sodium butyl paraben
sodium butyl 4-hydroxybenzoate
Identification
| Name | sodium butyl paraben |
| CAS Number | 36457-20-2 |
| EINECS | 253-049-7 |
| FDA UNII | MAR76J77VS |
| Molecular Formula | C11 H13 Na O3 |
| Molecular Weight | 216.21197928 |
| Nikkaji Number | J181.455I |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 309.20 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000356 mmHg @ 25.00 °C. (est) |
| Flash Point | 265.00 °F. TCC ( 129.20 °C. ) (est) |
| logP (o/w) | 3.459 (est) |
| Soluble in | water, 159 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | preservatives |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 230 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | preservatives |
| Recommendation for sodium butyl paraben usage levels up to | not for fragrance use. |
| Recommendation for sodium butyl paraben flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
benzoic acid, 4-hydroxy-, butyl ester, sodium salt (1:1)
benzoic acid, p-hydroxy-, butyl ester, sodium salt
butyl p-hydroxybenzoate sodium
butylparaben sodium salt
sodium 4-(butoxycarbonyl)phenolate
sodium butyl 4-hydroxybenzoate
sodium butyl hydroxybenozate
sodium butylparaben
sodium;4-butoxycarbonylphenolate
PubMed:
Fast and sensitive method to determine parabens by capillary electrophoresis using automatic reverse electrode polarity stacking mode: application to hair samples.
PubMed:
The photosensitized oxidation of mixture of parabens in aqueous solution.
PubMed:
Development studies on determination of preservatives decomposition products.
PubMed:
Biochemical characterization of Aspergillus oryzae native tannase and the recombinant enzyme expressed in Pichia pastoris.
PubMed:
Determination of parabens in beverage samples by dispersive liquid-liquid microextraction based on solidification of floating organic droplet.
PubMed:
Solid lipid nanoparticles as effective reservoir systems for long-term preservation of multidose formulations.
PubMed:
Simultaneous determination of eleven preservatives in cosmetics by micellar electrokinetic chromatography.
PubMed:
Dissociation constants of parabens and limiting conductances of their ions in water.
PubMed:
Simultaneous determination of electroactive and non-electroactive food preservatives by novel capillary electrophoresis with amperometric detection.
PubMed:
Simultaneous determination of p-hydroxybenzoic acid and parabens by capillary electrophoresis with improved sensitivity in nonaqueous media.
PubMed:
On-line pretreatment and determination of parabens in cosmetic products by combination of flow injection analysis, solid-phase extraction and micellar electrokinetic chromatography.
PubMed:
Optimisation of the caco-2 permeability assay using experimental design methodology.
PubMed:
Investigating protein haptenation mechanisms of skin sensitisers using human serum albumin as a model protein.
PubMed:
Optimisation of a solid-phase microextraction method for the determination of parabens in water samples at the low ng per litre level.
PubMed:
Separation of preservatives in cosmetic products by micellar electrokinetic chromatography.
PubMed:
Optimization by experimental design and artificial neural networks of the ion-interaction reversed-phase liquid chromatographic separation of twenty cosmetic preservatives.
PubMed:
Oxidation of p-hydroxybenzoic acid by Fenton's reagent.
PubMed:
Separation and determination of haloperidol, parabens and some of their degradation products by micellar electrokinetic chromatography.
PubMed:
Na(+)-translocating cytochrome bo terminal oxidase from Vitreoscilla: some parameters of its Na+ pumping and orientation in synthetic vesicles.
PubMed:
Paraben-associated autoanti-Jka antibodies. Three examples detected using commercially prepared low-ionic strength saline containing parabens.
PubMed:
On the solubilization properties of surfactant-polymer complexes.