toralactone

1H-naphtho[2,3-c]pyran-1-one, 9,10-dihydroxy-7-methoxy-3-methyl-

CAS: 41743-74-2 C15 H12 O5 MW: 272.25664000

Identification

Nametoralactone
IUPAC9,10-dihydroxy-7-methoxy-3-methylbenzo[g]isochromen-1-one
CAS Number41743-74-2
FDA UNIISearch
Molecular FormulaC15 H12 O5
Molecular Weight272.25664000
Nikkaji NumberJ516.545H

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 34.72 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for toralactone usage levels up tonot for fragrance use.
Recommendation for toralactone flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

senna sickle senna seed

Synonyms

9,10- dihydroxy-7-methoxy-3-methyl-1H-naphtho(2,3-c)pyran-1-one 9,10- dihydroxy-7-methoxy-3-methylbenzo[g]isochromen-1-one 1H- naphtho[2,3-c]pyran-1-one, 9,10-dihydroxy-7-methoxy-3-methyl- Google Patents: New toralactone and its derivation and the use of decreasing blood-fat and losing weight PubMed: A new comprehensive procedure for the quality control of Semen Cassiae and its application in evaluating commercially available material in China. PubMed: Structure elucidation of a sodium salified anthraquinone from the seeds of Cassia obtusifolia by NMR technique assisted with acid-alkali titration. PubMed: Extract of Cassiae Semen and its major compound inhibit S100b-induced TGF-beta1 and fibronectin expression in mouse glomerular mesangial cells. PubMed: Inhibitory activities of Cassia tora and its anthraquinone constituents on angiotensin-converting enzyme. PubMed: Antibacterial phenolic components from Eriocaulon buergerianum. PubMed: Estrogenic and anti-estrogenic activities of Cassia tora phenolic constituents. PubMed: Naphthopyrone glucosides from the seeds of Cassia tora with inhibitory activity on advanced glycation end products (AGEs) formation. PubMed: Total synthesis of the antiallergic naphtho-alpha-pyrone tetraglucoside, cassiaside C(2), isolated from cassia seeds. PubMed: Phenolic constituents of Cassia seeds and antibacterial effect of some naphthalenes and anthraquinones on methicillin-resistant Staphylococcus aureus. PubMed: Antiallergic agent from natural sources. Structures and inhibitory effect of histamine release of naphthopyrone glycosides from seeds of Cassia obtusifolia L. PubMed: A new deoxyfusarubin produced by the fungus Nectria haematococca. Synthesis of the two isomeric deoxyanhydronaphthopyranones from toralactone. PubMed: New antihepatotoxic naphtho-pyrone glycosides from the seeds of Cassia tora. PubMed: [Studies on the constituents of the seeds of Cassia tora L. II. (On the purgative crude drugs. VII). The structure of the new naphtho- -pyrone derivative, toralactone].