2,4-hexane dione
propionylacetone
Identification
| Name | 2,4-hexane dione |
| CAS Number | 3002-24-2 |
| FDA UNII | FMD32E86EP |
| Molecular Formula | C6 H10 O2 |
| Molecular Weight | 114.14410000 |
| Nikkaji Number | J35.921A |
| Beilstein | 1071471 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 160.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 2.297000 mmHg @ 25.00 °C. (est) |
| Flash Point | 128.00 °F. TCC ( 53.60 °C. ) (est) |
| logP (o/w) | 0.779 (est) |
| Soluble in | water, 3.618e+004 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD > 500 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for 2,4-hexane dione usage levels up to | not for fragrance use. |
| Recommendation for 2,4-hexane dione flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
acetone, propionyl-
hexane-2,4-dione
2,4-
hexanedione
propionylacetone
PubMed:
Effect of the capping ligand on luminescent erbium(III) β-diketonate single-ion magnets.
PubMed:
Structure and NIR-luminescence of ytterbium(III) beta-diketonate complexes with 5-nitro-1,10-phenanthroline ancillary ligand: assessment of chain length and fluorination impact.
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Synthesis and structures of tridentate ketoiminate zinc complexes bearing trifluoromethyl substituents that act as L-lactide ring opening polymerization initiators.
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Feruloylacetone as the model compound of half-curcumin: synthesis and antioxidant properties.
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Metal extraction from water and organic solvents into fluorous solvents by fluorinated beta-diketone and its application to the colorimetric analysis of metal ions.
PubMed:
Quantitative structure-activity relationship studies for prediction of antimicrobial activity of synthesized 2,4-hexadienoic acid derivatives.
PubMed:
Perfluorocarbon-based liquid-liquid extraction for separation of transition metal ions.
PubMed:
The role of water in drug-receptor interactions.
PubMed:
Richness of isomerism in labile octahedral Werner-type cobalt(II) complexes demonstrated by 19F NMR spectroscopy: structure and stability.
PubMed:
Engineering tumor-targeted gadolinium hexanedione nanoparticles for potential application in neutron capture therapy.
PubMed:
Amino acid and protein targets of 1,2-diacetylbenzene, a potent aromatic gamma-diketone that induces proximal neurofilamentous axonopathy.
PubMed:
Analysis of the in vitro inhibition of murine and human tumor cell growth by pyrazole derivatives and a substituted azabicyclo [3.1.0] hexane-2,4-dione.
PubMed:
Synthesis of the O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine oximes of selected carbonyl compounds and their determination by liquid chromatography with ultraviolet detection.
PubMed:
Hypolipidemic activity of 6-alkoxycarbonyl-3-aryl-1,3,5- triazabicyclo[3.1.0]hexane-2,4-diones and 2-alkoxycarbonyl-5-aryl-1,3,5-triazine-4,6(1H,5H)-diones in rodents.
PubMed:
Synthesis, characterization and biodistribution of tris(beta-diketonato)technetium(III) complexes.
PubMed:
Analogues of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity.
PubMed:
Effect of hexacarbons on selected lipids in developing rat brain and peripheral nerves.
PubMed:
Hexahydrocarbon effects on intermediate filament organization in human fibroblasts.
PubMed:
Further observations on in vitro and in vivo effects of 2,5-hexanedione on glyceraldehyde-3-phosphate dehydrogenase.
PubMed:
[An experimental study on neurotoxicity of 2,5-hexanedione. Visual and somatosensory cortical evoked potentials in rats].
PubMed:
Molecular mechanism of hexane neuropathy: significant differences in pharmacokinetics between 2.3-, 2.4-, and 2.5-hexanedione.
PubMed:
Ultrastructural studies of the dying-back process. VI. Examination of nerve fibers undergoing giant axonal degeneration in organotypic culture.
PubMed:
Covalent binding of a neurotoxic n-hexane metabolite: conversion of primary amines to substituted pyrrole adducts by 2,5-hexanedione.
PubMed:
Urinary excretion of n-hexane metabolites. A comparative study in rat, rabbit and monkey.
PubMed:
The relationship of glucose utilization and morphological change in the visual system in hexacarbon neuropathy.
PubMed:
Ultrastructural studies of the dying-back process. V. Axonal neurofilaments accumulate at sites of 2,5-hexanedione application: evidence for nerve fibre dysfunction in experimental hexacarbon neuropathy.
PubMed:
Adenosine cyclic 3',5',-monophosphate phosphodiesterasr inhibitors. 2.3-Substituted 5,7-dialkylpyrazolo [1,5-a]pyrimidines.