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Synonyms
didronel R
disodium (1-hydroxyethylidene)diphosphonate
disodium 1-hydroxyethylidene phosphonate
disodium dihydrogen (1-hydroxyethylidene) bisphosphonate
disodium dihydrogen (1-hydroxyethylidene)bisphosphonate
disodium dihydrogen (1-hydroxyethylidene)diphosphonate
disodium ethane-1-hydroxy-1,1-diphosphonate
disodium ethanol-1,1-diphosphonate
disodium ethydronate
disodium;hydroxy-[1-hydroxy-1-[hydroxy(oxido)phosphoryl]ethyl]phosphinate
ethane-1-hydroxy-1,1-diphosphonate, disodium salt
ethane-1-hydroxy-1,1-diphosphonic acid, disodium salt
etidronate disodium
(1-
hydroxyethane-1,1-diyl)diphosphonic acid disodium salt
1-
hydroxyethylidene-1,1-diphosphonic acid disodium salt
(1-
hydroxyethylidene)diphosphonic acid, disodium salt
phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt
phosphonic acid, (1-hydroxyethylidene)di-, disodium salt
phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:2)
PubMed:
Prediction of bioavailability of selected bisphosphonates using in silico methods towards categorization into a biopharmaceutical classification system.
PubMed:
[Establishment of zebrafish osteopenia model induced by dexamethasone].
PubMed:
Efficacy and safety of 2-year etidronate treatment in a child with generalized arterial calcification of infancy.
PubMed:
Bedside ultrasound in early diagnosis of neurogenic heterotopic ossification in patients with acquired brain injury.
PubMed:
WITHDRAWN: Pharmacological interventions for treating acute heterotopic ossification.
PubMed:
Long-term results of disodium etidronate treatment in pulmonary alveolar microlithiasis.
PubMed:
Oroantral fistula from bisphosphonate induced osteonecrosis of the jaw.
PubMed:
Intracanal bisphosphonate does not inhibit replacement resorption associated with delayed replantation of monkey incisors.
PubMed:
Disturbance of inorganic phosphate metabolism in diabetes mellitus: temporary therapeutic intervention trials.
PubMed:
Application of UV-derivative spectrophotometry for determination of some bisphosphonates drugs in pharmaceutical formulations.
PubMed:
Etidronate: what is its place in treatment of primary osteoporosis and other demineralizing diseases today?
PubMed:
Direct stability-indicating method development and validation for analysis of etidronate disodium using a mixed-mode column and charged aerosol detector.
PubMed:
Longterm effect of intermittent cyclical etidronate therapy on corticosteroid-induced osteoporosis in Japanese patients with connective tissue disease: 7-year followup.
PubMed:
Intractable wounds caused by calcific uremic arteriolopathy treated with bisphosphonates.
PubMed:
The use of eidronate disodium in the prevention of heterotopic ossification in burn patients.
PubMed:
Historical perspectives on the clinical development of bisphosphonates in the treatment of bone diseases.
PubMed:
Successful treatment of a patient with severe calcific uremic arteriolopathy (calciphylaxis) by etidronate disodium.
PubMed:
Pseudogout attack induced during etidronate disodium therapy.
PubMed:
Brain calcifications induce neurological dysfunction that can be reversed by a bone drug.
PubMed:
Ossification of the Achilles tendon--a case report.
PubMed:
Calcinosis universalis: a rare diagnosis.
PubMed:
[Heterotopic ossification in spinal cord injured patients].
PubMed:
Effect of administration of retinol and etidronate on bone histomorphometric parameters in ovariectomized rats.
PubMed:
Recurrent vesical calculi, hypercalciuria, and biochemical evidence of increased bone resorption in an adult male with paraplegia due to spinal cord injury: is there a role for intermittent oral disodium etidronate therapy for prevention of calcium phosphate bladder stones?
PubMed:
Pharmacological interventions for treating acute heterotopic ossification.
PubMed:
Effect of intermittent cyclical etidronate therapy on corticosteroid induced osteoporosis in Japanese patients with connective tissue disease: 3 year followup.
PubMed:
Spectrophotometric determination of some drugs for osteoporosis.
PubMed:
Chinese herbs and bone disease.
PubMed:
Pulmonary alveolar microlithiasis in childhood: clinical and radiological follow-up.
PubMed:
Idiopathic calciphylaxis.
PubMed:
Conventional treatment of hypercalcemia of malignancy.
PubMed:
Advances in the biology and treatment of myeloma bone disease.
PubMed:
Familial fibrodysplasia ossificans progressiva: trial with etidronate disodium.
PubMed:
Paget's disease of the spine and its management.
PubMed:
Etidronic acid and steroid therapy: new indication. No proven impact on fractures.
PubMed:
Effect of intermittent cyclical treatment with etidronate disodium (HEBP) and calcium plus alphacalcidol in postmenopausal osteoporosis.
PubMed:
Prevalence and determinants of osteoporosis drug prescription among patients with high exposure to glucocorticoid drugs.
PubMed:
Risedronate: a clinical review.
PubMed:
Complexometric determination of diphosphonic acid derivatives. Part II.
PubMed:
Etidronate inhibits human osteoblast apoptosis by inhibition of pro-apoptotic factor(s) produced by activated T cells.
PubMed:
Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget's disease.
PubMed:
Etridronate therapy in the treatment and prevention of osteoporosis.
PubMed:
Acute alteration in bone mineral density and biochemical markers for bone metabolism in nephrotic patients receiving high-dose glucocorticoid and one-cycle etidronate therapy.
PubMed:
36 month intermittent cyclical etidronate treatment in patients with established corticosteroid induced osteoporosis.
PubMed:
A patient with Paget's disease of bone treated with etidronate disodium.
PubMed:
Effects of etidronate disodium on crystallizations in synthetic urine and calcium oxalate crystal adhesion to Madin-Darby canine kidney (MDCK) cells.
PubMed:
Functional improvement in a patient with cerebral calcinosis using a bisphosphonate.
PubMed:
The use of cyclical etidronate in osteoporosis: changes after completion of 3 years treatment.
PubMed:
A comparative study on biochemical markers of bone collagen breakdown in post-menopausal women.
PubMed:
Massive osteolytic bone metastases from a primary aortic sarcoma: a case report.
PubMed:
Myositis ossificans complicating severe Guillain-Barré syndrome.
PubMed:
Effect of intermittent cyclical disodium etidronate therapy on bone mineral density in men with vertebral fractures.
PubMed:
Analysis of selected diphosphonic acid derivatives used in treatment of osteoporosis. Part I. Complexometric determination of diphosphonic acid derivatives.
PubMed:
Bisphosphonates for controlling pain from metastatic bone disease.
PubMed:
Prevention of bone loss in cardiac transplant recipients. A comparison of biphosphonates and vitamin D.
PubMed:
[Pseudosarcomatous osteolysis of the femur in a patient with Paget's bone disease treated with long-term etidronate disodium: apropos of a new case].
PubMed:
New biochemical markers of bone resorption derived from collagen breakdown in the study of postmenopausal osteoporosis.
PubMed:
Critical drug appraisal: etidronate intermittent cyclic therapy for postmenopausal osteoporosis.
PubMed:
Clinical effect of etidronate disodium (EHDP) on heterotopic ossification following total hip arthroplasty.
PubMed:
Direct stereological estimation of three-dimensional connectivity in rat vertebrae: effect of estrogen, etidronate and risedronate following ovariectomy.
PubMed:
Myositis ossificans progressiva: a 10-year follow-up on a patient treated with etidronate disodium.
PubMed:
Etretinate-induced heterotopic bone formation about the hip joint. A case report including ultrastructural study.
PubMed:
Comparison of changes in bone mineral in idiopathic and secondary osteoporosis following therapy with cyclical disodium etidronate and high dose calcium supplementation.
PubMed:
Determination of bisphosphonate drugs in pharmaceutical dosage formulations by ion chromatography with indirect UV detection.
PubMed:
An experience of ischemic limb salvage associated with myositis ossificans of the left thigh.
PubMed:
Evaluation of a 24-hour infusion of etidronate disodium for the treatment of hypercalcemia of malignancy.
PubMed:
Hereditary hyperphosphatasia: 20 year follow-up and response to disodium etidronate.
PubMed:
Bone histomorphometric changes after cyclic therapy with phosphate and etidronate disodium in women with postmenopausal osteoporosis.
PubMed:
Antiresorptive drugs and trabecular bone turnover: validation and testing of a computer model.
PubMed:
Rachitic syndrome after disodium etidronate therapy in an adolescent.
PubMed:
Etidronate inhibits the thyroid hormone-induced bone loss in rats assessed by bone mineral density and messenger ribonucleic acid markers of osteoblast and osteoclast function.
PubMed:
Intravenous disodium etidronate therapy in spinal cord injury patients with heterotopic ossification.
PubMed:
Persistent hypercoagulation associated with heterotopic ossification in patients with spinal cord injury long after injury has occurred.
PubMed:
The effects of etidronate disodium on progressive hearing loss from otosclerosis.
PubMed:
Indomethacin and disodium etidronate for the prevention of recurrence of heterotopic ossification after surgical resection. Two case reports.
PubMed:
Giant cell tumor arising in Paget's disease of bone. Recurrences after 36 years.
PubMed:
[Indications and limitations of non-hormonal treatments of osteoporosis].
PubMed:
Determination of etidronate disodium tablets by ion chromatography with indirect UV detection.
PubMed:
[A one-year prospective study of disodium etidronate versus 17 beta estradiol in the prevention of postmenopausal osteoporosis].
PubMed:
[A rare cause of hypercalcemia: familial hypocalciuric hypercalcemia].
PubMed:
Protective effects of disodium etidronate and pamidronate against the biomechanical repercussion of betamethasone-induced osteopenia in growing rat femurs.
PubMed:
Didronel PMO.
PubMed:
[Osteoma cutis. Pathogenesis and therapeutic possibilities].
PubMed:
Retention of etidronate in human, dog, and rat.
PubMed:
Skeletal nonvisualization in a bone scan secondary to intravenous etidronate therapy.
PubMed:
Warfarin in prevention of heterotopic ossification.
PubMed:
Spontaneous fractures in a patient treated with low doses of etidronic acid (disodium etidronate).
PubMed:
Heterotopic bone formation in abdominal incisions.
PubMed:
Gallium nitrate.
PubMed:
Comparative study of pamidronate disodium and etidronate disodium in the treatment of cancer-related hypercalcemia.
PubMed:
Treatment of pulmonary alveolar microlithiasis with a diphosphonate--preliminary results of a case.
PubMed:
Calcinosis and metastatic calcification due to vitamin D intoxication. A case report and review.
PubMed:
Therapies for symptomatic primary osteoporosis.
PubMed:
Duration of etidronate effect demonstrated by serial bone scintigraphy.
PubMed:
Effect of daily etidronate on the osteolysis of multiple myeloma.
PubMed:
Pharmacologic elevation of blood inorganic phosphate in hypoxemic patients with COPD.
PubMed:
Etidronate for hypercalcemia of malignancy and osteoporosis.
PubMed:
Heterotopic ossification and peripheral nerve entrapment: early diagnosis and excision.
PubMed:
Estrogen and diphosphonate treatment provide long-term protection against osteopenia in ovariectomized rats.
PubMed:
Treatment of hypercalcemia of malignancy with intravenous etidronate. A controlled, multicenter study. The Hypercalcemia Study Group.
PubMed:
Effect of etidronate disodium on the development of bone lesions in an animal model of bone metastasis using the human prostate cancer cell line PC-3.
PubMed:
Effectiveness of a 24-hour infusion of etidronate disodium in the treatment of hypercalcemia of malignant disease. A dose-ranging pilot study.
PubMed:
Advances in the management of Paget's disease of bone.
PubMed:
Idiopathic infantile arterial calcification in two siblings: failure of treatment with diphosphonate.
PubMed:
Pseudoarthrosis in heterotopic ossification in spinal cord-injured patients.
PubMed:
[A new case of pseudosarcomatous osteolysis in a patient with Paget's disease treated with disodium etidronate].
PubMed:
Endocrine and pharmacological suppressors of bone turnover protect against osteopenia in ovariectomized rats.
PubMed:
Pharmacologic management of Paget's disease.
PubMed:
Clinical and radiographic improvement of bone of the second lumbar vertebra in Paget's disease following therapy with etidronate disodium: a case report.
PubMed:
Vitamin D in Paget's disease of bone.
PubMed:
[Paget's disease: errors to be avoided].
PubMed:
[Fibrodysplasia ossificans progressiva or Münchmeyer's disease].
PubMed:
Cyclic therapy of osteoporosis with neutral phosphate and brief, high-dose pulses of etidronate.
PubMed:
[Long-term follow-up of 88 patients with Paget's disease treated by discontinuous courses of low-dose disodium etidronate].
PubMed:
Effect of etidronate disodium on bone turnover following surgical menopause.
PubMed:
Treatment of painful prostatic bone metastases with oral etidronate disodium.
PubMed:
Establishment of a model to evaluate inhibition of bone resorption induced by human prostate cancer cells in nude mice.
PubMed:
Stabilization of hearing loss in Paget's disease with calcitonin and etidronate.
PubMed:
False-negative bone imaging due to etidronate disodium therapy.
PubMed:
A clinical and biochemical assessment of etidronate disodium in patients with active rheumatoid arthritis.
PubMed:
[Effects of etidronate disodium (EHDP) on urogenital malignancies with bone metastasis: a multicentered collaborative evaluation].
PubMed:
[Failure of cimetidine and etidronate disodium to suppress parathyroid hormone level and hypercalcemia in primary hyperparathyroidism].
PubMed:
Medical treatment of primary hyperparathyroidism: effects on parathormone and vitamin D metabolites.
PubMed:
Influence of disodium etidronate on Paget's disease of bone.
PubMed:
Synthetic human calcitonin in refractory Paget's disease of bone.
PubMed:
Heterotopic ossification and pseudoarthrosis in the shoulder following encephalitis. A case report and review of the literature.
PubMed:
Low back pain in Paget's disease of bone.
PubMed:
Therapy of hypercalcemia of malignancy.
PubMed:
Intravenous disodium etidronate therapy in Paget's disease of bone and hypercalcemia of malignancy. Effects on biochemical parameters and bone histomorphometry.
PubMed:
Effects of intravenous etidronate disodium on skeletal and calcium metabolism.
PubMed:
Etidronate disodium in the management of malignancy-related hypercalcemia.
PubMed:
Effect of etidronate disodium on the interactions between malignancy and bone.
PubMed:
Etidronate disodium: a new therapy for hypercalcemia of malignancy. Proceedings of a symposium.
PubMed:
Neoplastic hypercalcemia: physiologic response to intravenous etidronate disodium.
PubMed:
The effect of 1 alpha-hydroxyvitamin D3 on the mineralization defect in disodium etidronate-treated Paget's disease--a double-blind randomized clinical study.
PubMed:
Effect of disodium etidronate (EHDP) on bone ingrowth in a porous material.
PubMed:
Biochemical response to combination of disodium etidronate with calcitonin in Paget's disease.
PubMed:
A model of localized osteolysis induced by the MBT-2 tumor in mice and its responsiveness to etidronate disodium.
PubMed:
Efficacy of oral administration of etidronate disodium in maintaining normal serum calcium levels in previously hypercalcemic cancer patients.
PubMed:
Resection of heterotopic ossification and Didronel therapy--regaining wheelchair independence in the spinal cord injured patient.
PubMed:
Relief of metastatic bone pain with etidronate disodium.
PubMed:
Etidronate disodium for treating hypercalcaemia of malignancy: a double blind, placebo-controlled study.
PubMed:
Accelerated bone formation causing profound hypocalcemia in acute leukemia.
PubMed:
Immobilization hypercalcemia associated with Landry-Guillain-Barré syndrome. Successful therapy with combined calcitonin and etidronate.
PubMed:
[Congenital osteoma of the skin. Attempt at diphosphonate therapy].
PubMed:
Spontaneous fractures of uninvolved bones in patients with Paget's disease during unduly prolonged treatment with disodium etidronate (EHDP).
PubMed:
A dynamic classification of Paget's disease.
PubMed:
Effective short term treatment of Paget's disease with oral etidronate.
PubMed:
Long-term follow-up of therapy with intermittent etidronate disodium in Paget's disease of bone.
PubMed:
Advances in the treatment of metastatic prostatic cancer.
PubMed:
Paget's disease of bone. An update on management.
PubMed:
Progressive ossifying myositis in a cat.
PubMed:
Dose-dependent absorption of disodium etidronate.
PubMed:
Dose-dependent effect of calcium and magnesium etidronate on salicylic acid absorption in the rat.
PubMed:
[Evolution of Paget's disease of bone during and after treatment with small doses of disodium etidronate (EHDP)].
PubMed:
[Effect of etidronate disodium (EHDP) on calcium oxalate renal stones induced by synthetic 1 alpha(OH) vitamin D3 and ethylene glycol in rats].
PubMed:
[EHDP (ethylidene-1-hydroxy-1,1-diphosphonate) in the treatment of polyosseous Paget disease].
PubMed:
Comparative study of etidronate and SR 41319, a new diphosphonate, on passive cutaneous anaphylaxis and phospholipase A2 activity.
PubMed:
[Treatment of Paget's disease with low dose sodium etidronate (5mg/kg/day). Occurrence of reversible transient suspected leukopenia].
PubMed:
Calcinosis universalis treated with disodium etidronate.
PubMed:
Intravenous etidronate in the management of malignant hypercalcemia.
PubMed:
Treatment of cancer-associated hypercalcemia with mithramycin and oral etidronate disodium.
PubMed:
Reduction of skeletal blood flow in Paget's disease with disodium etidronate therapy.
PubMed:
[Studies of the kinetics of bone concentration of mdp-tc 99m in Paget's disease and various treatment methods].
PubMed:
[Progressive myositis ossificans. Report of a case and results of treatment with disodium etidronate].
PubMed:
Acute intravenous infusion of disodium dihydrogen (1-hydroxyethylidene)diphosphonate: mechanism of toxicity.
PubMed:
Effect of decreased O2 affinity of hemoglobin on work performance during exercise in healthy humans.
PubMed:
[Osteolysis, then fracture of the femur in a Paget's disease patient treated with high-dose disodium etidronate].
PubMed:
Immobilization hypercalcemia in acute spinal cord injury treated with etidronate.
PubMed:
Effects of disodium etidronate in murine tumor models.
PubMed:
Alternate calcitonin and etidronate disodium therapy for Paget's bone disease.
PubMed:
Focal osteomalacia due to low-dose diphosphonate therapy in Paget's disease.
PubMed:
Disodium etidronate in hypercalcaemia due to immobilisation.
PubMed:
Disodium etidronate (EHDP)
PubMed:
[Pseudosarcomatous osteolysis in a Paget's disease patient treated with disodium etidronate (EHDP)].
PubMed:
[Etidronic acid therapy in Paget's disease of bone].
PubMed:
Heterotopic ossification heralded by a knee effusion.
PubMed:
Disodium etidronate: its role in preventing heterotopic ossification in severe head injury.
PubMed:
Diphosphonate treatment for heterotopic ossification in spinal cord injury patients.
PubMed:
Treatment of hyperparathyroidism with etidronate disodium.
PubMed:
Diphosphonates and painful feet.
PubMed:
Review of fracture experience during treatment of Paget's disease of bone with etidronate disodium (EHDP).
PubMed:
Scalp vein sign in Paget's disease of bone.
PubMed:
Focal mineralization defect during disodium etidronate treatment of calcinosis.
PubMed:
Etidronate disodium in the treatment of Paget's disease of bone.
PubMed:
The effect of etidronate disodium (EHDP) on retinopathy in insulin-dependent diabetic patients.
PubMed:
[Treatment of Paget's disease with the combined administration of calcitonin and disodium etidronate].
PubMed:
Parenteral diphosphonates for treating malignant hypercalcemia.
PubMed:
Three adult cases resembling hereditary bone dysplasia.
PubMed:
Heterotopic ossification following hip replacement or spinal cord injury. Two clinical studies with EHDP.
PubMed:
[Treatment of hypercalcemia of tumoral origin with two diphosphonates].
PubMed:
Treatment of hypercalcemia with etidronate disodium.
PubMed:
Effect of etidronate disodium on filterability of sickle cell erythrocytes.
PubMed:
Fibrodysplasia ossificans progressiva. A survey of forty-two cases.
PubMed:
Fibrodysplasia ossificans progressiva (myositis ossificans progressiva) treatment with disodium etidronate.
PubMed:
Paget's disease and the nervous system.
PubMed:
Etidronate disodium for Paget's disease.
PubMed:
Fibrodysplasia ossificans progressiva. Biochemical changes in blood serum, urine, skin, bone, and ectopic ossification.
PubMed:
Fibrodysplasia (myositis) ossificans progressiva treated with disodium etidronate.
PubMed:
Use and complications of high-dose disodium etidronate therapy in fibrodysplasia ossificans progressiva.
PubMed:
Appearance of a gastric ulcer during diphosphonate therapy in a woman with CRST syndrome.
PubMed:
Urinary excretion of hydroxylysine and its glycosides as an index of collagen degradation.
PubMed:
[Treatment of 10 cases of symptomatic Paget's disease with etidronate (EHDP)].
PubMed:
Etidronate disodium in postmenopausal osteoporosis.
PubMed:
In vitro stabilization of a low-tin bone-imaging agent (99mTc-Sn-HEDP) by ascorbic acid.
PubMed:
Disodium etidronate in the prevention of heterotopic ossification following spinal cord injury (preliminary report).
PubMed:
Effects of a diphosphonate (disodium etidronate: EHDP) on phosphate metabolism in Paget's disease of bone, primary hyperparathyroidism and type I hypophosphataemic rickets.
PubMed:
Disodium etidronate in the prevention of postoperative recurrence of heterotopic ossification in spinal-cord injury patients.
PubMed:
Radioimmunoassay of procollagen in serum of patients with Paget's disease of bone.
PubMed:
Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment.
PubMed:
[Influence of disodium etidronate (EHDP) on plasma and urinary levels of sodium and potassium in humans].
PubMed:
Changes in the renal and extrarenal handling of phosphate induced by disodium etidronate (EHDP) in man.
PubMed:
Disodium etidronate therapy for dystrophic cutaneous calcification.
PubMed:
[Study of the therapeutic effects of disodium etidronate (EHDP) on hypercholesteremia and on hypertriglyceridemia].
PubMed:
Failure of disodium etidronate in calcinosis due to dermatomyositis and scleroderma.
PubMed:
[Diphosphonate (disodium etidronate) lowers cholesterol and total lipid levels in the blood of humans].
PubMed:
Influence of disodium etidronate on clinical and laboratory manifestations of Paget's disease of bone (osteitis deformans).
PubMed:
Paget's disease of bone. Experience with a diphosphonate (disodium etidronate) in treatment.
PubMed:
Intestinal absorption of disodium ethane-1-hydroxy-1,1-diphosphonate (disodium etidronate) using a deconvolution technique.
PubMed:
Preliminary safety assessment of disodium etidronate as an additive to experimental oral hygiene products.
PubMed:
Metabolism of disodium ethane-1-hydroxy-1,1-diphosphonate (disodium etidronate) in the rat, rabbit, dog and monkey.
PubMed:
The effects of disodium etidronate on the reproductive functions and embryogeny of albino rats and New Zealand rabbits.