dodine
N-dodecylguanidine acetate
Identification
| Name | dodine |
| IUPAC | acetic acid;2-dodecylguanidine |
| CAS Number | 2439-10-3 |
| EINECS | 219-459-5 |
| FDA UNII | 259C423Y98 |
| Molecular Formula | C15 H33 N3 O2 |
| Molecular Weight | 287.44741000 |
| MDL Number | MFCD00034998 |
| Beilstein | 6546960 |
Regulatory
| FDA Mainterm (IAUFC) | 2439-10-3 ; N-DODECYLGUANIDINE ACETATE |
Physical Properties
| Appearance | white crystalline solid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 136.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 1.500000 mmHg @ 1.50 °C. (est) |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w) | 1.150 |
| Soluble in | water, 630 mg/L @ 25 °C (exp) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-duck LD50 1142 mg/kg |
| Dermal Toxicity | skin-guinea pig LDLo 2000 mg/kg |
| Inhalation Toxicity | inhalation-mouse LC50 129 mg/m3/2H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for dodine usage levels up to | not for fragrance use. |
| Recommendation for dodine flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
aadodin
acetic acid;2-dodecylguanidine
carpene
curitan
cyprex
cyprex 65W
dodecyl guanidine monoacetate
dodecylguanidine acetate
N-
dodecylguanidine acetate
dodecylguanidine monoacetate
1-
dodecylguanidinium acetate
doguadine
guanidine, dodecyl-, monoacetate
guanidine, N-dodecyl-, acetate (1:1)
karpen
laurylguanidine acetate
melprex
melprex 65
melprex 65W
questuran
radspor
syllit
syllit 65
tsitrex
venturol
vondodine
PubMed:
Dodine as a protein denaturant: the best of two worlds?
PubMed:
Combined toxicity of pesticide mixtures on green algae and photobacteria.
PubMed:
Evaluation of dodine, fluopyram and penthiopyrad for the management of leaf spot and powdery mildew of tart cherry, and fungicide sensitivity screening of Michigan populations of Blumeriella jaapii.
PubMed:
A novel dodine-free selective medium based on the use of cetyl trimethyl ammonium bromide (CTAB) to isolate Beauveria bassiana, Metarhizium anisopliae sensu lato and Paecilomyces lilacinus from soil.
PubMed:
Determination of dodine in fruit samples by liquid chromatography electrospray ionization-tandem mass spectrometry.
PubMed:
A new effect residual ratio (ERR) method for the validation of the concentration addition and independent action models.
PubMed:
Effect of occupational exposure to multiple pesticides on translocation yield and chromosomal aberrations in lymphocytes of plant workers.
PubMed:
[Analytical method of dodine in agricultural products by LC/MS].
PubMed:
Utility of six fungicides for selective isolation of Evlachovaea sp. and Tolypocladium cylindrosporum.
PubMed:
Evidence for the Predisposition of Fungicide-Resistant Isolates of Venturia inaequalis to a Preferential Selection for Resistance to Other Fungicides.
PubMed:
Management of apple scab (Venturia inaequalis) in Romania based on electronic warnings.
PubMed:
Comment on "Determination of the critical micelle concentration of dodecylguanidine monoacetate (dodine)".
PubMed:
In vitro susceptibility to fungicides by invertebrate-pathogenic and saprobic fungi.
PubMed:
Impact of fungal drug transporters on fungicide sensitivity, multidrug resistance and virulence.
PubMed:
The potential for enhanced fungicide resistance in Beauveria bassiana through strain discovery and artificial selection.
PubMed:
Isolation of Beauveria bassiana and Metarhizium anisopliae var. anisopliae from Boophilus microplus tick (Canestrini, 1887), in Rio de Janeiro State, Brazil.
PubMed:
[Renal dysfunction in chemical plant workers producing dust pesticides].
PubMed:
Humoral and cellular immunity rates in chemical plant workers producing dust pesticides.
PubMed:
Induction of rat liver cytochrome P450 isoenzymes CYP 1A and CYP 2B by different fungicides, nitrofurans, and quercetin.
PubMed:
A new 2D-TLC bioautography method for the discovery of novel antifungal agents To control plant pathogens.
PubMed:
[Bronchial hyperreactivity in chemical plant workers employed in the production of dust pesticides].
PubMed:
Alterations of male Wistar rat jejunum induced by Dodine (n-dodecylguanidine acetate).
PubMed:
The role of respiratory muscles in the impairment of the respiratory system function in the workers of a chemical plant division producing pesticides.
PubMed:
Effects of n-dodecylguanidine on A-type potassium channels: role of external surface charges in channel gating.
PubMed:
[Allergic diseases caused by pesticides: 3 case reports].
PubMed:
Dodecylguanidine monoacetate (dodine) causes severe membrane damage in Pseudomonas syringae above the critical micelle concentration.
PubMed:
Mode of antibacterial action of dodine (dodecylguanidine monoacetate) in Pseudomonas syringae.
PubMed:
Damage to the cytoplasmic membrane and cell death caused by dodine (dodecylguanidine monoacetate) in Pseudomonas syringae ATCC 12271.
PubMed:
Neutrophil function in chemical plant workers employed in the production of dust pesticides.
PubMed:
[Poisoning with monocrotophos, dinocap, diodine and isopropyl alcohol].
PubMed:
Gas-liquid chromatographic method for the determination of dodine in fruit.
PubMed:
Experimental verification of the possibility of in vivo formation of nitrosocompounds upon combined action of dodecylguanidineacetate and sodium nitrite.
PubMed:
[Determination of dodine in selected plant material].
PubMed:
[Antimicrobial properties of dodecylguanidine acetate].
PubMed:
[Film-forming formulation for treating the surgical field].
PubMed:
Carcinogenic effect of a quanidine pesticide administered with sodium nitrite on adult mice and on the offspring after prenatal exposure.
PubMed:
Microbiological mutagenicity studies of pesticides in vitro.
PubMed:
Fatal poisoning with a plant protective containing monocrotophos, dodine and dinocap.
PubMed:
Mutagenic and recombinogenic action of pesticides in Aspergillus nidulans.
PubMed:
The effect of ionic surface-active agents on macroconidial plasma membrane of Fusarium sulphureum.
PubMed:
Formation of mutagenic N-nitroso compounds from the pesticides prometryne, dodine and carbaryl in the presence of nitrite at pH 1.
PubMed:
A gas-liquid chromatographic method for the determination of dodine residues on foods.
PubMed:
Genetic analysis of dodine resistance in Nectria haematococca (syn. Hypomyces solani).
PubMed:
The induction of dodine tolerance in Fusarium oxysporum f. melonis: a technique applicable to the study of the bionomics of soil-borne fungal pathogens.
PubMed:
Radiation-induced resistance to dodine in Hypopyces.
PubMed:
Uptake and binding of dodine acetate by fungal spores.
PubMed:
Acute and chronic toxicity of dodine (n-dodecylguanidine acetate).