sodium ricinoleate
sodium (R)-12-hydroxyoleate
Identification
| Name | sodium ricinoleate |
| IUPAC | sodium;(Z)-12-hydroxyoctadec-9-enoate |
| CAS Number | 5323-95-5 |
| EINECS | 226-191-2 |
| FDA UNII | OOO64813BX |
| Molecular Formula | C18 H33 Na O3 |
| Molecular Weight | 320.44837928 |
| MDL Number | MFCD00050760 |
| Nikkaji Number | J191.732C |
Regulatory
| FDA Mainterm (IAUFC) | 5323-95-5 ; SODIUM RICINOLEATE |
Physical Properties
| Appearance | white or slightly yellow powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 416.40 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000000 mmHg @ 25.00 °C. (est) |
| Flash Point | 428.00 °F. TCC ( 219.80 °C. ) (est) |
| logP (o/w) | 5.701 (est) |
| Soluble in | water, 279.4 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | cleansing agents |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | unreported-mouse LDLo 400 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for sodium ricinoleate usage levels up to | not for fragrance use. |
| Recommendation for sodium ricinoleate flavor usage levels up to | not for flavor use. |
Potential Uses
Natural Occurrence
Synonyms
12-
hydroxy-9-octadecenoic acid, sodium salt
9-
octadecenoic acid, 12-hydroxy-, monosodium salt, (9Z,12R)-
9-
octadecenoic acid, 12-hydroxy-, monosodium salt, (R-(Z))- (9CI)
9-
octadecenoic acid, 12-hydroxy-, sodium salt
ricinoleic acid sodium salt
ricinoleic acid, sodium salt
sodium (R)-12-hydroxyoleate
sodium ricinolate
sodium;(Z)-12-hydroxyoctadec-9-enoate
PubMed:
Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombus model.
PubMed:
Ultrasound-enhanced thrombolytic effect of tissue plasminogen activator-loaded echogenic liposomes in an in vivo rabbit aorta thrombus model--brief report.
PubMed:
Final report on the safety assessment of Ricinus Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Glyceryl Ricinoleate, Glyceryl Ricinoleate SE, Ricinoleic Acid, Potassium Ricinoleate, Sodium Ricinoleate, Zinc Ricinoleate, Cetyl Ricinoleate, Ethyl Ricinoleate, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate, and Octyldodecyl Ricinoleate.
PubMed:
Toxicology and pharmacology of sodium ricinoleate.
PubMed:
A comparison of peripheral and central effects of clonidine on rat intestinal transit.
PubMed:
Involvement of the enteric nervous system in the intestinal secretion induced by sodium deoxycholate and sodium ricinoleate.
PubMed:
Surfactants selectively ablate enteric neurons of the rat jejunum.
PubMed:
The effects of deoxycholic and ricinoleic acid on the isolated circular muscle of the cat colon are modified by leucine-enkephalin.
PubMed:
Activity of sodium ricinoleate against in vitro plaque.
PubMed:
Effects of antibacterial microenvironment on in vitro plaque formation of Streptococcus mutans as observed by scanning electron microscopy.
PubMed:
Mechanism of inhibition of alanine absorption by Na ricinoleate.
PubMed:
Perfusion of rabbit colon with ricinoleic acid: dose-related mucosal injury, fluid secretion, and increased permeability.
PubMed:
The effects of sodium ricinoleate on small intestinal function and structure.
PubMed:
Ricinoleic acid (castor oil) alters intestinal surface structure. A scanning electronmiscroscopic study.
PubMed:
Inhibitory actions of laxatives on motility and water and electrolyte transport in the gastrointestinal tract.
PubMed:
Circular muscle electromyogram in the cat colon: local effect of sodium ricinoleate.
PubMed:
Diarrhea, castor oil, and sodium ricinoleate: their effect on electric slow waves of the colon.
PubMed:
Fate of sodium ricinoleate after oral administration to white rats.
PubMed:
Fate of sodium ricinoleate after oral administration to white rats.
PubMed:
EXPERIMENTS ON ACTIVE IMMUNIZATION AGAINST EXPERIMENTAL POLIOMYELITIS.
PubMed:
Sodium Ricinoleate: Its Possible Value in the Prevention and Treatment of Peritonitis.
PubMed:
The Effect of Sodium Ricinoleate on the Gonococcus.
PubMed:
A COMPARATIVE STUDY OF THE ACTION OF SODIUM RICINOLEATE UPON BACTERIA.