magnesium aluminum silicate
aluminum magnesium silicon oxide
Identification
| Name | magnesium aluminum silicate |
| CAS Number | 1327-43-1 |
| EINECS | 215-478-8 |
| FDA UNII | 6M3P64V0NC |
| Molecular Formula | Al Mg O4 Si + |
| Molecular Weight | 143.36863860 |
Regulatory
Physical Properties
| Appearance | white powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| logP (o/w) | 0.650 (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | absorbents |
Organoleptic Properties
| Odor Strength | none |
| Odor Description | at 100.00 %. |
Safety Information
| Oral/Parenteral Toxicity | oral-rat LD50 > 16000 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for magnesium aluminum silicate usage levels up to | not for fragrance use. |
| Recommendation for magnesium aluminum silicate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
aluminosilicic acid magnesium salt
aluminum magnesium silicate
aluminum magnesium silicon oxide
magnesium aluminosilicate
magnesium aluminum silicate NF type 1A (225 - 600 CPS)
magnesium aluminum silicate NF type 1B (150 - 450 CPS)
magnesium aluminum silicate NF type 1C (800 - 2200 CPS)
magnesium aluminum silicate NF type 2A (100 - 300 CPS)
magnesium silicate aluminate
neusilin UFL2
PubMed:
Amorphization of itraconazole by inorganic pharmaceutical excipients: comparison of excipients and processing methods.
PubMed:
Quaternary polymethacrylate-magnesium aluminum silicate films: molecular interactions, mechanical properties and tackiness.
PubMed:
The effect of polymer content on the non-newtonian behavior of acetaminophen suspension.
PubMed:
Nicotine-magnesium aluminum silicate microparticle surface modified with chitosan for mucosal delivery.
PubMed:
Characterization of chitosan-magnesium aluminum silicate nanocomposite films for buccal delivery of nicotine.
PubMed:
The addition of modified attapulgite reduces the emission of nitrous oxide and ammonia from aerobically composted chicken manure.
PubMed:
Novel composite blend microbeads of sodium alginate coated with chitosan for controlled release of amoxicillin.
PubMed:
Influence of pH modifiers and HPMC viscosity grades on nicotine-magnesium aluminum silicate complex-loaded buccal matrix tablets.
PubMed:
Synthesis of an attapulgite clay@carbon nanocomposite adsorbent by a hydrothermal carbonization process and their application in the removal of toxic metal ions from water.
PubMed:
Preparation and characterization of nicotine-magnesium aluminum silicate complex-loaded sodium alginate matrix tablets for buccal delivery.
PubMed:
Novel chitosan-magnesium aluminum silicate nanocomposite film coatings for modified-release tablets.
PubMed:
The roughness, microhardness, and surface analysis of nanocomposites after application of topical fluoride gels.
PubMed:
Chitosan-magnesium aluminum silicate nanocomposite films: physicochemical characterization and drug permeability.
PubMed:
Propranolol-magnesium aluminum silicate complex dispersions and particles: characterization and factors influencing drug release.
PubMed:
Alginate-magnesium aluminum silicate films for buccal delivery of nicotine.
PubMed:
Physicochemical properties of magnesium aluminum silicate (smectone) gels prepared using electrolytic-reduction ion water (2): Effects of various salts on the phase diagram.
PubMed:
Polymer-magnesium aluminum silicate composite dispersions for improved physical stability of acetaminophen suspensions.
PubMed:
Dissolution and powder flow characterization of solid self-emulsified drug delivery system (SEDDS).
PubMed:
Alginate-magnesium aluminum silicate films: importance of alginate block structures.
PubMed:
Interaction of nicotine with magnesium aluminum silicate at different pHs: characterization of flocculate size, zeta potential and nicotine adsorption behavior.
PubMed:
Chitosan-magnesium aluminum silicate composite dispersions: characterization of rheology, flocculate size and zeta potential.
PubMed:
Sodium alginate-magnesium aluminum silicate composite gels: characterization of flow behavior, microviscosity, and drug diffusivity.
PubMed:
Alginate-magnesium aluminum silicate composite films: effect of film thickness on physical characteristics and permeability.
PubMed:
Alginate-magnesium aluminum silicate films: effect of plasticizers on film properties, drug permeation and drug release from coated tablets.
PubMed:
Multi functional uptake behaviour of materials prepared by calcining waste paper sludge.
PubMed:
Investigation of novel alginate-magnesium aluminum silicate microcomposite films for modified-release tablets.
PubMed:
Molecular interaction in alginate beads reinforced with sodium starch glycolate or magnesium aluminum silicate, and their physical characteristics.
PubMed:
Characteristics of bricks made from waste steel slag.
PubMed:
Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate, sodium magnesium silicate, zirconium silicate, attapulgite, bentonite, Fuller's earth, hectorite, kaolin, lithium magnesium silicate, lithium magnesium sodium silicate, montmorillonite, pyrophyllite, and zeolite.
PubMed:
[Personal experience with administration of Smektit (hydrated magnesium aluminum silicate) in the treatment of diarrhea of non-infectious origin and diarrhea after resection of the large intestine].
PubMed:
Reduced tetracycline bioavailability caused by magnesium aluminum silicate in liquid formulations of bismuth subsalicylate.
PubMed:
Stability of Allopurinol Suspension Compounded from Tablets.
PubMed:
Interaction between polyethylene films and bromhexine HCl in solid dosage form. IV. Prevention of the sorption by addition of magnesium aluminum silicate.
PubMed:
Stability of acetazolamide in suspension compounded from tablets.
PubMed:
Physical and chemical changes of medicinals in mixtures with adsorbents in the solid state. IV. Study on reduced-pressure mixing for practical use of amorphous mixtures of flufenamic acid.
PubMed:
Physical and chemical changes of medicinals in mixtures with adsorbents in the solid state. III. Determination of vapor pressure of solid drugs by steam distillation.
PubMed:
Physical and chemical changes of medicinals in mixtures with adsorbents in the solid state. II. Application of reduced pressure treatment for the improvement of dissolution of flufenamic acid.
PubMed:
Formulation and stability of diazepam suspension compounded from tablets.
PubMed:
[Effect of antacids on mineral metabolism in persons with healthy kidneys. Double-blind study using an antacid containing magnesium aluminum silicate hydrate].
PubMed:
Influence of viscosity on absorption from nitrofurantoin suspensions.
PubMed:
[Azapropazone plasma levels under simultaneous treatment with an antacid or laxative].
PubMed:
The effect of attapulgite and charcoal on enterotoxicity of Vibrio cholerae and Escherichia coli enterotoxins in rabbits.
PubMed:
Correlation of absorption of sulfamethazine boluses with dissolution using a new dissolution apparatus for veterinary tablets.
PubMed:
Benzoyl peroxide gel in acne therapy.
PubMed:
Influence of monovalent and divalent electrolytes on sorption of neomycin sulfate to attapulgite and montmorillonite clays.