prevention of irritant combination damage to the skin. PubMed: Unexpected skin barrier influence from nonionic emulsifiers. PubMed: The impact of formulation and process changes on in vitro dissolution and the bioequivalence of piroxicam capsules. PubMed: Design and in vivo evaluation of ultrafine inorganic-oxide-containing-sunscreen formulations. PubMed: The effect of modification of acrylic resins on controlled release and bioadhesion. PubMed: Effect of cogrinding with various kinds of surfactants on the dissolution behavior of phenytoin. PubMed: Efficacy of skin barrier creams (IV). The repetitive irritation test (RIT) with a set of 4 standard irritants. PubMed: Efficacy of skin barrier creams (I). The repetitive irritation test (RIT) in the guinea pig. PubMed: Bioadhesive dosage form for peroral administration of timolol base. PubMed: Studies on flufenamic acid capsules and tablets. PubMed: Effect of shear mixing on in vitro drug release of capsule formulations containing lubricants. PubMed: The influence of additives on the presentation of a drug in hard gelatin capsules. PubMed: The in vitro bioavailability of various drugs formulated as hard gelatin capsules. PubMed: Effect of nonionic surfactants on percutaneous absorption of salicylic acid and sodium salicylate in the presence of dimethyl sulfoxide. PubMed: Factors effecting drug release from inert matrices. Part 1: effects of surfactants on the release of quinine sulfate. PubMed: EFFECTS OF PROTEIN, LIPIDS, AND SURFACTANTS ON THE ANTIMICROBIAL ACTIVITY OF SYNTHETIC STEROIDS.