propyzamide
benzamide, 3,5-dichloro-N-(1,1-dimethyl-2-propynyl)-
Identification
| Name | propyzamide |
| IUPAC | 3,5-dichloro-N-(2-methylbut-3-yn-2-yl)benzamide |
| CAS Number | 23950-58-5 |
| EINECS | 245-951-4 |
| FDA UNII | 2EZ95375S0 |
| Molecular Formula | C12 H11 Cl2 N O |
| Molecular Weight | 256.12987000 |
| MDL Number | MFCD00055346 |
| Nikkaji Number | J1.873B |
| Beilstein | 0882391 |
Regulatory
Physical Properties
| Appearance | white solid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 155.00 °C. @ 760.00 mm Hg |
| Boiling Point | 340.90 °C. @ 760.00 mm Hg (est) |
| Flash Point | 320.00 °F. TCC ( 160.00 °C. ) (est) |
| logP (o/w) | 3.430 |
| Soluble in | water, 15 mg/L @ 25 °C (exp) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-dog LD50 10000 mg/kg |
| Dermal Toxicity | skin-rabbit LDLo > 3160 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for propyzamide usage levels up to | not for fragrance use. |
| Recommendation for propyzamide flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
benzamide, 3,5-dichloro-N-(1,1-dimethyl-2-propyn-1-yl)-
benzamide, 3,5-dichloro-N-(1,1-dimethyl-2-propynyl)-
clanex
3,5-
dichlor-N-(2-methyl-3-butin-2-yl)benzamid
3,5-
dichlor-N-(2-methylbut-3-in-2-yl)benzamid
3,5-
dichloro-N-(1,1-dimethyl-2-propynyl) benzamide
3,5-
dichloro-n-(1,1-dimethyl-2-propynyl)benzamide
3,5-
dichloro-N-(1,1-dimethyl-prop-2-ynyl)-benzamide
3,5-
dichloro-N-(1,1-dimethylprop-2-yn-1-yl)benzamide
3,5-
dichloro-N-(1,1-dimethylprop-2-ynyl)benzamide
3,5-
dichloro-N-(1,1-dimethylpropynyl)benzamide
3,5-
dichloro-N-(2-methyl-3-butyn-2-yl)benzamide
3,5-
dichloro-N-(2-methylbut-3-yn-2-yl)benzamide
3,5-
dichloro(N-1,1-dimethyl-2-propynyl)benzamide
(3,5-
dichlorophenyl)-N-(1,1-dimethylprop-2-ynyl)carboxamide
kerb 50W
pronamid
pronamide
propisamide
propizamide
PubMed:
Aphidicolin-Induced Nuclear Elongation in Tobacco BY-2 cells.
PubMed:
Community air monitoring for pesticides-part 2: multiresidue determination of pesticides in air by gas chromatography, gas chromatography-mass spectrometry, and liquid chromatography-mass spectrometry.
PubMed:
Phosphatidic acid integrates calcium signaling and microtubule dynamics into regulating ABA-induced stomatal closure in Arabidopsis.
PubMed:
Influence of an intensive agricultural drainage basin on the seasonal distribution of organic pollutants in seawater from a Mediterranean coastal lagoon (Mar Menor, SE Spain).
PubMed:
An atypical tubulin kinase mediates stress-induced microtubule depolymerization in Arabidopsis.
PubMed:
Modulation of root-skewing responses by KNAT1 in Arabidopsis thaliana.
PubMed:
Environmental fate of fungicides and other current-use pesticides in a central California estuary.
PubMed:
Hazard-ranking of agricultural pesticides for chronic health effects in Yuma County, Arizona.
PubMed:
Mechanism of microtubule array expansion in the cytokinetic phragmoplast.
PubMed:
α-tubulin is rapidly phosphorylated in response to hyperosmotic stress in rice and Arabidopsis.
PubMed:
Pesticide leaching from two Swedish topsoils of contrasting texture amended with biochar.
PubMed:
Seasonal input of regulated and emerging organic pollutants through surface watercourses to a Mediterranean coastal lagoon.
PubMed:
Predicting rapid herbicide leaching to surface waters from an artificially drained headwater catchment using a one dimensional two-domain model coupled with a simple groundwater model.
PubMed:
Micronucleation by mitosis inhibitors in developing microspores of Spathiphyllum wallisii Regel.
PubMed:
NIMA-related kinases regulate directional cell growth and organ development through microtubule function in Arabidopsis thaliana.
PubMed:
Measurement and conceptual modelling of herbicide transport to field drains in a heavy clay soil with implications for catchment-scale water quality management.
PubMed:
Acquisition of embryogenic competency does not require cell division in carrot somatic cell.
PubMed:
Lipid body biogenesis and the role of microtubules in lipid synthesis in Ornithogalum umbellatum lipotubuloids.
PubMed:
Salt stress-induced disassembly of Arabidopsis cortical microtubule arrays involves 26S proteasome-dependent degradation of SPIRAL1.
PubMed:
NIMA-related kinases 6, 4, and 5 interact with each other to regulate microtubule organization during epidermal cell expansion in Arabidopsis thaliana.
PubMed:
Use of farming and agro-industrial wastes as versatile barriers in reducing pesticide leaching through soil columns.
PubMed:
Tobacco microtubule-associated protein, MAP65-1c, bundles and stabilizes microtubules.
PubMed:
Blockage of mitosis in maize root tips using colchicine-alternatives.
PubMed:
Enhanced dissipation of oxyfluorfen, ethalfluralin, trifluralin, propyzamide, and pendimethalin in soil by solarization and biosolarization.
PubMed:
Actin reorganization underlies phototropin-dependent positioning of nuclei in Arabidopsis leaf cells.
PubMed:
Predictive modeling of a mixture of thyroid hormone disrupting chemicals that affect production and clearance of thyroxine.
PubMed:
Photocatalytic degradation of eight pesticides in leaching water by use of ZnO under natural sunlight.
PubMed:
Arabidopsis mitogen-activated protein kinase MPK18 mediates cortical microtubule functions in plant cells.
PubMed:
Arabidopsis microtubule-associated protein AtMAP65-2 acts as a microtubule stabilizer.
PubMed:
Salt tolerance requires cortical microtubule reorganization in Arabidopsis.
PubMed:
Excessive expression of the plant kinesin TBK5 converts cortical and perinuclear microtubules into a radial array emanating from a single focus.
PubMed:
Cell cycle synchronization of tobacco BY-2 cells.
PubMed:
Molecular cloning and gene expression of a fibrillarin homolog of tobacco BY-2 cells.
PubMed:
Change in the actin cytoskeleton during seismonastic movement of Mimosa pudica.
PubMed:
The WAG1 and WAG2 protein kinases negatively regulate root waving in Arabidopsis.
PubMed:
Narrowing of the preprophase microtubule band is not required for cell division plane determination in cultured plant cells.
PubMed:
Isolation of a protein interacting with Vfphot1a in guard cells of Vicia faba.
PubMed:
Loss-of-function mutations of ROOT HAIR DEFECTIVE3 suppress root waving, skewing, and epidermal cell file rotation in Arabidopsis.
PubMed:
Localization of actin filaments on mitotic apparatus in tobacco BY-2 cells.
PubMed:
Does the effect of herbicide pulse exposure on aquatic plants depend on Kow or mode of action?
PubMed:
In vivo dynamics and differential microtubule-binding activities of MAP65 proteins.
PubMed:
Low concentrations of propyzamide and oryzalin alter microtubule dynamics in Arabidopsis epidermal cells.
PubMed:
Complete mineralization of propyzamide in aqueous solution containing TiO2 particles and H2O2 by the simultaneous irradiation of light and ultrasonic waves.
PubMed:
Sonochemical preparation of composite nanoparticles of Au/gamma-Fe2O3 and magnetic separation of glutathione.
PubMed:
A semidominant mutation in an Arabidopsis mitogen-activated protein kinase phosphatase-like gene compromises cortical microtubule organization.
PubMed:
The Arabidopsis sku6/spiral1 gene encodes a plus end-localized microtubule-interacting protein involved in directional cell expansion.
PubMed:
Microtubules and microfilaments coordinate to direct a fountain streaming pattern in elongating conifer pollen tube tips.
PubMed:
Is microtubule disassembly a trigger for cold acclimation?
PubMed:
Involvement of microtubules in rhizoid differentiation of Spirogyra species.
PubMed:
Visualization of peroxisomes in living plant cells reveals acto-myosin-dependent cytoplasmic streaming and peroxisome budding.
PubMed:
DNA catenations that link sister chromatids until the onset of anaphase are maintained by a checkpoint mechanism.
PubMed:
Simultaneous visualization of peroxisomes and cytoskeletal elements reveals actin and not microtubule-based peroxisome motility in plants.
PubMed:
Sub-cellular localisation of GFP-tagged tobacco mitotic cyclins during the cell cycle and after spindle checkpoint activation.
PubMed:
Preparative-scale synthesis of two metabolites isolated from soil treated with zoxium fungicide and kerb herbicide.
PubMed:
Involvement of cortical microtubules in plastic extension regulated by gibberellin in Lemna minor root.
PubMed:
The role of microtubules in guard cell function.
PubMed:
Ruminations regarding the design of small mixtures for biological testing.
PubMed:
The SPIRAL genes are required for directional control of cell elongation in Aarabidopsis thaliana.
PubMed:
Covalent binding of the benzamide RH-4032 to tubulin in suspension-cultured tobacco cells and its application in a cell-based competitive-binding assay.
PubMed:
Simultaneous determination of acidic and non-acidic pesticides in natural waters by liquid chromatography-mass spectrometry.
PubMed:
Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro.
PubMed:
Soil dissipation of diuron, chlorotoluron, simazine, propyzamide, and diflufenican herbicides after repeated applications in fruit tree orchards.
PubMed:
Microtubule stabilization leads to growth reorientation in Arabidopsis trichomes.
PubMed:
Plant cell biology through the window of the highly synchronized tobacco BY-2 cell line.
PubMed:
Indomethacin-induced G1/S phase arrest of the plant cell cycle.
PubMed:
A low content in zeatin type cytokinins is not restrictive for the occurrence of G1/S transition in tobacco BY-2 cells.
PubMed:
Dinitroaniline herbicide-resistant transgenic tobacco plants generated by co-overexpression of a mutant alpha-tubulin and a beta-tubulin.
PubMed:
In situ synthesis of beta-glucan microfibrils on tobacco plasma membrane sheets.
PubMed:
A cell cycle regulated MAP kinase with a possible role in cytokinesis in tobacco cells.
PubMed:
Dynamic organization of microtubules in guard cells of Vicia faba L. with diurnal cycle.
PubMed:
Ploidy of small individual embryo-like structures from maize anther cultures treated with chromosome doubling agents and calli derived from them.
PubMed:
Monoclonal antibodies specific for ohmefentanyl.
PubMed:
Ploidy variation of pronamide-treated maize calli during long term culture.
PubMed:
The colR4 and colR15 beta-tubulin mutations in Chlamydomonas reinhardtii confer altered sensitivities to microtubule inhibitors and herbicides by enhancing microtubule stability.
PubMed:
Capillary column gas chromatography with nitrogen-phosphorus detection for determination of nitrogen- and phosphorus-containing pesticides in finished drinking waters: collaborative study.
PubMed:
The use of antimicrotubule herbicides for the production of doubled haploid plants from anther-derived maize callus.
PubMed:
A Dinitroaniline-Resistant Mutant of Eleusine indica Exhibits Cross-Resistance and Supersensitivity to Antimicrotubule Herbicides and Drugs.
PubMed:
Concentrations of the herbicides propyzamide, chlorpropham, and of their metabolites in soil and lettuce under field conditions.
PubMed:
The role of necrosis in hepatocellular proliferation and liver tumors.
PubMed:
Transplantation studies on induced and spontaneous nodules from B6C3F1 mouse liver.
PubMed:
Applicability of a carbamate insecticide multiresidue method for determining additional types of pesticides in fruits and vegetables.
PubMed:
[Effect of application of a herbicide propyzamide into the soil by study of mineralization of glucose 14C(U) and distribution of radioactivity in various fractions of the soil (laboratory and open field tests)].
PubMed:
Enzymatic alterations in mouse hepatic nodules induced by a chlorinated hydrocarbon pesticide.
PubMed:
[Chromatographic determination of propisamide (kerba) in water, soil and plants].
PubMed:
Carcinogenicity of pronamide.
PubMed:
Metabolism of the herbicide pronamide in soil.