sodium laureth sulfate
poly(oxy-1,2-ethanediyl), a-sulfo-omega-(dodecyloxy)-, sodium salt
Identification
| Name | sodium laureth sulfate |
| IUPAC | sodium;2-dodecoxyethyl sulfate |
| CAS Number | 9004-82-4 |
| FDA UNII | 410Q7WN1BX |
| Molecular Formula | (C2 H4 O)mult-C12 H26 O4 S.Na |
| Nikkaji Number | J78.126F |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | FCN 54 |
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w) | 5.405 (est) |
| Soluble in | water, 187.3 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | cleansing agents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-rat LD50 1600 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | emulsifiers, surfactants |
| Recommendation for sodium laureth sulfate usage levels up to | not for fragrance use. |
| Recommendation for sodium laureth sulfate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
avirol 100E
cycloryl NA
2-(
dodecyloxy)ethanol hydrogen sulfate sodium salt
2-(
dodecyloxy)ethyl sodium sulfate
emal 170J
emal 20C
emal 227E
emal 228D/JM
emal 270D
emal 270E
emal 270J
emal 327
emal E-27C
empimin KSN
ethanol, 2-(dodecyloxy)-, hydrogen sulfate, sodium salt (1:1)
etoxon EPA
maprofix ES
poly(oxy-1,2-ethanediyl), a-sulfo-omega-(dodecyloxy)-, sodium salt
poly(oxyethylene) lauryl ether sulfate sodium salt
sodium 2-(dodecyloxy)ethyl sulfate
sodium lauryl ether sulfate
sodium lauryl ether sulphate
sodium polyethoxyethyl dodecyl sulfate
sodium;2-dodecoxyethyl sulfate
PubMed:
Effects of temperature, surfactants and skin location on the dermal penetration of haloacetonitriles and chloral hydrate.
PubMed:
Growth inhibition and stimulation of Shewanella oneidensis MR-1 by surfactants and calcium polysulfide.
PubMed:
Foam consolidation and drainage.
PubMed:
Detergents modify proteinase K resistance of PrP Sc in different transmissible spongiform encephalopathies (TSEs).
PubMed:
The effect of spray drying on the compaction properties of hypromellose acetate succinate.
PubMed:
Final report of the amended safety assessment of sodium laureth sulfate and related salts of sulfated ethoxylated alcohols.
PubMed:
Interlaboratory studies with a proposed patch test design to evaluate the irritation potential of surfactants.
PubMed:
Quantitative analysis of surfactant deposits on human skin by liquid chromatography/electrospray ionisation tandem mass spectrometry.
PubMed:
Telethermography: an objective method for evaluating patch test reactions.
PubMed:
Hair breakage--how to measure and counteract.
PubMed:
Characterization of sodium laureth sulfate by reversed-phase liquid chromatography with evaporative light scattering detection and 1H nuclear magnetic resonance spectroscopy.
PubMed:
Simultaneous treatment of graywater and waste gas in a biological trickling filter.
PubMed:
Separation and quantitative analysis of alkyl sulfate ethoxymers by HPLC.
PubMed:
Evaulation of irritation potential of surfactant mixtures.
PubMed:
Discovery of synergistic permeation enhancers for oral drug delivery.
PubMed:
The differences in human cumulative irritation responses to positive and negative irritant controls from three geographical locations.
PubMed:
Determination of the substantivity of emollients to human hair.
PubMed:
[Bovine udder skin (BUS): testing of skin compatibility and skin protection].
PubMed:
Synergistic sphere-to-rod micelle transition in mixed solutions of sodium dodecyl sulfate and cocoamidopropyl betaine.
PubMed:
Effect of pH-sodium lauryl sulfate combination on solubilization of PG-300995 (an anti-HIV agent): a technical note.
PubMed:
Simultaneous quantification of poly-dispersed anionic, amphoteric and nonionic surfactants in simulated wastewater samples using C18 high-performance liquid chromatography-quadrupole ion-trap mass spectrometry.
PubMed:
A novel role for vernix caseosa as a skin cleanser.
PubMed:
Response of graywater recycling systems based on hydroponic plant growth to three classes of surfactants.
PubMed:
Discovery of transdermal penetration enhancers by high-throughput screening.
PubMed:
Profile of irritant patch testing with detergents: sodium lauryl sulfate, sodium laureth sulfate and alkyl polyglucoside.
PubMed:
Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES).
PubMed:
Determination of anionic surfactants during wastewater recycling process by ion pair chromatography with suppressed conductivity detection.
PubMed:
An open assay model to induce subclincal non-erythematous irritation.