oxothiazolidine
2-thiazolidinone
Identification
| Name | oxothiazolidine |
| IUPAC | 1,3-thiazolidin-2-one |
| CAS Number | 2682-49-7 |
| FDA UNII | M6U1ZG59XD |
| Molecular Formula | C3 H5 N O S |
| Molecular Weight | 103.14405000 |
| MDL Number | MFCD01332388 |
| Nikkaji Number | J134.976G |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 7.153e+004 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin protecting agents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for oxothiazolidine usage levels up to | not for fragrance use. |
| Recommendation for oxothiazolidine flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
1,3-
thiazolidin-2-one
2-
thiazolidinone
PubMed:
Synthesis and anticancer activity of some new thiopyrano[2,3-d]thiazoles incorporating pyrazole moiety.
PubMed:
Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization.
PubMed:
Glucosinolate hydrolysis products in the crucifer Barbarea vulgaris include a thiazolidine-2-one from a specific phenolic isomer as well as oxazolidine-2-thiones.
PubMed:
Fragment-based drug discovery of 2-thiazolidinones as inhibitors of the histone reader BRD4 bromodomain.
PubMed:
Synthesis of novel thiazolone-based compounds containing pyrazoline moiety and evaluation of their anticancer activity.
PubMed:
Diverted total synthesis: preparation of a focused library of latrunculin analogues and evaluation of their actin-binding properties.
PubMed:
Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells.