Identification

Namecyclopentyl mercaptan
IUPACcyclopentanethiol
CAS Number1679-07-8
EINECS216-841-3
FDA UNIIH279996YO9
Molecular FormulaC5 H10 S
Molecular Weight102.19970000
MDL NumberMFCD00001369
Nikkaji NumberJ43.297K
Beilstein2343861
CoE Number2321

Regulatory

JECFA Food Flavoring516 cyclopentanethiol
DG SANTE Food Flavourings12.029 cyclopentanethiol
FEMA Number3262
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)1679-07-8 ; CYCLOPENTANETHIOL

Physical Properties

Appearance colorless clear liquid (est)
Assay 97.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.92000 to 0.92500 @ 25.00 °C.
Pounds per Gallon - (est). 7.655 to 7.697
Refractive Index 1.48800 to 1.49020 @ 20.00 °C.
Boiling Point 41.00 to 42.00 °C. @ 16.00 mm Hg, 130.00 to 132.00 °C. @ 760.00 mm Hg
Vapor Pressure 1.000000 mmHg @ 20.00 °C.
Vapor Density 1.0 ( Air = 1 )
Flash Point 77.00 °F. TCC ( 25.00 °C. )
logP (o/w) 2.377 (est)
Soluble in alcohol
Insoluble in water
Similar Items note

Organoleptic Properties

Odor Description
at 0.01 % in propylene glycol.
Alliaceous, onion, garlic, horseradish, vegetable-celery, egg, sauteed meat
Taste Description at 2.00 ppm.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-mouse LD50 [sex: M,F (5/group)] 2680 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavoring agents
Recommendation for cyclopentyl mercaptan usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)ND (μg/capita/day)
NOEL (No Observed Effect Level)0.56 (mg/kg bw per day)
Structure ClassII
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

FL egg FL garlic FL horseradish FL meat FL onion

Natural Occurrence

wine

Synonyms

cyclopentane thiol cyclopentanethiol cyclopentyl thiol cyclopentylmercaptan cyclopentylthiol mercaptocyclopentane PubMed: [Inhibitory effect on Microcystis aeruginosa as well as separation and identification of the allelochemicals of welsh onion]. PubMed: Matrix metalloproteinase inhibitors based on the 3-mercaptopyrrolidine core. PubMed: N-(tert)-butyloxycarbonyl)-beta,beta-cyclopentyl-cysteine (acetamidomethyl)-methyl ester for synthesis of novel peptidomimetic derivatives. PubMed: Inhibition of nitric-oxide synthase enhances antigen-induced contractions and increases release of cysteinyl-leukotrienes in guinea pig lung parenchyma: nitric oxide as a protective factor. PubMed: Characterization of a new class of selective nonsteroidal progesterone receptor agonists. PubMed: Glutathione analogues in cancer treatment. PubMed: Does nitric oxide allow endothelial cells to sense hypoxia and mediate hypoxic vasodilatation? In vivo and in vitro studies. PubMed: Intrinsic optical signals in the dorsal horn of rat spinal cord slices elicited by brief repetitive stimulation. PubMed: Serine and alanine mutagenesis of the nine native cysteine residues of the human A(1) adenosine receptor. PubMed: Mechanisms of inhibitory effects of zinc and cadmium ions on agonist binding to adenosine A1 receptors in rat brain. PubMed: CNS adenosine A1 receptors are altered after the administration of convulsant 3-mercaptopropionic acid and cyclopentyladenosine: an autoradiographic study. PubMed: New alpha-thiol dipeptide dual inhibitors of angiotensin-I converting enzyme and neutral endopeptidase EC 3.4.24.11. PubMed: Cysteine esters protect cultured rodent lung slices from sulphur mustard. PubMed: Inhibitory effect of selected antiviral compounds on arenavirus replication in vitro. PubMed: Chemical modification of A1 adenosine receptors in rat brain membranes. Evidence for histidine in different domains of the ligand binding site. PubMed: Angiotensin-converting enzyme inhibitors. New orally active antihypertensive (mercaptoalkanoyl)- and [(acylthio)alkanoyl]glycine derivatives.