methylbenzethonium chloride
Identification
| Name | methylbenzethonium chloride |
| CAS Number | 25155-18-4 |
| EINECS | 246-675-7 |
| FDA UNII | 4XKK0M5H9M |
| Molecular Formula | C28 H44 Cl N O2 |
| Molecular Weight | 462.11608000 |
| MDL Number | MFCD00011821 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| Soluble in | water, 0.1643 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antimicrobial agents |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | antimicrobial, antistatic agents |
| Recommendation for methylbenzethonium chloride usage levels up to | not for fragrance use. |
| Recommendation for methylbenzethonium chloride flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
benzyl-dimethyl-[2-[2-[2-methyl-4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]azanium;chloride
methyl benzethonium chloride
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Identification of specific pluripotent stem cell death--inducing small molecules by chemical screening.
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Interventions for American cutaneous and mucocutaneous leishmaniasis.
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Is paromomycin an effective and safe treatment against cutaneous leishmaniasis? A meta-analysis of 14 randomized controlled trials.
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Interventions for Old World cutaneous leishmaniasis.
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Leishmania major: in vitro and in vivo anti-leishmanial activity of paromomycin ointment (Leshcutan) combined with the immunomodulator Imiquimod.
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Randomized, controlled, double-blind trial of topical treatment of cutaneous leishmaniasis with paromomycin plus methylbenzethonium chloride ointment in Guatemala.
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Occupational allergic contact dermatitis from alkylammonium amidobenzoate.
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Topical paromomycin/methylbenzethonium chloride plus parenteral meglumine antimonate as treatment of American cutaneous leishmaniasis: controlled study.
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Successful topical treatment of murine cutaneous leishmaniasis with a combination of paromomycin (Aminosidine) and gentamicin.
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Topical paromomycin/methylbenzethonium chloride plus parenteral meglumine antimonate as treatment for American cutaneous leishmaniasis: controlled study.
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Human leishmaniasis: clinical, diagnostic, and chemotherapeutic developments in the last 10 years.
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Successful treatment of New World cutaneous leishmaniasis with a combination of topical paromomycin/methylbenzethonium chloride and injectable meglumine antimonate.
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[Successful topical treatment of chronic cutaneous leishmaniasis with paromomycin sulfate (15%) and methylbenzethonium chloride (12%)].
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Topical treatment of American cutaneous leishmaniasis with paramomycin and methylbenzethonium chloride: a clinical study under field conditions in Ecuador.
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Topical treatment of New World cutaneous leishmaniasis in Belize: a clinical study.
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Topical treatment of cutaneous leishmaniasis in Belize: in vitro and in vivo studies with Leishmania mexicana.
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Leishmania major: bacterial contamination of cutaneous lesions in experimental animals.
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Topical treatment of Old World cutaneous leishmaniasis caused by Leishmania major: a double-blind control study.
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Leishmania major: resistance of promastigotes to paromomycin, and susceptibility of amastigotes to paromomycin-methylbenzethonium chloride ointment.
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Studies on the topical treatment of experimental cutaneous leishmaniasis: the therapeutic effect of methyl benzethonium chloride and the aminoglycosides, gentamicin and paromomycin.
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Leishmania major: histopathological responses before and after topical treatment in experimental animals.
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Leishmania aethiopica: topical treatment with paromomycin and methylbenzethonium chloride ointment.
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Topical treatment of New and Old World cutaneous leishmaniasis in experimental animals.
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Leishmania major: antileishmanial activity of methylbenzethonium chloride.
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Topical treatment of cutaneous leishmaniasis.
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Protection of guinea pigs against cutaneous leishmaniasis by combined infection and chemotherapy.
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Topical treatment of recurrent cutaneous leishmaniasis with ointment containing paromomycin and methylbenzethonium chloride.
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Development of topical treatment for cutaneous leishmaniasis caused by Leishmania major in experimental animals.
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Studies on the local treatment of wounds for the prevention of rabies.
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The prevention and treatment of seborrhea capitis with an antibacterial emulsion containing methylbenzethonium chloride.
PubMed:
ADDITIONAL uses of methylbenzethonium chloride.
PubMed:
Methylbenzethonium chloride in the care of skin of infants and children.
PubMed:
NEW and nonofficial remedies; methylbenzethonium chloride.