carbofuran
2,2-dimethyl-7-coumaranyl N-methylcarbamate
Identification
| Name | carbofuran |
| IUPAC | (2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate |
| CAS Number | 1563-66-2 |
| EINECS | 216-353-0 |
| FDA UNII | SKF77S6Y67 |
| Molecular Formula | C12 H15 N O3 |
| Molecular Weight | 221.25615000 |
| MDL Number | MFCD00041819 |
| Nikkaji Number | J3.369C |
| Beilstein | 1428746 |
| XlogP3 | 2.30 (est) |
Regulatory
Physical Properties
| Appearance | white crystalline solid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 151.00 °C. @ 760.00 mm Hg |
| Boiling Point | 313.30 °C. @ 760.00 mm Hg (est) |
| Flash Point | 290.00 °F. TCC ( 143.30 °C. ) (est) |
| logP (o/w) | 2.320 |
| Soluble in | water, 320 mg/L @ 25 °C (exp) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-bird - wild LD50 420 ug/kg |
| Dermal Toxicity | skin-bird - wild LD50 100 mg/kg |
| Inhalation Toxicity | inhalation-dog LC50 52 mg/m3 |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: ATAXIA\nBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD\nPERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE', 'U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#11280']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for carbofuran usage levels up to | not for fragrance use. |
| Recommendation for carbofuran flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
bayer 70143
benzofuran-7-ol, 2,3-dihydro, 2,2-dimethyl, N-methylcarbamate
7-
benzofurano, 2,3-dihydro-2,2-dimethyl, methylcarbamate
7-
benzofuranol, 2,3-dihydro-2,2-dimethyl-, 7-(N-methylcarbamate)
7-
benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate
brifur
carbamic acid, methyl-, 2, 3-dihydro-2,2-dimethyl-7-benzofuranyl ester
carbamic acid, methyl-, 2,2-dimethyl-2, 3-dihydrobenzofuran-7-yl ester
carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester
carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester
carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
carbodan
carbofurane
chinufur
crisfuran
curaterr
2,3-
dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate
2,3-
dihydro-2,2-dimethyl-7-benzofuranol N-methylcarbamate
2,3-
dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate
2,3-
dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate
2,3-
dihydro-2,2-dimethylbenzofuranyl-7-N-methylcarbamate
2,2-
dimethyl-2,2-dihydrobenzofuranyl-7 N-methylcarbamate
2,2-
dimethyl-2,3-dihydro-1-benzofuran-7-yl hydrogen methylcarbonimidate
2,2-
dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate
2,2-
dimethyl-2,3-dihydro-1-benzofuran-7-yl N-methylcarbamate
2,2-
dimethyl-2,3-dihydro-7-benzofuranyl N-methylcarbamate
2,2-
dimethyl-2,3-dihydro-7-benzofuranyl-N-methylcarbamate
2,2-
dimethyl-2,3-dihydrobenzoduranyl-7-N-methylcarbamate
2,2-
dimethyl-2,3-dihydrobenzofuran-7-yl methylcarbamate
(2,2-
dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate
2,2-
dimethyl-7-coumaranyl N-methylcarbamate
(2,2-
dimethyl(2,3-dihydrobenzo[2,3-b]furan-7-yloxy))-N-methylcarboxamide
furacarb
furadan 3G
furadan G
furadane
furodan
karbofuranu
kenofuran
methanol, 1-[(2,3-dihydro-2,2-dimethyl-7-benzofuranyl)oxy]-1-(methylimino)-, (E)-
methyl carbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
niagara 10242
pillarfuran
yaltox
PubMed:
Determination of carbamate and organophosphorus pesticides in vegetable samples and the efficiency of gamma-radiation in their removal.
PubMed:
Protective effect of secondary plant metabolites from Ipomoea aquatica Forsk. against carbofuran induced damages.
PubMed:
Electrochemical nonenzymatic sensor based on CoO decorated reduced graphene oxide for the simultaneous determination of carbofuran and carbaryl in fruits and vegetables.
PubMed:
Evaluation of hepatotoxicity and clastogenicity of carbofuran in male Wistar rats.
PubMed:
High-Throughput Screening and Confirmation of 22 Banned Veterinary Drugs in Feedstuffs Using LC-MS/MS and High-Resolution Orbitrap Mass Spectrometry.
PubMed:
Survey of pesticide application on vegetables in the Littoral area of Togo.
PubMed:
Amperometric immunosensor for carbofuran detection based on MWCNTs/GS-PEI-Au and AuNPs-antibody conjugate.
PubMed:
Laccase-Prussian blue film-graphene doped carbon paste modified electrode for carbamate pesticides quantification.
PubMed:
Bacterial sensors based on biosilica immobilization for label-free OWLS detection.
PubMed:
Organophosphorus and carbamate pesticide residues detected in water samples collected from paddy and vegetable fields of the Savar and Dhamrai Upazilas in Bangladesh.
PubMed:
Acetylcholinesterase biosensor based on chitosan/prussian blue/multiwall carbon nanotubes/hollow gold nanospheres nanocomposite film by one-step electrodeposition.
PubMed:
Comparative effect of pesticides on brain acetylcholinesterase in tropical fish.
PubMed:
Interactions with DOM and biofilms affect the fate and bioavailability of insecticides to invertebrate grazers.
PubMed:
A novel and highly sensitive acetyl-cholinesterase biosensor modified with hollow gold nanospheres.
PubMed:
Total diet study on pesticide residues in France: levels in food as consumed and chronic dietary risk to consumers.
PubMed:
Occurrence of organophosphorus and carbamate pesticide residues in surface water samples from the Rangpur district of Bangladesh.
PubMed:
Chromogenic platform based on recombinant Drosophila melanogaster acetylcholinesterase for visible unidirectional assay of organophosphate and carbamate insecticide residues.
PubMed:
Amperometric immunosensor based on a protein A/deposited gold nanocrystals modified electrode for carbofuran detection.
PubMed:
A label-free electrochemical immunosensor for carbofuran detection based on a sol-gel entrapped antibody.
PubMed:
Sequential injection-bead injection-lab-on-valve coupled to high-performance liquid chromatography for online renewable micro-solid-phase extraction of carbamate residues in food and environmental samples.
PubMed:
Disposable screen-printed electrode coupled with recombinant Drosophila melanogaster acetylcholinesterase and multiwalled carbon nanotubes for rapid detection of pesticides.
PubMed:
Dispersive liquid-liquid microextraction coupled with high-performance liquid chromatography-diode array detection for the determination of N-methyl carbamate pesticides in vegetables.
PubMed:
Enhanced pesticide sensitivity of novel housefly acetylcholinesterases: a new tool for the detection of residual pesticide contamination.
PubMed:
Survey of pesticide residues in maize, cowpea and millet from northern Cameroon: part I.
PubMed:
Monitoring of pesticide residues in vegetables marketed in Al-Qassim region, Saudi Arabia.
PubMed:
Organ-specific ATPase and phosphorylase enzyme activities in a food fish exposed to a carbamate insecticide and recovery response.
PubMed:
Development, validation and application of a methodology based on solid-phase micro extraction followed by gas chromatography coupled to mass spectrometry (SPME/GC-MS) for the determination of pesticide residues in mangoes.
PubMed:
Determination of four carbamate pesticides in corn by cloud point extraction and high-performance liquid chromatography in the visible region based on their derivatization reaction.
PubMed:
Pesticide extraction from table grapes and plums using ionic liquid based dispersive liquid-liquid microextraction.
PubMed:
Ionic liquid based dispersive liquid-liquid microextraction for the extraction of pesticides from bananas.
PubMed:
Cloning, expression, and identification of anti-carbofuran single chain Fv gene.
PubMed:
Effects of exposure to oxamyl, carbofuran, dichlorvos, and lindane on acetylcholinesterase activity in the gills of the Pacific oyster Crassostrea gigas.
PubMed:
Gold immunochromatographic assay for simultaneous detection of carbofuran and triazophos in water samples.
PubMed:
[Determination of carbofuran residue in aquatic products by gas chromatography].
PubMed:
Development of a bispecific monoclonal antibody to pesticide carbofuran and triazophos using hybrid hybridomas.
PubMed:
Tumor promoting and co-carcinogenic effects in medium-term rat hepatocarcinogenesis are not modified by co-administration of 12 pesticides in mixture at acceptable daily intake.
PubMed:
Determination of carbamates in nature water based on the enhancement of electrochemiluminescent of Ru(bpy)(3)(2+) at the multi-wall carbon nanotube-modified electrode.
PubMed:
Rapid hydrolysis and electrochemical detection of trace carbofuran at a disposable heated screen-printed carbon electrode.
PubMed:
Atmospheric pressure glow discharge desorption mass spectrometry for rapid screening of pesticides in food.
PubMed:
Development of an enzyme-linked immuno-sorbent assay (ELISA) method for carbofuran residues.
PubMed:
Determination of 23 pesticide residues in leafy vegetables using gas chromatography-ion trap mass spectrometry and analyte protectants.
PubMed:
[Study on usage of pesticides in various countries].
PubMed:
[Behavior of N-methylcarbamate pesticides during refinement processing of edible oils].
PubMed:
Dissipation of carbofuran and carbaryl on Oolong tea during tea bushes, manufacturing and roasting processes.
PubMed:
Multi-residue determination of pesticides in water using multi-walled carbon nanotubes solid-phase extraction and gas chromatography-mass spectrometry.
PubMed:
Comparative evaluation of acetylcholinesterase status and genome damage in blood cells of industrial workers exposed to carbofuran.
PubMed:
Quantitative determination of diuron in ground and surface water by time-resolved fluoroimmunoassay: seasonal variations of diuron, carbofuran, and paraquat in an agricultural area.
PubMed:
Liquid chromatography quadrupole time-of-flight mass spectrometry analysis of carbosulfan, carbofuran, 3-hydroxycarbofuran, and other metabolites in food.
PubMed:
The delayed genotoxic effect of N-nitroso N-propoxur insecticide in mammalian cells.
PubMed:
Effects of combined and sequential addition of dual oxidants (H2O2/S2O8(2-)) on the aqueous carbofuran photodegradation.
PubMed:
Survey of carbamate and organophosphorous pesticide export from a south Florida (U.S.A.) agricultural watershed: implications of sampling frequency on ecological risk estimation.
PubMed:
Carbofuran sorption kinetics by corn crop soils.
PubMed:
High-sensitivity detection for model organophosphorus and carbamate pesticide with quartz crystal microbalance-precipitation sensor.
PubMed:
Development of controlled release formulations of carbofuran and evaluation of their efficacy against Meloidogyne incognita.
PubMed:
N-methyl carbamate pesticide residues in conventional and organic infant foods available on the Canadian retail market, 2001-03.
PubMed:
Determination of pesticides in soy-based infant formula using liquid chromatography with electrospray ionization tandem mass spectrometry.
PubMed:
Sorption of carbofuran and diuron pesticides in 43 tropical soils of Sri Lanka.
PubMed:
Influence of micelles on the basic degradation of carbofuran.
PubMed:
Use of bentonite and activated carbon in controlled release formulations of carbofuran.
PubMed:
Determination of carbofuran by flow-injection with chemiluminescent detection.
PubMed:
Occupational exposure to carbofuran and the incidence of cancer in the Agricultural Health Study.
PubMed:
Determination of pesticides in apple-based infant foods using liquid chromatography electrospray ionization tandem mass spectrometry.
PubMed:
High-performance liquid chromatography multiresidue method for the determination of N-methyl carbamates in fruit and vegetable juices.
PubMed:
Nanocolloidal gold-based immunoassay for the detection of the N-methylcarbamate pesticide carbofuran.
PubMed:
Soil photolysis in a moisture- and temperature-controlled environment. 2. Insecticides.
PubMed:
Sphingomonas sp. strain SB5 degrades carbofuran to a new metabolite by hydrolysis at the furanyl ring.
PubMed:
Assessment of pesticide residues in honey samples from portugal and Spain.
PubMed:
Multiresidue screening methods for the determination of pesticides in tomatoes.
PubMed:
Competitive degradation and detoxification of carbamate insecticides by membrane anodic Fenton treatment.
PubMed:
Continuous ultrasound-assisted extraction coupled to on line filtration-solid-phase extraction-column liquid chromatography--post column derivatisation-fluorescence detection for the determination of N-methylcarbamates in soil and food.
PubMed:
Influence of suspended solids on acute toxicity of carbofuran to Daphnia magna: II. An evaluation of potential interactive mechanisms.
PubMed:
Carbofuran residue in water chestnut.
PubMed:
Chemiluminescence determination of carbofuran and promecarb by flow injection analysis using two photochemical reactions.
PubMed:
Determination of pesticide residues in nonfatty foods by supercritical fluid extraction and gas chromatography/mass spectrometry: collaborative study.
PubMed:
Comparison of solid-phase extraction and solid-phase microextraction for carbofuran in water analyzed by high-performance liquid chromatography-photodiode-array detection.
PubMed:
Monitoring of pesticide residues on cucumber, tomatoes and strawberries in Gaza Governorates, Palestine.
PubMed:
Effect of insecticides used in corn, sorghum, and alfalfa on the predator Orius insidiosus (Hemiptera: Anthocoridae).
PubMed:
N-nitrosocarbofuran, but not carbofuran, induces apoptosis and cell cycle arrest in CHL cells.
PubMed:
Determination of organophosphate and carbamate pesticides in spiked samples of tap water and fruit juices by a biosensor with photothermal detection.
PubMed:
Validation of a monoclonal enzyme immunoassay for the determination of carbofuran in fruits and vegetables.
PubMed:
Influence of insecticides on microbial transformation of nitrogen and phosphorus in Typic Orchragualf soil.
PubMed:
Development of monoclonal antibody-based immunoassays to the N-methylcarbamate pesticide carbofuran.
PubMed:
Controlled release of carbofuran from an alginate-bentonite formulation: water release kinetics and soil mobility.
PubMed:
Enzyme inhibition and enzyme-linked immunosorbent assay methods for carbamate pesticide residue analysis in fresh produce.
PubMed:
Kuwait's total diet study: dietary intake of organochlorine, carbamate, benzimidazole and phenylurea pesticide residues.
PubMed:
Chemical models of cytochrome P450 catalyzed insecticide metabolism. Application to the oxidative metabolism of carbamate insecticides.
PubMed:
Solid phase microextraction of pesticide residues from strawberries.
PubMed:
The impact of rice pesticides on the aquatic ecosystems of the Sacramento River and Delta (California).
PubMed:
Supercritical fluid extraction of pesticides from meat: a systematic approach for optimisation.
PubMed:
Reproductive efficiency in mink (Mustela vison) treated with the pesticides lindane, carbofuran and pentachlorophenol.
PubMed:
[Study on the determination of N-methylcarbamate insecticides in milk by HPLC].
PubMed:
Behavioral effects of waterborne carbofuran in goldfish.
PubMed:
Characterization of the expression of the thcB gene, coding for a pesticide-degrading cytochrome P-450 in Rhodococcus strains.
PubMed:
CO2 production in three earthworm species exposed to terbuthylazine and carbofuran in food.
PubMed:
Environmental pollutants alter taste responses in the gerbil.
PubMed:
Fate of carbofuran and its effects on aquatic macroinvertebrates in Canadian prairie parkland ponds.
PubMed:
Carbofuran poisoning in herons: diagnosis using cholinesterase reactivation techniques.
PubMed:
Effects of fenamiphos, carbofuran, and aldicarb on zearalenone production by toxigenic Fusarium spp. contaminating roots and fruits of tomato.
PubMed:
Use of a Gammarus pulex bioassay to measure the effects of transient carbofuran runoff from farmland.
PubMed:
Carbofuran toxicity.
PubMed:
Bioavailability to rats and toxicity in mice of carbofuran residues bound to faba beans.
PubMed:
Atrazine, alachlor, and carbofuran contamination of well water in central Maine.
PubMed:
Simulated field ingestion of carbofuran-contaminated feedstuffs by pheasants.
PubMed:
A review of insecticide poisonings among domestic livestock in southern Ontario, Canada, 1982-1989.
PubMed:
Determination of carbofuran by GLC/NPD and HPLC in tomato fruits.
PubMed:
Factors influencing discrimination between insecticide-treated and untreated foods by northern bobwhite.
PubMed:
High-performance liquid chromatographic determination of aryl N-methylcarbamate residues using post-column hydrolysis electrochemical detection.
PubMed:
Bacterial metabolism of carbofuran.
PubMed:
Two methods for evaluating avian food avoidance data.
PubMed:
[Complex hygienic standardization of furadan in reservoir water and in food products].
PubMed:
Insecticide residues in commercially-grown quick-maturing carrots.
PubMed:
Liquid chromatographic determination of N-methylcarbamate insecticides and metabolites in crops. II. Analytical characteristics and residue findings.
PubMed:
Worker reentry research for carbosulfan applied to California citrus trees.
PubMed:
Determination of carbosulfan and carbofuran residues in plants, soil, and water by gas chromatography.
PubMed:
Residues of carbofuran and its two carbamate metabolites in field-treated rutabaga.
PubMed:
Extraction of biologically incorporated [14C]Carbofuran residues from root crops.
PubMed:
Direct analysis of carbofuran and its carbamate metabolites in rapeseed plants by nitrogen-phosphorus detector gas chromatography.
PubMed:
Effects of carbamates on bobwhite food intake, body weight, and locomotor activity.
PubMed:
Isolation and identification of a new conjugated carbofuran metabolite in carrots: angelic acid ester of 3-hydroxycarbofuran.
PubMed:
Direct analysis of carbofuran and 3-hydroxycarbofuran in rape plants by reverse-phase high-pressure liquid chromatography.
PubMed:
Determination of carbofuran and 3-hydroxycarbofuran residues in plant tissue by nitrogen selective gas chromatography.
PubMed:
Direct analysis of carbofuran and two nonconjugated metabolites in crops by high-pressure liquid chromatography with UV absorption detection.
PubMed:
Formation of the N-trifluoroacetate of carbofuran.
PubMed:
Determination of the phenolic metabolites of carbofuran in plant and animal matrices by gas chromatography of their 2,4-dinitrophenyl ether derivatives.
PubMed:
Bioavailability in rats of bound and conjugated plant carbamate insecticide residues.
PubMed:
Fate of carbofuran and its metabolites on strawberries in the environment.
PubMed:
Persistence and biodegradation of carbofuran in flooded soils.
PubMed:
Persistence of some insecticides in subtropical soil.
PubMed:
Effects of light on the fate of carbofuran during the drying of alfalfa.
PubMed:
Distribution of insecticide residues in carrots at harvest.
PubMed:
Esters of sulfonic acids as derivatives for the gas chromatographic analysis of carbamate pesticides.
PubMed:
Determination of carbofuran and its toxic metabolites in animal tissue by gas chromatography of their N-trifluoroacetyl derivatives.
PubMed:
Persistence in soil and losses in runoff of soil-incorporated carbaryl in a small watershed.
PubMed:
Carbofuran. Comparative toxicity and metabolism in the worms Lumbricus terrestris L. and Eisenia foetida S.
PubMed:
Metabolism of carbofuran in mugho pine.
PubMed:
Fate of carbofuran in a model ecosystem.
PubMed:
Dissipation of soil-incorporated carbofuran in the field.
PubMed:
Selective toxicity of N-sulfenylated derivatives of insecticidal methylcarbamate esters.
PubMed:
Determination of carbofuran and 3-hydroxycarbofuran residues in small fruits.
PubMed:
Carbofuran: its toxicity to and metabolism by earthworm (Lumbricus terrestris).
PubMed:
Evaluation of extraction procedures for the removal of 14 C-carbofuran and its toxic metabolites from cabbage leaves.
PubMed:
Inhibition of acetylcholinesterase from mammals and insects by carbofuran and its related compounds and their toxicities toward these animals.
PubMed:
Insecticide inhibition of herbicide metabolism in leaf tissues.
PubMed:
Metabolism of carbofuran alfalfa residues in the dairy cow.