cyclododecane
Identification
| Name | cyclododecane |
| CAS Number | 294-62-2 |
| EINECS | 206-033-9 |
| FDA UNII | 97CN13ZD83 |
| Molecular Formula | C12 H24 |
| Molecular Weight | 168.32328000 |
| MDL Number | MFCD00014258 |
| Nikkaji Number | J43.296B |
| Beilstein | 1901008 |
| XlogP3 | 6.70 (est) |
Regulatory
Physical Properties
| Appearance | white waxy solid (est) |
| Assay | 99.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 60.00 to 61.00 °C. @ 760.00 mm Hg |
| Boiling Point | 247.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 10.000000 mmHg @ 100.00 °C. |
| Flash Point | 198.00 °F. TCC ( 92.22 °C. ) |
| logP (o/w) | 6.325 (est) |
| Soluble in | water, 0.1075 mg/L @ 25 °C (est) |
| Insoluble in | water |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | subcutaneous-mouse LD50 > 10000 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavoring agents |
| Recommendation for cyclododecane usage levels up to | not for fragrance use. |
Potential Uses
Natural Occurrence
Synonyms
cyclododecane
PubMed:
Secondary Organic Aerosol Composition from C12 Alkanes.
PubMed:
Self-assembly triggered by self-assembly: Optically active, paramagnetic micelles encapsulated in protein cage nanoparticles.
PubMed:
In vivo imaging of the glucagonlike peptide 1 receptor in the pancreas with 68Ga-labeled DO3A-exendin-4.
PubMed:
Methodology for labeling proteins and peptides with lead-212 (212Pb).
PubMed:
Paternally inherited ABCC8 mutation causing diffuse congenital hyperinsulinism.
PubMed:
Sensitization of tumor to ²¹²Pb radioimmunotherapy by gemcitabine involves initial abrogation of G2 arrest and blocked DNA damage repair by interference with Rad51.
PubMed:
The preferred conformation of erythro- and threo-1,2-difluorocyclododecanes.
PubMed:
Eryngiolide A, a cytotoxic macrocyclic diterpenoid with an unusual cyclododecane core skeleton produced by the edible mushroom Pleurotus eryngii.
PubMed:
Sublimable C5A delivery provides sustained and prolonged anti-HIV microbicidal activities.
PubMed:
Molecular recognition of hydrocarbon guests by a supramolecular capsule formed by the 4:4 self-assembly of tris(Zn(2+)-cyclen) and trithiocyanurate in aqueous solution.
PubMed:
(212)Pb-radioimmunotherapy induces G(2) cell-cycle arrest and delays DNA damage repair in tumor xenografts in a model for disseminated intraperitoneal disease.
PubMed:
Cyclododecane exposure in the field of conservation and restoration of art objects.
PubMed:
Screening of a minimal enriched P450 BM3 mutant library for hydroxylation of cyclic and acyclic alkanes.
PubMed:
Imaging human pancreatic cancer xenografts by targeting mutant KRAS2 mRNA with [(111)In]DOTA(n)-poly(diamidopropanoyl)(m)-KRAS2 PNA-D(Cys-Ser-Lys-Cys) nanoparticles.
PubMed:
Complexation of syndiotactic polystyrene with 12-crown-4.
PubMed:
Facile synthesis of 1-(acetic acid)-4,7,10-tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraaza-cyclododecane: a reactive precursor chelating agent.
PubMed:
A new bifunctional Gd(III) complex of enhanced efficacy for MR-molecular imaging applications.
PubMed:
Radiosynthesis of new [90Y]-DOTA-based maleimide reagents suitable for the prelabeling of thiol-bearing L-oligonucleotides and peptides.
PubMed:
Design of (Gd-DO3A)n-polydiamidopropanoyl-peptide nucleic acid-D(Cys-Ser-Lys-Cys) magnetic resonance contrast agents.
PubMed:
Stratigraphic analysis of organic materials in wall painting samples using micro-FTIR attenuated total reflectance and a novel sample preparation technique.
PubMed:
PET imaging of CCND1 mRNA in human MCF7 estrogen receptor positive breast cancer xenografts with oncogene-specific [64Cu]chelator-peptide nucleic acid-IGF1 analog radiohybridization probes.
PubMed:
Radiohybridization PET imaging of KRAS G12D mRNA expression in human pancreas cancer xenografts with [(64)Cu]DO3A-peptide nucleic acid-peptide nanoparticles.
PubMed:
One-pot synthesis of lactams from cycloalkanes and tert-butyl nitrite by using N-hydroxyphthalimide as key catalyst.
PubMed:
Transition-metal (Ti,V,Cr,Mn,Fe,Co,Cu) containing ordered nanoporous materials: novel heterogeneous catalysts for selective oxidation reactions.
PubMed:
An apparent critical point in binary mixtures: experimental and simulation study.
PubMed:
On the development of sensor molecules that display Fe(III)-amplified fluorescence.
PubMed:
Mass, EPR, IR and electronic spectroscopic studies on newly synthesized macrocyclic ligand and its transition metal complexes.
PubMed:
Preparation and preliminary biological evaluation of a 177Lu labeled sanazole derivative for possible use in targeting tumor hypoxia.
PubMed:
A comparison of the fish bioconcentration factors for brominated flame retardants with their nonbrominated analogues.
PubMed:
Synthesis and evaluation of novel bifunctional chelating agents based on 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid for radiolabeling proteins.
PubMed:
Formation of two diverse classes of poly(amino-alkoxide) chelates and their mononuclear and polynuclear lanthanide(III) complexes.
PubMed:
Synthesis and DNA binding properties of a cationic 2,2':6',2"-terpyridine cobalt(II) complex containing an oligopeptide.
PubMed:
Synthesis and notable antimalarial activity of acyclic peroxides, L-(alkyldioxy)-L-(methyldioxy)cyclododecanes.
PubMed:
Metal ion-dependent molecular inclusion chemistry: inclusion of aromatic anions by coordinated 1,4,7,10-tetrakis((S)-2-hydroxy-3-phenoxypropyl)-1,4,7,10-tetraazacyclododecane.
PubMed:
Conformational Study of trans-Cyclododecene by Dynamic NMR Spectroscopy and Computational Methods.
PubMed:
Intercalation of multiple carbon atoms between the carbonyls of alpha-diketones.
PubMed:
Oligonucleotide conjugates of Eu(III) tetraazamacrocycles with pendent alcohol and amide groups promote sequence-specific RNA cleavage.
PubMed:
Synthesis, characterization, and evaluation of a novel bifunctional chelating agent for the lead isotopes 203Pb and 212Pb.
PubMed:
Is absolute noninvasive temperature measurement by the Pr[MOE-DO3A] complex feasible.
PubMed:
Improved synthesis of the bifunctional chelating agent 1,4,7,10-tetraaza-N-(1-carboxy-3-(4-nitrophenyl)propyl)-N',N'',N'''-tri s(acetic acid)cyclododecane (PA-DOTA).
PubMed:
Fast spectroscopic imaging for non-invasive thermometry using the Pr[MOE-DO3A] complex.
PubMed:
Degradation of alicyclic molecules by Rhodococcus ruber CD4.
PubMed:
Metal ion-dependent hydrolysis of RNA phosphodiester bonds within hairpin loops. A comparative kinetic study on chimeric ribo/2'-O-methylribo oligonucleotides.
PubMed:
Conformational analysis of six- and twelve-membered ring compounds by molecular dynamics.
PubMed:
Conformational and Coordination Equilibria on DOTA Complexes of Lanthanide Metal Ions in Aqueous Solution Studied by (1)H-NMR Spectroscopy.
PubMed:
Phase I study of intravenous Lu-labeled CC49 murine monoclonal antibody in patients with advanced adenocarcinoma.
PubMed:
Effects of cyclic 12-, 8-, and 6-carbon compounds on glutathione S-transferase activity.
PubMed:
Ferric enterobactin transport system in Escherichia coli K-12. Extraction, assay, and specificity of the outer membrane receptor.
PubMed:
Structural effects on Arthrobacter methylene hydroxylase activity.
PubMed:
Some derivatives of cyclododecane.