oxothiazolidine

2-thiazolidinone

CAS: 2682-49-7 C3 H5 N O S MW: 103.14405000

Identification

Nameoxothiazolidine
IUPAC1,3-thiazolidin-2-one
CAS Number2682-49-7
FDA UNIIM6U1ZG59XD
Molecular FormulaC3 H5 N O S
Molecular Weight103.14405000
MDL NumberMFCD01332388
Nikkaji NumberJ134.976G

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 7.153e+004 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin protecting agents

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for oxothiazolidine usage levels up tonot for fragrance use.
Recommendation for oxothiazolidine flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

1,3- thiazolidin-2-one 2- thiazolidinone PubMed: Synthesis and anticancer activity of some new thiopyrano[2,3-d]thiazoles incorporating pyrazole moiety. PubMed: Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization. PubMed: Glucosinolate hydrolysis products in the crucifer Barbarea vulgaris include a thiazolidine-2-one from a specific phenolic isomer as well as oxazolidine-2-thiones. PubMed: Fragment-based drug discovery of 2-thiazolidinones as inhibitors of the histone reader BRD4 bromodomain. PubMed: Synthesis of novel thiazolone-based compounds containing pyrazoline moiety and evaluation of their anticancer activity. PubMed: Diverted total synthesis: preparation of a focused library of latrunculin analogues and evaluation of their actin-binding properties. PubMed: Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells.