acesulfame potassium

potassium salt of 3,4-dihydro-6-methyl-1,2,3-oxathiazine-4-one-2,2-dioxide

CAS: 55589-62-3 C4 H4 K N O4 S MW: 201.24298000 odorless sweet

Identification

Nameacesulfame potassium
CAS Number55589-62-3
EINECS259-715-3
FDA UNII23OV73Q5G9
Molecular FormulaC4 H4 K N O4 S
Molecular Weight201.24298000
MDL NumberMFCD00043833
Nikkaji NumberJ269.091H

Regulatory

JECFA Food AdditiveAcesulfame Potassium
GSFA CodexAcesulfame potassium (950)
DG SANTE Food Additivesacesulfame K
FDA Mainterm (SATF)55589-62-3 ; ACESULFAME POTASSIUM
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance white crystalline powder (exp)
Assay 95.00 to 100.00
Heavey Metals < 1 mg/kg Pb
Halogens < 3 mg/kg F
Food Chemicals Codex Listed No
Boiling Point 332.00 to 334.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.000001 mmHg @ 25.00 °C. (est)
Flash Point 311.00 °F. TCC ( 155.00 °C. )
logP (o/w) -0.310 (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)
Insoluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesfragrance

Organoleptic Properties

Odor Strength none
Odor Description at 100.00 %.
Taste Description sweet sugar candy

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorysweeteners, flavor enhancers
Recommendation for acesulfame potassium usage levels up tonot for fragrance use.

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Potential Uses

masking agents oral care agents sweetener

Natural Occurrence

not found in nature

Synonyms

ace K acesulfame K acesulfame potassium 6- methyl-1,2,3-oxathiazin-4 -one2,2-dioxidepotassiumsalt 6- methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide potassium salt 6- methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide, potassium salt 6- methyl-1,2,3-oxathiazin-4(3H)-one2,2-dioxidepotassiumsalt 6- methyl-3H-1,2,3-oxathiazine-2,2,4-trione, potassium salt 1,2,3- oxathiazin-4-ol, 6-methyl-, 2,2-dioxide, potassium salt (1:1) 1,2,3- oxathiazin-4(3H)-one, 6-methyl-, 2,2-dioxide, potassium salt potassium 6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide potassium 6-methyl-2,2-dioxooxathiazin-4-olate potassium 6-methyl-4-oxo-4H-1,2,3-oxathiazin-3-ide 2,2-dioxide potassium acesulfame potassium salt of 3,4-dihydro-6-methyl-1,2,3-oxathiazine-4-one-2,2-dioxide potassium salt of 6-methyl-1,2,3-oxathiazine-4(3H)-one-2,2-dioxide PubMed: Spatial characteristics of professional tennis serves with implications for serving aces: A machine learning approach. PubMed: Low-calorie sweetener use and energy balance: Results from experimental studies in animals, and large-scale prospective studies in humans. PubMed: [Development of a New Method for Determination of Sodium Saccharin and Acesulfame Potassium with the Aid of Coagulant]. PubMed: Nonnutritive Sweeteners in Breast Milk. PubMed: [Association between non-nutritive sweeteners and obesity risk among university students in Latin America]. PubMed: Simultaneous determination of sweeteners in beverages by LC-MS/MS. PubMed: [Consumption of carbonated beverages with nonnutritive sweeteners in Latin American university students]. PubMed: Acesulfame-K and pharmaceuticals as co-tracers of municipal wastewater in a receiving river. PubMed: Quantification of acesulfame potassium in processed foods by quantitative 1H NMR. PubMed: Allergic reaction caused by acesulfame potassium in foods. PubMed: [Modification of fasting blood glucose in adults with diabetes mellitus type 2 after regular soda and diet soda intake in the State of Querétaro, Mexico]. PubMed: Precise measurement for the purity of amino acid and peptide using quantitative nuclear magnetic resonance. PubMed: Sweet Taste-Sensing Receptors Expressed in Pancreatic β-Cells: Sweet Molecules Act as Biased Agonists. PubMed: Effects of three intense sweeteners on fat storage in the C. elegans model. PubMed: [A rapid dialysis method for analysis of artificial sweeteners in food]. PubMed: [Comprehensive evaluation of palatability for commercial medicine by taste sensing system]. PubMed: A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. PubMed: Ingestion of bacterial lipopolysaccharide inhibits peripheral taste responses to sucrose in mice. PubMed: Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors. PubMed: Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice. PubMed: Bitterness of the non-nutritive sweetener acesulfame potassium varies with polymorphisms in TAS2R9 and TAS2R31. PubMed: Effect of sweeteners and hydrocolloids on quality attributes of reduced-calorie carrot juice. PubMed: Lack of functionally active sweet taste receptors in the jejunum in vivo in the rat. PubMed: Validation of the Korean Addenbrooke's Cognitive Examination for diagnosing Alzheimer's dementia and mild cognitive impairment in the Korean elderly. PubMed: Bitterness prediction of H1-antihistamines and prediction of masking effects of artificial sweeteners using an electronic tongue. PubMed: Effect of the artificial sweetener, acesulfame potassium, a sweet taste receptor agonist, on glucose uptake in small intestinal cell lines. PubMed: Anticonvulsant activity of artificial sweeteners: a structural link between sweet-taste receptor T1R3 and brain glutamate receptors. PubMed: Metabolic acidosis mimicking diabetic ketoacidosis after use of calorie-free mineral water. PubMed: Angiotensin I-converting enzyme inhibitory proteins and peptides from the rhizomes of Zingiberaceae plants. PubMed: Inhibitory activities of baicalin against renin and angiotensin-converting enzyme. PubMed: [Simultaneous determination of six food additives in meat products by high performance liquid chromatography]. PubMed: Rational development of taste masked oral liquids guided by an electronic tongue. PubMed: An electronic tongue: evaluation of the masking efficacy of sweetening and/or flavoring agents on the bitter taste of epinephrine. PubMed: Inadequate toxicity tests of food additive acesulfame. PubMed: General and persistent effects of high-intensity sweeteners on body weight gain and caloric compensation in rats. PubMed: Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo. PubMed: NTP toxicology studies of acesulfame potassium (CAS No. 55589-62-3) in genetically modified (FVB Tg.AC Hemizygous) mice and carcinogenicity studies of acesulfame potassium in genetically modified [B6.129-Trp53(tm1Brd) (N5) Haploinsufficient] mice (feed studies)mice. PubMed: Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2. PubMed: Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. 3rd communication. Behaviour of 5-amino-1H-imidazole-4-carbonitrile derivatives. PubMed: Testing needed for acesulfame potassium, an artificial sweetener. PubMed: Action mechanism of an angiotensin I-converting enzyme inhibitory peptide derived from chicken breast muscle. PubMed: [Analysis of nine kinds of sweeteners in foods by LC/MS]. PubMed: Utility of the ammonia-free Birch reduction of electron-deficient pyrroles: total synthesis of the 20s proteasome inhibitor, clasto-lactacystin beta-lactone. PubMed: Scope of the reductive aldol reaction: application to aromatic carbocycles and heterocycles. PubMed: The powder flow and compact mechanical properties of sucrose and three high-intensity sweeteners used in chewable tablets. PubMed: Determination of acesulfame and sucralose in oral electrolyte maintenance solution by liquid chromatography. PubMed: [Simultaneous determination of various food additives by high performance liquid chromatography]. PubMed: Gustatory responses of the hamster Mesocricetus auratus to various compounds considered sweet by humans. PubMed: Noncariogenic intense natural sweeteners. PubMed: Gustatory neural coding in the monkey cortex: the quality of sweetness.