N-dodecylguanidine acetate

CAS: 2439-10-3 C15 H33 N3 O2 MW: 287.44741000

Identification

Namedodine
IUPACacetic acid;2-dodecylguanidine
CAS Number2439-10-3
EINECS219-459-5
FDA UNII259C423Y98
Molecular FormulaC15 H33 N3 O2
Molecular Weight287.44741000
MDL NumberMFCD00034998
Beilstein6546960

Regulatory

FDA Mainterm (IAUFC)2439-10-3 ; N-DODECYLGUANIDINE ACETATE

Physical Properties

Appearance white crystalline solid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 136.00 °C. @ 760.00 mm Hg
Vapor Pressure 1.500000 mmHg @ 1.50 °C. (est)
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w) 1.150
Soluble in water, 630 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-duck LD50 1142 mg/kg
Dermal Toxicityskin-guinea pig LDLo 2000 mg/kg
Inhalation Toxicityinhalation-mouse LC50 129 mg/m3/2H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for dodine usage levels up tonot for fragrance use.
Recommendation for dodine flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

aadodin acetic acid;2-dodecylguanidine carpene curitan cyprex cyprex 65W dodecyl guanidine monoacetate dodecylguanidine acetate N- dodecylguanidine acetate dodecylguanidine monoacetate 1- dodecylguanidinium acetate doguadine guanidine, dodecyl-, monoacetate guanidine, N-dodecyl-, acetate (1:1) karpen laurylguanidine acetate melprex melprex 65 melprex 65W questuran radspor syllit syllit 65 tsitrex venturol vondodine PubMed: Dodine as a protein denaturant: the best of two worlds? PubMed: Combined toxicity of pesticide mixtures on green algae and photobacteria. PubMed: Evaluation of dodine, fluopyram and penthiopyrad for the management of leaf spot and powdery mildew of tart cherry, and fungicide sensitivity screening of Michigan populations of Blumeriella jaapii. PubMed: A novel dodine-free selective medium based on the use of cetyl trimethyl ammonium bromide (CTAB) to isolate Beauveria bassiana, Metarhizium anisopliae sensu lato and Paecilomyces lilacinus from soil. PubMed: Determination of dodine in fruit samples by liquid chromatography electrospray ionization-tandem mass spectrometry. PubMed: A new effect residual ratio (ERR) method for the validation of the concentration addition and independent action models. PubMed: Effect of occupational exposure to multiple pesticides on translocation yield and chromosomal aberrations in lymphocytes of plant workers. PubMed: [Analytical method of dodine in agricultural products by LC/MS]. PubMed: Utility of six fungicides for selective isolation of Evlachovaea sp. and Tolypocladium cylindrosporum. PubMed: Evidence for the Predisposition of Fungicide-Resistant Isolates of Venturia inaequalis to a Preferential Selection for Resistance to Other Fungicides. PubMed: Management of apple scab (Venturia inaequalis) in Romania based on electronic warnings. PubMed: Comment on "Determination of the critical micelle concentration of dodecylguanidine monoacetate (dodine)". PubMed: In vitro susceptibility to fungicides by invertebrate-pathogenic and saprobic fungi. PubMed: Impact of fungal drug transporters on fungicide sensitivity, multidrug resistance and virulence. PubMed: The potential for enhanced fungicide resistance in Beauveria bassiana through strain discovery and artificial selection. PubMed: Isolation of Beauveria bassiana and Metarhizium anisopliae var. anisopliae from Boophilus microplus tick (Canestrini, 1887), in Rio de Janeiro State, Brazil. PubMed: [Renal dysfunction in chemical plant workers producing dust pesticides]. PubMed: Humoral and cellular immunity rates in chemical plant workers producing dust pesticides. PubMed: Induction of rat liver cytochrome P450 isoenzymes CYP 1A and CYP 2B by different fungicides, nitrofurans, and quercetin. PubMed: A new 2D-TLC bioautography method for the discovery of novel antifungal agents To control plant pathogens. PubMed: [Bronchial hyperreactivity in chemical plant workers employed in the production of dust pesticides]. PubMed: Alterations of male Wistar rat jejunum induced by Dodine (n-dodecylguanidine acetate). PubMed: The role of respiratory muscles in the impairment of the respiratory system function in the workers of a chemical plant division producing pesticides. PubMed: Effects of n-dodecylguanidine on A-type potassium channels: role of external surface charges in channel gating. PubMed: [Allergic diseases caused by pesticides: 3 case reports]. PubMed: Dodecylguanidine monoacetate (dodine) causes severe membrane damage in Pseudomonas syringae above the critical micelle concentration. PubMed: Mode of antibacterial action of dodine (dodecylguanidine monoacetate) in Pseudomonas syringae. PubMed: Damage to the cytoplasmic membrane and cell death caused by dodine (dodecylguanidine monoacetate) in Pseudomonas syringae ATCC 12271. PubMed: Neutrophil function in chemical plant workers employed in the production of dust pesticides. PubMed: [Poisoning with monocrotophos, dinocap, diodine and isopropyl alcohol]. PubMed: Gas-liquid chromatographic method for the determination of dodine in fruit. PubMed: Experimental verification of the possibility of in vivo formation of nitrosocompounds upon combined action of dodecylguanidineacetate and sodium nitrite. PubMed: [Determination of dodine in selected plant material]. PubMed: [Antimicrobial properties of dodecylguanidine acetate]. PubMed: [Film-forming formulation for treating the surgical field]. PubMed: Carcinogenic effect of a quanidine pesticide administered with sodium nitrite on adult mice and on the offspring after prenatal exposure. PubMed: Microbiological mutagenicity studies of pesticides in vitro. PubMed: Fatal poisoning with a plant protective containing monocrotophos, dodine and dinocap. PubMed: Mutagenic and recombinogenic action of pesticides in Aspergillus nidulans. PubMed: The effect of ionic surface-active agents on macroconidial plasma membrane of Fusarium sulphureum. PubMed: Formation of mutagenic N-nitroso compounds from the pesticides prometryne, dodine and carbaryl in the presence of nitrite at pH 1. PubMed: A gas-liquid chromatographic method for the determination of dodine residues on foods. PubMed: Genetic analysis of dodine resistance in Nectria haematococca (syn. Hypomyces solani). PubMed: The induction of dodine tolerance in Fusarium oxysporum f. melonis: a technique applicable to the study of the bionomics of soil-borne fungal pathogens. PubMed: Radiation-induced resistance to dodine in Hypopyces. PubMed: Uptake and binding of dodine acetate by fungal spores. PubMed: Acute and chronic toxicity of dodine (n-dodecylguanidine acetate).