2,4-hexane dione

propionylacetone

CAS: 3002-24-2 C6 H10 O2 MW: 114.14410000

Identification

Name2,4-hexane dione
CAS Number3002-24-2
FDA UNIIFMD32E86EP
Molecular FormulaC6 H10 O2
Molecular Weight114.14410000
Nikkaji NumberJ35.921A
Beilstein1071471

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 160.00 °C. @ 760.00 mm Hg
Vapor Pressure 2.297000 mmHg @ 25.00 °C. (est)
Flash Point 128.00 °F. TCC ( 53.60 °C. ) (est)
logP (o/w) 0.779 (est)
Soluble in water, 3.618e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-mouse LD > 500 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for 2,4-hexane dione usage levels up tonot for fragrance use.
Recommendation for 2,4-hexane dione flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

acetone, propionyl- hexane-2,4-dione 2,4- hexanedione propionylacetone PubMed: Effect of the capping ligand on luminescent erbium(III) β-diketonate single-ion magnets. PubMed: Structure and NIR-luminescence of ytterbium(III) beta-diketonate complexes with 5-nitro-1,10-phenanthroline ancillary ligand: assessment of chain length and fluorination impact. PubMed: Synthesis and structures of tridentate ketoiminate zinc complexes bearing trifluoromethyl substituents that act as L-lactide ring opening polymerization initiators. PubMed: Feruloylacetone as the model compound of half-curcumin: synthesis and antioxidant properties. PubMed: Metal extraction from water and organic solvents into fluorous solvents by fluorinated beta-diketone and its application to the colorimetric analysis of metal ions. PubMed: Quantitative structure-activity relationship studies for prediction of antimicrobial activity of synthesized 2,4-hexadienoic acid derivatives. PubMed: Perfluorocarbon-based liquid-liquid extraction for separation of transition metal ions. PubMed: The role of water in drug-receptor interactions. PubMed: Richness of isomerism in labile octahedral Werner-type cobalt(II) complexes demonstrated by 19F NMR spectroscopy: structure and stability. PubMed: Engineering tumor-targeted gadolinium hexanedione nanoparticles for potential application in neutron capture therapy. PubMed: Amino acid and protein targets of 1,2-diacetylbenzene, a potent aromatic gamma-diketone that induces proximal neurofilamentous axonopathy. PubMed: Analysis of the in vitro inhibition of murine and human tumor cell growth by pyrazole derivatives and a substituted azabicyclo [3.1.0] hexane-2,4-dione. PubMed: Synthesis of the O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine oximes of selected carbonyl compounds and their determination by liquid chromatography with ultraviolet detection. PubMed: Hypolipidemic activity of 6-alkoxycarbonyl-3-aryl-1,3,5- triazabicyclo[3.1.0]hexane-2,4-diones and 2-alkoxycarbonyl-5-aryl-1,3,5-triazine-4,6(1H,5H)-diones in rodents. PubMed: Synthesis, characterization and biodistribution of tris(beta-diketonato)technetium(III) complexes. PubMed: Analogues of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity. PubMed: Effect of hexacarbons on selected lipids in developing rat brain and peripheral nerves. PubMed: Hexahydrocarbon effects on intermediate filament organization in human fibroblasts. PubMed: Further observations on in vitro and in vivo effects of 2,5-hexanedione on glyceraldehyde-3-phosphate dehydrogenase. PubMed: [An experimental study on neurotoxicity of 2,5-hexanedione. Visual and somatosensory cortical evoked potentials in rats]. PubMed: Molecular mechanism of hexane neuropathy: significant differences in pharmacokinetics between 2.3-, 2.4-, and 2.5-hexanedione. PubMed: Ultrastructural studies of the dying-back process. VI. Examination of nerve fibers undergoing giant axonal degeneration in organotypic culture. PubMed: Covalent binding of a neurotoxic n-hexane metabolite: conversion of primary amines to substituted pyrrole adducts by 2,5-hexanedione. PubMed: Urinary excretion of n-hexane metabolites. A comparative study in rat, rabbit and monkey. PubMed: The relationship of glucose utilization and morphological change in the visual system in hexacarbon neuropathy. PubMed: Ultrastructural studies of the dying-back process. V. Axonal neurofilaments accumulate at sites of 2,5-hexanedione application: evidence for nerve fibre dysfunction in experimental hexacarbon neuropathy. PubMed: Adenosine cyclic 3',5',-monophosphate phosphodiesterasr inhibitors. 2.3-Substituted 5,7-dialkylpyrazolo [1,5-a]pyrimidines.