Identification

Namebutyl butyrate
IUPACbutyl butanoate
CAS Number109-21-7
EINECS203-656-8
FDA UNII1BHV00T1M4
Molecular FormulaC8 H16 O2
Molecular Weight144.21392000
MDL NumberMFCD00009450
Nikkaji NumberJ2.876B
Beilstein1747101
CoE Number268

Regulatory

JECFA Food Flavoring151 butyl butyrate
DG SANTE Food Flavourings09.042 butyl butyrate
FEMA Number2186
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)109-21-7 ; BUTYL BUTYRATE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless clear liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed Yes
Specific Gravity 0.86700 to 0.87100 @ 25.00 °C.
Pounds per Gallon - (est). 7.214 to 7.248
Refractive Index 1.40500 to 1.40700 @ 20.00 °C.
Melting Point 91.50 °C. @ 760.00 mm Hg
Boiling Point 166.00 °C. @ 760.00 mm Hg
Acid Value 1.00 max. KOH/g
Vapor Pressure 1.810000 mmHg @ 25.00 °C.
Vapor Density 4.9 ( Air = 1 )
Flash Point 121.00 °F. TCC ( 49.44 °C. )
logP (o/w) 2.823 (est)
Shelf Life 24.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium
Substantivity 8 hour(s) at 100.00 %
Odor Description
at 100.00 %.
Sweet, fruity, fresh, diffusive and ripe
apple; banana; berry; peach; pear
strongly fruity, estery, green; pineapple-, banana-, raspberry-like
Odor sample from Fritzsche Dodge & Olcott, Inc.
Taste Description
sweet fruity ethereal tropical rummy cherry ripe fruit elderberry fatty
at 40.00 ppm.
sweet fresh fruity fatty

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicityoral-rabbit LD50 9520 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for butyl butyrate usage levels up to8.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)390.00 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum150.00000
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Advanced Biotech. Inc.

Inspired by Nature

A diverse range of products, all meeting our stringent commitment to quality.

View All Website 973-339-6242 info@adv-bio.com

Alfrebro LLC/ Archer Daniels Midland Company

Let's get reacquainted

Building great taste with aroma chemicals, extracts, and distillates

View All Website 513-539-7373 sforbis@alfrebro.com

Augustus Oils Ltd

The Premier Supplier

Augustus Oils Ltd, in harmony with nature - to present it at its best...

View All Website +44 (0)1420 590555 essentials@augustus-oils.ltd.uk

Axxence Aromatic GmbH

We bring nature to your flavour

Dedicated to provide the best possible quality and supply service of natural aroma ingredients.

View All Website +49.2822.68561.0 service@axxence.com

Charkit Chemical Corporation

The Specialty Chemical Specialists

Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.

View All Website 203-299-3220 sales@charkit.com

CJ Latta & Associates, LLC

Extensive Line

Aromatic Chemicals and Organic Acids.

View All Website (630) 240-8079 chiplatta@msn.com

Elan Inc.

Legacy of Innovation

Highest quality natural and synthetic products.

View All Website +86 021 57448053 (Elan Shanghai) dpimentel@elan-chemical.com

Excellentia International

Ingredients by Nature

Exceptional quality and excellence in meeting our customers requirements.

View All Website 732.749.9840 info@excellentiaint.com

H. Interdonati, Inc.

Innovative products

Because your flavors and fragrances are only as good as their source "Since 1952"

View All Website 800 367-6617 flavorplus@hinterdonati.com

FRUTAROM USA INC,

Flavor & Specialty Ingredients

Your preferred partner for flavour and fragrance success.

View All Website +44 (0) 1429 863 222 Sales.IFFIngredients@iff.com

Indukern, S.A. F&F Ingredients Division

Commitment to quality

Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients.

View All Website +34 93 506 91 00 info@indukern.es

Jiangyin Healthway International Trade Co., Ltd

Independent Ingredients Supplier

We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.

View All Website 86-510-86023169 info@healthwaychem.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

Meeting customers increasing demands at home as well as abroad.

View All Website 908-359-9000 sales@mu-intel.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

Innovation and commitment in the name of excellence.

View All Website +39 039.685.6262

Odowell Co.,ltd

Fulfilling Demand

Product quality and consistency.

View All Website +86-21-56410859 info@odowell.com

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

PerfumersWorld Ltd.

feeeel... the smell!

The one-stop resource for the creative perfumer.

View All Website +66(0)2-99-800-80 pwenquiries@perfumersworld.com

Sigma-Aldrich

Complete Supply Chain

The perfect blend of products and services that bring your creativity to life.

View All Website 800-244-1173 ff@sial.com

Sunaux International

Buy With Confidence

We have industry leading processes and procedures to ensure nothing but the most reliable product.

View All Website 0512-57995626 johnjft@sunaux.com

Taytonn ASCC Pte Ltd

Supplying Asia Pacific

We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.

View All Website + 65 - 6861 8113 info@taytonnascc.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

The Lermond Company

Your Sourcing Resource

The Lermond family has been sourcing raw materials for the flavor and fragrance industry for nearly 7 decades.

View All Website 201-896-3300 info@lermond.com

R C Treatt and Co Ltd

Innovative ingredient solutions

World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.

View All Website +1 863 668 9500 enquiries@treatt.com

Ernesto Ventós S.A.

Leaders in essence

We employ our five senses to do our job well.

View All Website +1 856 226 7501 info@ventos.com

Vigon International

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

View All Website 570-476-6300 sales@vigon.com

WholeChem, LLC

Connecting Innovators To the Building Blocks Of the Universe

Custom manufacturer and distributor of specialty ingredients. We make global local.

View All Website +1 (262) 995.8668 info@wholechem.com

Potential Uses

FR apple FR apricot FR banana FR butter FR butterscotch FR citrus FR fruit juicy fruit FR grape FR green FR mango FR orange FR passion fruit FR pear FR pineapple FR plum FR raspberry FR strawberry FR woodruff

Natural Occurrence

apple fruit PMC apple juice PMC banana fruit berries PMC cheese PMC grape heracleum paphlagonicum czeczott fruit oil turkey @ 0.20% Data honey PMC lavandin oil abrialis @ 0.03% Data lavandin oil grosso @ 0.04% Data mango fruit mushroom PMC orange fruit juice osmanthus absolute @ 0.02% Data passion fruit pear fruit plum fruit soybean strawberry wild strawberry fruit

Synonyms

butanoic acid butyl ester butanoic acid, butyl ester butyl butanoate N- butyl butanoate 1- butyl butyrate N- butyl butyrate nat. butyl butyrate butyl butyrate (natural) butyl butyrate FCC N- butyl butyrate FCC butyl butyrate natural N- butyl butyrate natural butyl butyrate normal FCC butyl butyrate normal natural N- butyl N-butanoate N- butyl N-butyrate butyric acid butyl ester butyric acid N-butyl ester Info: Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.) PubMed: Optimized butyl butyrate synthesis catalyzed by Thermomyces lanuginosus lipase. PubMed: Simultaneous Clostridial fermentation, lipase-catalyzed esterification, and ester extraction to enrich diesel with butyl butyrate. PubMed: Improved production of butyl butyrate with lipase from Thermomyces lanuginosus immobilized on styrene-divinylbenzene beads. PubMed: High-temperature measurements of the reactions of OH with small methyl esters: methyl formate, methyl acetate, methyl propanoate, and methyl butanoate. PubMed: Lipase-catalyzed synthesis of butyl butyrate by alcoholysis in an integrated liquid-vapor system. PubMed: Identification of host fruit volatiles from three mayhaw species (Crataegus series Aestivales) attractive to mayhaw-origin Rhagoletis pomonella flies in the southern United States. PubMed: Identification of fruit volatiles from green hawthorn (Crataegus viridis) and blueberry hawthorn (Crataegus brachyacantha) host plants attractive to different phenotypes of Rhagoletis pomonella flies in the southern United States. PubMed: Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose. PubMed: Rational design of efficient modular cells. PubMed: Volatile fingerprint of Brazilian defective coffee seeds: corroboration of potential marker compounds and identification of new low quality indicators. PubMed: Delivery of floxuridine derivatives to cancer cells by water-soluble organometallic cages. PubMed: Anatomical Variations of Upper Segmental Renal Artery and Clinical Significance. PubMed: Effect of glucosamine conjugation to zinc(II) complexes of a bis-pyrazole ligand: syntheses, characterization and anticancer activity. PubMed: Identification and field evaluation of pear fruit volatiles attractive to the oriental fruit moth, Cydia molesta. PubMed: Pickering emulsions stabilized by surface-modified Fe3O4 nanoparticles. PubMed: Covalent attachment of lipases on glyoxyl-agarose beads: application in fruit flavor and biodiesel synthesis. PubMed: Characterization of plant-derived lactococci on the basis of their volatile compounds profile when grown in milk. PubMed: Does activation of the anti proton, rather than concertedness, determine the stereochemistry of base-catalyzed 1,2-elimination reactions? Anti stereospecificity in E1cB eliminations of β-3-trifluoromethylphenoxy esters, thioesters, and ketones. PubMed: Immobilization of Thermomyces lanuginosus lipase by different techniques on Immobead 150 support: characterization and applications. PubMed: Characterization of an acidic cold-adapted cutinase from Thielavia terrestris and its application in flavor ester synthesis. PubMed: Volatile fragrances associated with flowers mediate host plant alternation of a polyphagous mirid bug. PubMed: Regioselective acylation of disaccharides in tert-butyl alcohol catalyzed by Candida antarctica lipase. PubMed: Baclofen ester and carbamate prodrug candidates: a simultaneous chromatographic assay, resolution optimized with DryLab. PubMed: Nucleophilic addition to 2,3-disubstituted butanal derivatives and their application to natural product synthesis. PubMed: Influence of processing on the volatile profile of strawberry spreads made with isomaltulose. PubMed: Biochemical characterization of a first fungal esterase from Rhizomucor miehei showing high efficiency of ester synthesis. PubMed: Asymmetric synthesis of anti-(2S,3S)- and syn-(2R,3S)-diaminobutanoic acid. PubMed: Comparison of volatile components in Chinese traditional pickled peppers using HS-SPME-GC-MS, GC-O and multivariate analysis. PubMed: Magnetic Pickering emulsions stabilized by Fe3O4 nanoparticles. PubMed: Structural transitions in cholesterol-based wormlike micelles induced by encapsulating alkyl ester oils with varying architecture. PubMed: Evaluation of immobilized lipases on poly-hydroxybutyrate beads to catalyze biodiesel synthesis. PubMed: Rate coefficients for reactions of OH and Cl with esters. PubMed: [Studies on the chemical constituents of rhizoma of Coniogramme japonica]. PubMed: Profiling fruit volatiles in the progeny of a 'Royal Gala' x 'Granny Smith' apple (Malus x domestica) cross. PubMed: Novel syn intramolecular pathway in base-catalyzed 1,2-elimination reactions of beta-acetoxy esters. PubMed: Comparative analysis of the volatile fraction from Annona cherimola Mill. cultivars by solid-phase microextraction and gas chromatography-quadrupole mass spectrometry detection. PubMed: [Changes in amino acid and fatty acid contents as well as activity of some related enzymes in apple fruit during aroma production]. PubMed: Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release. PubMed: Screening of food grade lipases to be used in esterification and interesterification reactions of industrial interest. PubMed: Aroma development during ripening of Fragaria chiloensis fruit and participation of an alcohol acyltransferase (FcAAT1) gene. PubMed: Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents. PubMed: Enzymatic reactions and synthesis of n-butyl caproate: esterification, transesterification and aminolysis using a recombinant lipase from Geobacillus thermoleovorans CCR11. PubMed: Diastereoselective hydroxylation of 6-substituted piperidin-2-ones. An efficient synthesis of (2S,5R)-5-hydroxylysine and related alpha-amino acids. PubMed: Sex pheromone of the mullein bug,Campylomma verbasci (Meyer) (Heteroptera: Miridae). PubMed: Linker-oriented design of binaphthol derivatives for optical resolution using lipase-catalyzed reaction. PubMed: Identification of apple volatiles attractive to the apple maggot,Rhagoletis pomonella. PubMed: A scanning force microscopy study on the motion of single brush-like macromolecules on a silicon substrate induced by coadsorption of small molecules. PubMed: Headspace solid phase microextraction and gas chromatography-olfactometry dilution analysis of young and aged Chinese "Yanghe Daqu" liquors. PubMed: Rapid differentiation of new apple cultivars by headspace solid-phase microextraction in combination with chemometrical data processing. PubMed: Character impact odorants of the apple cultivars Elstar and Cox Orange. PubMed: Assimilation of volatiles from ripe apples by Sporidiobolus salmonicolor and Tilletiopsis washingtonensis. PubMed: Wavelength dependence of light-induced lipid oxidation and naturally occurring photosensitizers in cheese. PubMed: Changes in the volatile compounds and chemical and physical properties of Kuerle fragrant pear (Pyrus serotina Reld) during storage. PubMed: Synthesis and characterization of zinc AP-MOCVD precursors and their utility in the growth of ZnO. PubMed: Characterization of aroma compounds of chinese "Wuliangye" and "Jiannanchun" liquors by aroma extract dilution analysis. PubMed: Composition of volatiles of banana cultivars from Madeira Island. PubMed: Biosynthesis of straight-chain ester volatiles in red delicious and granny smith apples using deuterium-labeled precursors. PubMed: An improved method for 14C-labelling of farnesylacetic acid and its geranyl ester. PubMed: Attraction and antennal response of the common wasp, Vespula vulgaris (L.), to selected synthetic chemicals in New Zealand beech forests. PubMed: Strategies for enzymatic esterification in organic solvents: comparison of microaqueous, biphasic, and micellar systems. PubMed: Immobilization of Candida antarctica lipase B by adsorption to green coconut fiber. PubMed: Characterization of fermentative behaviors of lactic acid bacteria in grape wines through 1H NMR- and GC-based metabolic profiling. PubMed: The effect of ultrasonic pre-treatment on the catalytic activity of lipases in aqueous and non-aqueous media. PubMed: Covalent attachment of Candida rugosa lipase on chemically modified hybrid matrix of polysiloxane-polyvinyl alcohol with different activating compounds. PubMed: Characterization and utilization of Candida rugosa lipase immobilized on controlled pore silica. PubMed: Rice straw as a support for immobilization of microbial lipase. PubMed: Aromatic profile of aqueous banana essence and banana fruit by gas chromatography-mass spectrometry (GC-MS) and gas chromatography-olfactometry (GC-O). PubMed: Subsegmentation of the human liver. PubMed: A comparison of acylation, phosphorylation and binding in related substrates and inhibitors of serum cholinesterase. PubMed: Chemesthesis from volatile organic compounds: Psychophysical and neural responses. PubMed: Understanding structure-stability relationships of Candida antartica lipase B in ionic liquids. PubMed: Criteria to design green enzymatic processes in ionic liquid/supercritical carbon dioxide systems. PubMed: Heterologous expression of the Saccharomyces cerevisiae alcohol acetyltransferase genes in Clostridium acetobutylicum and Escherichia coli for the production of isoamyl acetate. PubMed: Continuous green biocatalytic processes using ionic liquids and supercritical carbon dioxide. PubMed: Esterification activity and stability of Candida rugosa lipase immobilized into chitosan. PubMed: Selection of stabilizing additive for lipase immobilization on controlled pore silica by factorial design. PubMed: Competitive lipase-catalyzed ester hydrolysis and ammoniolysis in organic solvents; equilibrium model of a solid-liquid-vapor system. PubMed: Modification of responses byCampylomma verbasci (Heteroptera: Miridae) to pheromone blends in atmospheres permeated with synthetic sex pheromone or individual components.