picramic acid
4,6-dinitro-2-aminophenol
Identification
| Name | picramic acid |
| IUPAC | 2-amino-4,6-dinitrophenol |
| CAS Number | 96-91-3 |
| EINECS | 202-544-6 |
| FDA UNII | 5VDQ7GK8L3 |
| Molecular Formula | C6 H5 N3 O5 |
| Molecular Weight | 199.12285000 |
| MDL Number | MFCD00070534 |
| Nikkaji Number | J4.727I |
| Beilstein | 0989416 |
| XlogP3 | 0.90 (est) |
Regulatory
Physical Properties
| Appearance | dark red needles or prisms (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 169.00 °C. @ 760.00 mm Hg |
| Boiling Point | 386.30 °C. @ 760.00 mm Hg (est) |
| Flash Point | 370.00 °F. TCC ( 187.50 °C. ) (est) |
| logP (o/w) | 0.930 |
| Soluble in | water, 1400 mg/L @ 22 °C (exp) |
Cosmetic Information
| CosIng | ['cosmetic data2', 'cosmetic data'] |
| Cosmetic Uses | hair dyeing agents |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intravenous-dog LDLo 150 mg/kg |
| Dermal Toxicity | subcutaneous-rat LDLo 2100 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | hair dyeing agents |
| Recommendation for picramic acid usage levels up to | not for fragrance use. |
| Recommendation for picramic acid flavor usage levels up to | not for flavor use. |
Potential Uses
Natural Occurrence
Synonyms
1-
amino-2-hydroxy-3,5-dinitrobenzene
2-
amino-4,6-dinitrophenol
2-
amino-4,6-dinitrophenol (c.i. 76540)
c.i. 76540
C.I. oxidation base 21
ci 76540
CI oxidation base 21
4,6-
dinitro-2-amino phenol
4,6-
dinitro-2-aminophenol
fourrine 4R
fourrine 93
furro 4R
2-
hydroxy-3,5-dinitroaniline
oxidation base 21
phenol, 2-amino-4,6-dinitro-
picraminic acid
zoba 4R
PubMed:
[Analysis of picric acid and picramic acid in water samples by ultra performance hydrophilic interaction chromatography-tandem mass spectrometry].
PubMed:
Amended safety assessment of sodium picramate and picramic acid.
PubMed:
Tissue distribution and elimination of N-methyl-N-2,4,6-tetranitroaniline (tetryl) in rats.
PubMed:
Environmental process descriptors for TNT, TNT-related compounds and picric acid in marine sediment slurries.
PubMed:
Fate and effects of picric acid and 2,6-DNT in marine environments: toxicity of degradation products.
PubMed:
Spectrophotometric determination of flucloxacillin in pharmaceutical preparations using some nitrophenols as a complexing agent.
PubMed:
Analysis of polynitrophenols and hexyl by liquid chromatography-mass spectrometry using atmospheric pressure ionisation methods and a volatile ion-pairing reagent.
PubMed:
Acute toxicity, distribution, and metabolism of 2,4,6-trinitrophenol (picric acid) in Fischer 344 rats.
PubMed:
Effect of glucose upon alkaline picrate: a Jaffé interference.
PubMed:
Uptake, elimination, and metabolism of 14C-picric acid and 14C-picramic acid in the American oyster (Crassostrea virginica).
PubMed:
Bioconcentration and metabolism of picric acid (2,4,6-trinitrophenol) and picramic acid (2-amino-4,6-dinitrophenol) in rainbow trout Salmo gairdneri.
PubMed:
Conversion of 2,4,6-trinitrophenol to a mutagen by Pseudomonas aeruginosa.
PubMed:
The effect of 2,4-dinitrophenol and related compounds on bile secretion.
PubMed:
[Urinary excretion of picric acid, picramic acid and urinary sulfates in experimental tetryl poisoning].