simethicone
a-(trimethylsilyl)-omega-methylpoly(oxy(dimethylsilylene)), mixture with silicon dioxide
Identification
| Name | simethicone |
| IUPAC | dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane |
| CAS Number | 8050-81-5 |
| FDA UNII | Search |
| Molecular Formula | C6 H18 O4 Si3 |
| Molecular Weight | 238.46216000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 96.50 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 49.600000 mmHg @ 25.00 °C. (est) |
| Flash Point | 43.00 °F. TCC ( 6.30 °C. ) (est) |
| logP (o/w) | 3.404 (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antifoaming agents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intravenous-dog LD50 900 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | antifoaming, emollient agents |
| Recommendation for simethicone usage levels up to | not for fragrance use. |
| Recommendation for simethicone flavor usage levels up to | not for flavor use. |
American International Chemical, Inc.
Consistent sources
North American supplier for globally sourced ingredients.
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Potential Uses
Natural Occurrence
Synonyms
antifoam A
dc
antifoam A
asidopan plus
DC antifoam A
di-gel
dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane
gas-X
gelusil
kudrox
maalox hrf
maalox plus
mylanta
mylicon infant's drops
phazyme
riopan plus
rioplus
sentry simethicone
silicone antifoam agent s 184
silicone antifoam emulsions se 6 and se 9
simeco
alpha-(
trimethyl silyl)-omega-methyl poly(oxy(dimethyl silylene)) mixture with silicon dioxide
a-(
trimethylsilyl)-omega-methylpoly(oxy(dimethylsilylene)), mixture with silicon dioxide
wydrate plus
PubMed:
The early administration of Lactobacillus reuteri DSM 17938 controls regurgitation episodes in full-term breastfed infants.
PubMed:
Acute diarrhea.
PubMed:
[Ideas about registration for breast implants].
PubMed:
[Values of the micronucleus test on animal epithelial cells exposed to titanium dioxide].
PubMed:
Colic in infants.
PubMed:
First identification of O,S-diethyl Thiocarbonate in Indian Cress absolute and odor evaluation of its synthesized homologues by GC-sniffing.
PubMed:
Bowel preparations for capsule endoscopy: a comparison between simethicone and magnesium citrate.
PubMed:
Clinical pharmacokinetics and gastrointestinal tolerability of a novel extended-release microsphere formulation of azithromycin.
PubMed:
Infantile colic.
PubMed:
Infantile colic.
PubMed:
Infantile colic.
PubMed:
The radiological management of oesophageal food bolus obstruction using a gas-forming agent and barium.
PubMed:
Use of a decision-analytic model to support the use of a new oral US contrast agent in patients with abdominal pain.
PubMed:
Effectiveness of treatments for infantile colic: systematic review.
PubMed:
[Management of infantile colics].
PubMed:
The use of effervescent agents in the small bowel meal examination.
PubMed:
Causes of non-medication-induced nasogastric tube occlusion.
PubMed:
Management of infantile colic.
PubMed:
The effect of an antacid and food on the absorption of cimetidine and ranitidine.
PubMed:
Substances that interfere with guaiac card tests: implications for gastric aspirate testing.
PubMed:
The GI drug column. The ACG committee on FDA related matters.