chloridazon

5-amino-4-chloro-2-phenylpyridazinone

CAS: 1698-60-8 C10 H8 Cl N3 O MW: 221.64596000

Identification

Namechloridazon
CAS Number1698-60-8
EINECS216-920-2
FDA UNII26X5RK7X7W
Molecular FormulaC10 H8 Cl N3 O
Molecular Weight221.64596000
MDL NumberMFCD00055402
Nikkaji NumberJ1.775B
Beilstein0397241

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 205.00 °C. @ 760.00 mm Hg
logP (o/w) 1.140
Soluble in water, 400 mg/L @ 20 °C (exp)

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-guinea pig LD50 493 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 1205 mg/kg
Inhalation Toxicityinhalation-rat LC50 > 30800 mg/m3/4

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for chloridazon usage levels up tonot for fragrance use.
Recommendation for chloridazon flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

5- amino-4-chloro-2-phenyl-3-pyridazinone 5- amino-4-chloro-2-phenylpyridazin-3-one 5- amino-4-chloro-2-phenylpyridazin-3(2H)-one 5- amino-4-chloro-2-phenylpyridazinone 5- amino-4-chloro-2,3-dihydro-3-oxo-2-phenylpyridazine BAS 1191611 BAS 13033 burex chloridazone clorizol curbetan 1- fenyl-4-amino-5-chlor-6-pyridazinon phenosane 1- phenyl-4-amino-5-chloropyridaz-6-one 1- phenyl-4-amino-5-chloropyridazin-6-one 1- phenyl-4-amino-5-chlorpyridaz-6-one 1- phenyl-4-amino-5-chlorpyridazon-(6) pyramin RB pyramine pyrazon pyrazone pyrazonl 3(2H)- pyridazinone, 5-amino-4-chloro-2-phenyl- suzon PubMed: Assessment of the genotoxic potential along the Danube River by application of the comet assay on haemocytes of freshwater mussels: The Joint Danube Survey 3. PubMed: Various effects of the photosystem II--inhibiting herbicides on 5-n-alkylresorcinol accumulation in rye seedlings. PubMed: Induction time of Fe-SOD synthesis and activity determine different tolerance of two Desmodesmus (green algae) strains to chloridazon: a study with synchronized cultures. PubMed: Can damselfly larvae (Ischnura elegans) be used as bioindicators of sublethal effects of environmental contamination? PubMed: Sorption of polar herbicides and herbicide metabolites by biochar-amended soil. PubMed: Bentonite and anthracite in alginate-based controlled release formulations to reduce leaching of chloridazon and metribuzin in a calcareous soil. PubMed: Liquid-solid sample preparation followed by headspace solid-phase microextraction determination of multiclass pesticides in soil. PubMed: Destruction of halogen-containing pesticides by means of detonation combustion. PubMed: Phytotoxicity and antioxidative enzymes of green microalga (Desmodesmus subspicatus) and duckweed (Lemna minor) exposed to herbicides MCPA, chloridazon and their mixtures. PubMed: Reduction of matrix effects and improvement of sensitivity during determination of two chloridazon degradation products in aqueous matrices by using UPLC-ESI-MS/MS. PubMed: Non-targeted analysis of wastewater treatment plant effluents by high performance liquid chromatography-time slice-solid phase extraction-nuclear magnetic resonance/time-of-flight-mass spectrometry. PubMed: Studies on the photo-catalytic activity of semiconductor nanostructures and their gold core-shell on the photodegradation of malathion. PubMed: Time- and dose-dependent induction of HSP70 in Lemna minor exposed to different environmental stressors. PubMed: Phenylobacterium muchangponense sp. nov., isolated from beach soil, and emended description of the genus Phenylobacterium. PubMed: The experimental and theoretical QM/MM study of interaction of chloridazon herbicide with ds-DNA. PubMed: Development of analytical strategies using U-HPLC-MS/MS and LC-ToF-MS for the quantification of micropollutants in marine organisms. PubMed: Assessing exposure to transformation products of soil-applied organic contaminants in surface water: comparison of model predictions and field data. PubMed: Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground water. PubMed: Prevention of chloridazon and metribuzin pollution using lignin-based formulations. PubMed: A direct LC/MS/MS method for the determination of ciclopirox penetration across human nail plate in in vitro penetration studies. PubMed: Assessment of heavy metal and pesticide levels in soil and plant products from agricultural area of Belgrade, Serbia. PubMed: Environmental occurrence and degradation of the herbicide n-chloridazon. PubMed: Adsorption of chloridazon from aqueous solution on modified kerolite-rich materials. PubMed: Modifying sorbents in controlled release formulations to prevent herbicides pollution. PubMed: Metamitron-resistant Chenopodium album from sugar beet: cross-resistance profile. PubMed: Individual and combined effect of anthracene, cadmium, and chloridazone on growth and activity of SOD izoformes in three Scenedesmus species. PubMed: [A new species of the genus Phenylobacterium for the degradation of LAS (linear alkylbenzene sulfonate)]. PubMed: Adsorption of chloridazon from aqueous solution on heat and acid treated sepiolites. PubMed: Wet deposition of pesticides and nitrophenols at two sites in Denmark: measurements and contributions from regional sources. PubMed: Effects of addition of straw, chitin and manure to new or recycled biofilters on their pesticides retention and degradation properties. PubMed: Electrochemical reduction of chloridazon at mercury electrodes, and its analytical application. PubMed: A study on the behaviour of pesticides and their transformation products in the Scheldt estuary using liquid chromatography-electrospray tandem mass spectrometry. PubMed: Effect of chloridazone on the animal organism. PubMed: Ultra-trace-level determination of polar pesticides and their transformation products in surface and estuarine water samples using column liquid chromatography-electrospray tandem mass spectrometry. PubMed: The organochlorine herbicide chloridazon interacts with cell membranes. PubMed: Cytogenetic effects of the herbicide chloridazon in cultured sheep lymphocytes. PubMed: Acute oral toxicity of the herbicide BUREX EKO in pheasants. PubMed: Rapid extraction and capillary gas chromatography for diazine herbicides in human body fluids. PubMed: Dibenzofuran 4,4a-dioxygenase from Sphingomonas sp. strain RW1: angular dioxygenation by a three-component enzyme system. PubMed: [Phenazon metabolism in children with liver diseases]. PubMed: [Effectiveness of introducing individual protection measures for workers in the phenazone industry]. PubMed: Acute toxicity of pesticides in adult and weanling rats. PubMed: [Physical, chemical and biological study of dust from large-scale pig farms]. PubMed: [Occurrence of drug reactions]. PubMed: [Experimental study of the gonadotoxic action of 1-phenyl-4-amino-5-chloropyridazole-6]. PubMed: Purification of arogenate dehydrogenase from Phenylobacterium immobile. PubMed: [Decomposition and stabilization of drugs. XX. Photodecomposition and stabilization of dipyridamol]. PubMed: Chloridazon-catechol dioxygenases, a distinct group of meta-cleaving enzymes. PubMed: The lipopolysaccharide of a chloridazon-degrading bacterium. PubMed: Serological studies on chloridazon-degrading bacteria. PubMed: Allergic contact dermatitis to chloridazon. PubMed: A novel non-heme iron-containing dioxygenase. Chloridazon-catechol dioxygenase from Phenylobacterium immobilis DSM 1986. PubMed: Determination of pyrazon residues in water by reversed phase high performance liquid chromatography. PubMed: Influence of pyramin and venzar on some metabolic products of Azotobacter chroococcum. PubMed: Bacterial degradation of aminopyrine. PubMed: [Degradation of L-phenylalanine and of aromatic carboxylic acids by chloridazon-degrading bacteria. Combination of side chain degradation and dioxygenase pathway]. PubMed: Bacterial conversion of phenylalanine and aromatic carboxylic acids into dihydrodiols. PubMed: Acute toxicity testing of some herbicides-, alkaloids-, and antibiotics-metabolizing soil bacteria in the rat. PubMed: Herbicidal effect on some metabolic processes of Azotobacter chroococcum. PubMed: Interactions of Mycelia sterilia G-1 with venzar and pyramin. PubMed: Herbicidal treatments for control of Papaver somniferum L. PubMed: Influence of selected pesticides on the microbial degradation of 14C-triallate and 14C-diallate in soil. PubMed: [Degradation and biosynthesis of L-phenylalanine by chloridazon-degrading bacteria]. PubMed: [Preparation of a chloridazon metabolite by use of immobilized chloridazon-dihydrodiol dehydrogenase. Some properties of the immobilized enzyme]. PubMed: [Purification and properties of two chloridazondihydrodiol dehydrogenases from chloridazon degrading bacteria]. PubMed: [What does conservative therapy of "idiopathic" facial paresis accomplish?]. PubMed: [Degradation of antipyrin by pyrazon-degrading bacteria (author's transl)]. PubMed: [Catechol 2,3-dioxygenase from pyrazon-degrading bacteria (author's transl)]. PubMed: Purification and properties of pyrazon dioxygenase from pyrazon-degrading bacteria. PubMed: [Enzymatic formationof 4-hydroxy-2-oxovalerate using pyrazon-degrading bacteria (author's transl)]. PubMed: [Enzymatic formation of a cis,cis-muconic acid derivative using pyrazon-degrading bacteria (author's transl)]. PubMed: Fate of pyrazon in a model ecosystem. PubMed: Bacterial hydroxylation of pyrazon compounds. PubMed: [Isolation and characterization of bacteria, growing on pyrazon]. PubMed: [Not Available]. PubMed: THE ROLE OF PYRAZON IN REACTIONS IN TUBERCULOID LEPROSY. PubMed: A study of the yeast fermentation method for the determination of thiamine and pyramin. PubMed: Relation between urinary excretion of thiamine and pyramin (the pyrimidine-like component of thiamine). PubMed: The urinary excretion of thiamine, pyramin (the pyrimidine-like component of thiamine) and riboflavin by man in semistarvation.