Identification

Namecyclododecane
CAS Number294-62-2
EINECS206-033-9
FDA UNII97CN13ZD83
Molecular FormulaC12 H24
Molecular Weight168.32328000
MDL NumberMFCD00014258
Nikkaji NumberJ43.296B
Beilstein1901008
XlogP36.70 (est)

Regulatory

Physical Properties

Appearance white waxy solid (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 60.00 to 61.00 °C. @ 760.00 mm Hg
Boiling Point 247.00 °C. @ 760.00 mm Hg
Vapor Pressure 10.000000 mmHg @ 100.00 °C.
Flash Point 198.00 °F. TCC ( 92.22 °C. )
logP (o/w) 6.325 (est)
Soluble in water, 0.1075 mg/L @ 25 °C (est)
Insoluble in water

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal Toxicitysubcutaneous-mouse LD50 > 10000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavoring agents
Recommendation for cyclododecane usage levels up tonot for fragrance use.

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Potential Uses

None Found

Natural Occurrence

beef PMC chamomile garden chamomile plant passiflora galbana passiflora mucronata sesame seed roasted

Synonyms

cyclododecane PubMed: Secondary Organic Aerosol Composition from C12 Alkanes. PubMed: Self-assembly triggered by self-assembly: Optically active, paramagnetic micelles encapsulated in protein cage nanoparticles. PubMed: In vivo imaging of the glucagonlike peptide 1 receptor in the pancreas with 68Ga-labeled DO3A-exendin-4. PubMed: Methodology for labeling proteins and peptides with lead-212 (212Pb). PubMed: Paternally inherited ABCC8 mutation causing diffuse congenital hyperinsulinism. PubMed: Sensitization of tumor to ²¹²Pb radioimmunotherapy by gemcitabine involves initial abrogation of G2 arrest and blocked DNA damage repair by interference with Rad51. PubMed: The preferred conformation of erythro- and threo-1,2-difluorocyclododecanes. PubMed: Eryngiolide A, a cytotoxic macrocyclic diterpenoid with an unusual cyclododecane core skeleton produced by the edible mushroom Pleurotus eryngii. PubMed: Sublimable C5A delivery provides sustained and prolonged anti-HIV microbicidal activities. PubMed: Molecular recognition of hydrocarbon guests by a supramolecular capsule formed by the 4:4 self-assembly of tris(Zn(2+)-cyclen) and trithiocyanurate in aqueous solution. PubMed: (212)Pb-radioimmunotherapy induces G(2) cell-cycle arrest and delays DNA damage repair in tumor xenografts in a model for disseminated intraperitoneal disease. PubMed: Cyclododecane exposure in the field of conservation and restoration of art objects. PubMed: Screening of a minimal enriched P450 BM3 mutant library for hydroxylation of cyclic and acyclic alkanes. PubMed: Imaging human pancreatic cancer xenografts by targeting mutant KRAS2 mRNA with [(111)In]DOTA(n)-poly(diamidopropanoyl)(m)-KRAS2 PNA-D(Cys-Ser-Lys-Cys) nanoparticles. PubMed: Complexation of syndiotactic polystyrene with 12-crown-4. PubMed: Facile synthesis of 1-(acetic acid)-4,7,10-tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraaza-cyclododecane: a reactive precursor chelating agent. PubMed: A new bifunctional Gd(III) complex of enhanced efficacy for MR-molecular imaging applications. PubMed: Radiosynthesis of new [90Y]-DOTA-based maleimide reagents suitable for the prelabeling of thiol-bearing L-oligonucleotides and peptides. PubMed: Design of (Gd-DO3A)n-polydiamidopropanoyl-peptide nucleic acid-D(Cys-Ser-Lys-Cys) magnetic resonance contrast agents. PubMed: Stratigraphic analysis of organic materials in wall painting samples using micro-FTIR attenuated total reflectance and a novel sample preparation technique. PubMed: PET imaging of CCND1 mRNA in human MCF7 estrogen receptor positive breast cancer xenografts with oncogene-specific [64Cu]chelator-peptide nucleic acid-IGF1 analog radiohybridization probes. PubMed: Radiohybridization PET imaging of KRAS G12D mRNA expression in human pancreas cancer xenografts with [(64)Cu]DO3A-peptide nucleic acid-peptide nanoparticles. PubMed: One-pot synthesis of lactams from cycloalkanes and tert-butyl nitrite by using N-hydroxyphthalimide as key catalyst. PubMed: Transition-metal (Ti,V,Cr,Mn,Fe,Co,Cu) containing ordered nanoporous materials: novel heterogeneous catalysts for selective oxidation reactions. PubMed: An apparent critical point in binary mixtures: experimental and simulation study. PubMed: On the development of sensor molecules that display Fe(III)-amplified fluorescence. PubMed: Mass, EPR, IR and electronic spectroscopic studies on newly synthesized macrocyclic ligand and its transition metal complexes. PubMed: Preparation and preliminary biological evaluation of a 177Lu labeled sanazole derivative for possible use in targeting tumor hypoxia. PubMed: A comparison of the fish bioconcentration factors for brominated flame retardants with their nonbrominated analogues. PubMed: Synthesis and evaluation of novel bifunctional chelating agents based on 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid for radiolabeling proteins. PubMed: Formation of two diverse classes of poly(amino-alkoxide) chelates and their mononuclear and polynuclear lanthanide(III) complexes. PubMed: Synthesis and DNA binding properties of a cationic 2,2':6',2"-terpyridine cobalt(II) complex containing an oligopeptide. PubMed: Synthesis and notable antimalarial activity of acyclic peroxides, L-(alkyldioxy)-L-(methyldioxy)cyclododecanes. PubMed: Metal ion-dependent molecular inclusion chemistry: inclusion of aromatic anions by coordinated 1,4,7,10-tetrakis((S)-2-hydroxy-3-phenoxypropyl)-1,4,7,10-tetraazacyclododecane. PubMed: Conformational Study of trans-Cyclododecene by Dynamic NMR Spectroscopy and Computational Methods. PubMed: Intercalation of multiple carbon atoms between the carbonyls of alpha-diketones. PubMed: Oligonucleotide conjugates of Eu(III) tetraazamacrocycles with pendent alcohol and amide groups promote sequence-specific RNA cleavage. PubMed: Synthesis, characterization, and evaluation of a novel bifunctional chelating agent for the lead isotopes 203Pb and 212Pb. PubMed: Is absolute noninvasive temperature measurement by the Pr[MOE-DO3A] complex feasible. PubMed: Improved synthesis of the bifunctional chelating agent 1,4,7,10-tetraaza-N-(1-carboxy-3-(4-nitrophenyl)propyl)-N',N'',N'''-tri s(acetic acid)cyclododecane (PA-DOTA). PubMed: Fast spectroscopic imaging for non-invasive thermometry using the Pr[MOE-DO3A] complex. PubMed: Degradation of alicyclic molecules by Rhodococcus ruber CD4. PubMed: Metal ion-dependent hydrolysis of RNA phosphodiester bonds within hairpin loops. A comparative kinetic study on chimeric ribo/2'-O-methylribo oligonucleotides. PubMed: Conformational analysis of six- and twelve-membered ring compounds by molecular dynamics. PubMed: Conformational and Coordination Equilibria on DOTA Complexes of Lanthanide Metal Ions in Aqueous Solution Studied by (1)H-NMR Spectroscopy. PubMed: Phase I study of intravenous Lu-labeled CC49 murine monoclonal antibody in patients with advanced adenocarcinoma. PubMed: Effects of cyclic 12-, 8-, and 6-carbon compounds on glutathione S-transferase activity. PubMed: Ferric enterobactin transport system in Escherichia coli K-12. Extraction, assay, and specificity of the outer membrane receptor. PubMed: Structural effects on Arthrobacter methylene hydroxylase activity. PubMed: Some derivatives of cyclododecane.