guanidine phosphate

guanidine, phosphate (1:1)

CAS: 5423-22-3 C H8 N3 O4 P MW: 157.06632200

Identification

Nameguanidine phosphate
IUPACguanidine;phosphoric acid
CAS Number5423-22-3
EINECS226-551-9
FDA UNII2TXI2V75J2
Molecular FormulaC H8 N3 O4 P
Molecular Weight157.06632200
MDL NumberMFCD00066148
Beilstein3709508

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 158.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 1.410000 mmHg @ 25.00 °C. (est)
Flash Point 515.00 °F. TCC ( 268.10 °C. ) (est)
logP (o/w) -2.148 (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin conditioning
Recommendation for guanidine phosphate usage levels up tonot for fragrance use.
Recommendation for guanidine phosphate flavor usage levels up tonot for flavor use.

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Potential Uses

biological additives

Natural Occurrence

not found in nature

Synonyms

amino(imino)methanaminium hydrogen phosphate (1:2:1) guanidine monophosphate guanidine, phosphate (1:1) guanidine;phosphoric acid guanidinephosphate guanidinium dihydrogen phosphate guanidinium phosphate (1:1) guanidiniumdihydrogenphosphate PubMed: Antimicrobial activity of polyhexamethylene guanidine phosphate in comparison to chlorhexidine using the quantitative suspension method. PubMed: Guanidine-phosphate non-covalent interaction in LAP crystal growth solution evidenced from spectroscopy studies. PubMed: Pharmacophore elucidation and molecular docking studies on phosphodiesterase-5 inhibitors. PubMed: Polyhexamethylene guanidine phosphate aerosol particles induce pulmonary inflammatory and fibrotic responses. PubMed: The role of NF-κB signaling pathway in polyhexamethylene guanidine phosphate induced inflammatory response in mouse macrophage RAW264.7 cells. PubMed: Exposure characteristics of familial cases of lung injury associated with the use of humidifier disinfectants. PubMed: Oxidative inhibition of the vascular Na+-K+ pump via NADPH oxidase-dependent β1-subunit glutathionylation: implications for angiotensin II-induced vascular dysfunction. PubMed: [Comparative in vitro antibacterial activity of polyhexamethylene guanidine hydrochloride and polyhexamethylene guanidine succinate]. PubMed: Acute cardiovascular toxicity of sterilizers, PHMG, and PGH: severe inflammation in human cells and heart failure in zebrafish. PubMed: Selenium inhibits renal oxidation and inflammation but not acute kidney injury in an animal model of rhabdomyolysis. PubMed: Survival of microorganisms on antimicrobial filters and the removal efficiency of bioaerosols in an environmental chamber. PubMed: Multiple activities of c-di-GMP in Pseudomonas aeruginosa. PubMed: Influence of menopause on biochemical markers of endothelial dysfunction-A case-control pilot study in North Indian population. PubMed: Compound 48/80 induces endothelium-dependent and histamine release-independent relaxation in rabbit aorta. PubMed: Per(6-guanidino-6-deoxy)cyclodextrins: synthesis, characterisation and binding behaviour toward selected small molecules and DNA. PubMed: Platelet aggregation profile as a marker of hydroxyurea bioavailability through nitric oxide generation in chronic myelogenous leukemia. PubMed: Hypoxia down-regulates cyclic guanidine monophosphate-dependent protein kinase in fetal pulmonary vascular smooth muscle cell through generation of reactive oxygen species and promotes development of pulmonary hypertension. PubMed: Overexpression of C1-tetrahydrofolate synthase in fetal Down syndrome brain. PubMed: Role of nitric oxide in alcohol alteration of beta-endorphin release from hypothalamic cells in primary cultures. PubMed: Intravenous sildenafil is a potent pulmonary vasodilator in children with congenital heart disease. PubMed: Nitric oxide inhibits GABA-evoked current in dorsal root ganglion neuron via PKG-dependent pathway. PubMed: Dry weight in hemodialysis: volemic control. PubMed: The comparison of vascular reactivities of arterial and venous grafts to vasodilators: management of graft spasm. PubMed: Effects of LDL on intracellular free calcium and nitric oxide-dependent cGMP formation in porcine endothelial cells. PubMed: [Leukocyte cytoskeleton under normal and pathological conditions]. PubMed: [Effect of cyclic guanidine monophosphate on experimental wound healing].