shark liver oil

fats and glyceridic oils, shark-liver

CAS: 68990-63-6

Identification

Nameshark liver oil
CAS Number68990-63-6
FDA UNII4B24275HEU

Regulatory

Physical Properties

Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-mouse LD50 > 30000 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 > 30000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for shark liver oil usage levels up tonot for fragrance use.
Recommendation for shark liver oil flavor usage levels up tonot for flavor use.

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Potential Uses

emollients

Natural Occurrence

found in nature

Synonyms

fats and glyceridic oils, shark-liver oils, shark-liver PubMed: Jurassic surgery and immunity enhancement by alkyglycerols of shark liver oil. PubMed: Alkylglycerols modulate the proliferation and differentiation of non-specific agonist and specific antigen-stimulated splenic lymphocytes. PubMed: [Nonspecific immunomodulation in obstetrics and gynecology with Ecomer preliminary report]. PubMed: Antitumor and anti-cachectic effects of shark liver oil and fish oil: comparison between independent or associative chronic supplementation in Walker 256 tumor-bearing rats. PubMed: Oral administration of alkylglycerols differentially modulates high-fat diet-induced obesity and insulin resistance in mice. PubMed: [Anti-tumor activity of 1-O-alkylglycerols--the main component of shark liver oil]. PubMed: Discrimination against diacylglycerol ethers in lipase-catalysed ethanolysis of shark liver oil. PubMed:  Shark liver oil: hidden dangers. PubMed: Biological importance and applications of squalene and squalane. PubMed: Chronic supplementation with shark liver oil for reducing tumor growth and cachexia in walker 256 tumor-bearing rats. PubMed: Walker-256 tumor growth is inhibited by the independent or associative chronic ingestion of shark liver and fish oil: a response linked by the increment of peritoneal macrophages nitrite production in Wistar rats. PubMed: An update on the therapeutic role of alkylglycerols. PubMed: Squalene as novel food factor. PubMed: Multiple beneficial health effects of natural alkylglycerols from shark liver oil. PubMed: Vaccination, squalene and anti-squalene antibodies: facts or fiction? PubMed: Which alkylglycerols from shark liver oil have anti-tumour activities? PubMed: Effect of chronic supplementation with shark liver oil on immune responses of exercise-trained rats. PubMed: Acute and repeated dose (28 days) oral safety studies of an alkoxyglycerol extract from shark liver oil in rats. PubMed: The effect of shark liver oil on the tumor infiltrating lymphocytes and cytokine pattern in mice. PubMed: Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology. PubMed: [The clinical and experimental research of metabolic effects of shark liver oil]. PubMed: Supercritical carbon dioxide fractionation of nonesterified alkoxyglycerols obtained from shark liver oil. PubMed: [Shark liver oil as a supporting therapy in atopic dermatitis]. PubMed: The influence of shark liver oils on normal and transformed mammalian cells in culture. PubMed: Occurrence of polybrominated diphenyl ethers and polychlorinated biphenyls in shark liver oil supplements. PubMed: [Health properties of shark oil]. PubMed: 1 -O-alkyl-2-(omega-oxo)acyl-sn-glycerols from shark oil and human milk fat are potential precursors of PAF mimics and GHB. PubMed: [Biological action and clinical application of shark liver oil]. PubMed: A study on fatty acid composition of fish oil from two marine fish, Eusphyra blochii and Carcharhinus bleekeri. PubMed: Tetra- and tribromophenoxyanisoles in marine samples from Oceania. PubMed: Humoral defence improvement and haematopoiesis stimulation in sows and offspring by oral supply of shark-liver oil to mothers during gestation and lactation. PubMed: [Effect of high doses of shark liver oil supplementation on T cell polarization and peripheral blood polymorphonuclear cell function]. PubMed: Oral intake of shark liver oil modifies lipid composition and improves motility and velocity of boar sperm. PubMed: Natural alkylglycerols restrain growth and metastasis of grafted tumors in mice. PubMed: Natural 1-O-alkylglycerols reduce platelet-activating factor-induced release of [3H]-serotonin in rabbit platelets. PubMed: Cytostatic and cytotoxic effects of alkylglycerols (Ecomer). PubMed: Inhibitory effect of Greenland shark liver oil combined with squalen and arctic birch ashes on angiogenesis and L-1 sarcoma growth in Balb/c mice. PubMed: [Modification of innate immunity in humans by active components of shark liver oil]. PubMed: Effect of squalene and shark liver oil on serum cholesterol level in hamsters. PubMed: The antipromoting effect of alkyloglycerols from shark liver oil. PubMed: [The assessment of the effectiveness of the shark liver oil in recurrent aphthous stomatitis treatment: clinical and immunological studies]. PubMed: The synergistic effect of lactic acid bacteria and alkylglycerols on humoral immunity in mice. PubMed: [Studies on the genotoxic effects of crude liver oils from 3 species of Mediterranean sharks by means of in vitro micronucleus test using human lymphocytes]. PubMed: Inhibitory effect of shark liver oil on cutaneous angiogenesis induced in Balb/c mice by syngeneic sarcoma L-1, human urinary bladder and human kidney tumour cells. PubMed: Shark liver oil-induced lipoid pneumonia in pigs: correlation of thin-section CT and histopathologic findings. PubMed: Exogenous lipoid pneumonia: high-resolution CT findings. PubMed: Some biological actions of alkylglycerols from shark liver oil. PubMed: Diets enriched in menhaden fish oil, seal oil, or shark liver oil have distinct effects on the lipid and fatty-acid composition of guinea pig heart. PubMed: Modulation of platelet-activating-factor production by incorporation of naturally occurring 1-O-alkylglycerols in phospholipids of human leukemic monocyte-like THP-1 cells. PubMed: Shark oil pneumonia. An overlooked entity. PubMed: [Shark liver oil (alkoxyglycerol) and cancer treatment]. PubMed: [The National Board of Health and Welfare prohibits Ecomer. Shark liver oil is suspected of adverse effects]. PubMed: Carcinogenicity of diethylnitrosamine in vitamin-A-deficient mice. PubMed: Stimulation of immune reactivity by methoxy-substituted glycerol ethers incorporated into the feed. PubMed: 1-O-(2-hydroxyalkyl)glycerols isolated from Greenland shark liver oil. PubMed: Fortification of shark liver oil with iron. PubMed: Separation of neutral lipids of shark liver by "dry-column" chromatography. PubMed: Basking shark liver oil sterols and glyceryl ethers. UCLA-12-686. PubMed: Gas chromatographic-mass spectrometric analysis of isoprenoid hydrocarbons and fatty acids in shark liver oil products. PubMed: Effect of shark liver oil on plasma cholesterol and lipoprotein pattern in man. PubMed: Biological and chemical estimation of vitamin D in shark-liver oil. PubMed: [Shark liver oil; medicoindustrial importance]. PubMed: Deodorization of shark liver oil. PubMed: Note on a color reaction for shark-liver oil. PubMed: The spectrophotometric examination of shark liver oils and products derived from them. PubMed: Effect of storage and acidity on the protection of vitamin A in shark liver oil by antioxidants. PubMed: Local therapy of shark-liver oil in nyctalopia. PubMed: Australian shark liver oil. PubMed: Chemical composition of shark liver oil. PubMed: The utilisation of by-products of the shark liver oil industry. PubMed: Studies on the destruction of vitamin A in shark-liver oil; some factors affecting the stability. PubMed: Studies on the destruction of vitamin A in shark-liver oil; effect of some anti-oxidants on the stabilisation of vitamin A. PubMed: Studies on the destruction of vitamin A in shark-liver oil; catalytic activity of metals. PubMed: Studies on the destruction of vitamin A in shark-liver oil; relation between vitamin A destruction and peroxide number.