aluminum lactate

propanoic acid, 2-hydroxy-, aluminum complex

CAS: 18917-91-4 C9 H15 Al O9 MW: 294.19288860

Identification

Namealuminum lactate
IUPACbis(2-hydroxypropanoyloxy)alumanyl 2-hydroxypropanoate
CAS Number18917-91-4
EINECS242-670-9
FDA UNIIV797H4GG0Z
Molecular FormulaC9 H15 Al O9
Molecular Weight294.19288860

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesastringents

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-rat LD50 3270 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for aluminum lactate usage levels up tonot for fragrance use.
Recommendation for aluminum lactate flavor usage levels up tonot for flavor use.

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Potential Uses

buffering agents

Natural Occurrence

not found in nature

Synonyms

aluminium lactate aluminium lactate (Al(O3C3H5)3) aluminium lacticum aluminium trilactate aluminium tris(2-hydroxypropanoate) aluminium tris(alpha-hydroxypropionate) aluminium, tris(2-hydroxypropanoate-O1,O2)- aluminum lactate (Al(O3C3H5)3) aluminum trilactate aluminum tris(alpha-hydroxypropionate) aluminum, tris(2-hydroxypropanoate-O1,O2)- tris(2- hydroxypropanoato-O(sup 1),O(sup 2))aluminium tris(2- hydroxypropanoato-O(sup 1),O(sup 2))aluminum bis(2- hydroxypropanoyloxy)alumanyl 2-hydroxypropanoate propanoic acid, 2-hydroxy-, aluminium complex propanoic acid, 2-hydroxy-, aluminum complex PubMed: Effects of Chronic Aluminum Lactate Exposure on Neuronal Apoptosis and Hippocampal Synaptic Plasticity in Rats PubMed: Ginkgo biloba attenuates aluminum lactate-induced neurotoxicity in reproductive senescent female rats: behavioral, biochemical, and histopathological study PubMed: Variation in aluminium patch test reactivity over time PubMed: Distribution of aluminium following intraperitoneal injection of aluminium lactate in the rat PubMed: [Effects of subchronic aluminum lactate exposure on learning and memory and transportation of A? in blood-cerebrospinal fluid in rats] PubMed: Differential aluminium lactate toxicity in rabbits using either aqueous solutions or liposomal suspensions PubMed: Concurrent ingestion of lactate and aluminum can result in developmental toxicity in mice PubMed: Aluminum and copper in drinking water enhance inflammatory or oxidative events specifically in the brain PubMed: Green solvents in recovery of aluminium and plastic from waste pharmaceutical blister packaging PubMed: Aluminum distribution into brain and liver of rats and rabbits following intravenous aluminum lactate or citrate: a microdialysis study PubMed: Establishing aluminium contact allergy PubMed: Pathological changes associated with aluminum and zirconium compounds. (An experimental study of skin pathology following the application of aluminum chlorohydroxide, aluminum sulfate, sodium aluminum lactate PubMed: Effects of low-molecular-weight aluminum complexes on brain tissue calcium homeostasis PubMed: Further information on aluminium inhalation in silicosis PubMed: Aluminum inhalation reduces silicosis in a sheep model PubMed: Orchiectomy attenuates oxidative stress induced by aluminum in rats PubMed: Urinary concentrating mechanism and Aquaporin-2 abundance in rats chronically treated with aluminum lactate PubMed: Aluminium inhalation in sheep silicosis PubMed: Developmental alternations in offspring of female rats orally intoxicated by aluminum chloride or lactate during gestation PubMed: Clinical efficacy of desensitizing mouthwashes for the control of dentin hypersensitivity and root sensitivity: a systematic review and meta-analysis PubMed: Aluminium administration is associated with enhanced hepatic oxidant stress that may be offset by dietary vitamin E in the rat PubMed: The plaque and gingivitis reducing effect of a chlorhexidine and aluminium lactate containing dentifrice (Lacalut aktiv) over a period of 6 months PubMed: Accumulation of aluminum in ferritin isolated from rat brain PubMed: Iron status affects aluminum uptake and transport by Caco-2 cells PubMed: Regional accumulation of aluminium in the rat brain is affected by dietary vitamin E PubMed: Clinical evaluation of a dental rinse containing aluminum lactate for treatment of dentinal hypersensitivity PubMed: [Aluminuminduced impairment in primary cultured rat choroid plexus epithelial cells] PubMed: Aluminum toxicity in a molluscan neuron: effects of counterions PubMed: Experimental articular toxicity of aluminum compounds in vivo PubMed: Aluminium lactate treatment of DQ12 quartz inhibits its ability to cause inflammation, chemokine expression, and nuclear factor-kappaB activation PubMed: Glomerular lesions in male rabbits treated with aluminium lactate: with special reference to microaneurysm formation PubMed: The quartz hazard: effects of surface and matrix on inflammogenic activity PubMed: A model of aluminum exposure associated with lipid peroxidation in rat brain PubMed: Fish Oil and Primrose Oil Suppress the Progression of Alzheimer's Like Disease Induced by Aluminum in Rats PubMed: Aluminum lactate treatment alters the lung biological activity of quartz PubMed: Effect of solubility on the gastrointestinal absorption of aluminum from various aluminum compounds in the rat PubMed: Assessing the bioactivity of crystalline silica in heated high-temperature insulation wools PubMed: Aluminum salts induce the accumulation of neurofilaments in perikarya of NB2a/dl neuroblastoma PubMed: Linker histone-DNA complexes: enhanced stability in the presence of aluminum lactate and implications for Alzheimer's disease PubMed: Aluminum induced reversible change in permeability of the blood-brain barrier to [14C]sucrose PubMed: A randomised controlled trial to compare the efficacy of an aluminium lactate/potassium nitrate/hydroxylapatite toothpaste with a control toothpaste for the prevention of dentine hypersensitivity PubMed: Maternal and developmental toxicity of chronic aluminum exposure in mice PubMed: Ligand specific effects on aluminum incorporation and toxicity in neurons and astrocytes PubMed: Aluminum and sulphate removal by a highly Al-resistant dissimilatory sulphate-reducing bacteria community PubMed: Aluminium induced oxidative stress results in decreased mitochondrial biogenesis via modulation of PGC-1à expression PubMed: Aluminum impairs gap junctional intercellular communication between astroglial cells in vitro PubMed: In vivo and in vitro effects of aluminum on the activity of mouse brain acetylcholinesterase PubMed: Bioavailability and intestinal absorption of aluminum in rats: effects of aluminum compounds and some dietary constituents PubMed: Modulatory Effects of Ginkgo biloba Against Amyloid Aggregation Through Induction of Heat Shock Proteins in Aluminium Induced Neurotoxicity PubMed: Sustained efficacy of aluminum to reduce quartz toxicity in the lung PubMed: Aluminum(III) influences the permeability of the blood-brain barrier to [14C]sucrose in rats PubMed: Quercetin protects against aluminium induced oxidative stress and promotes mitochondrial biogenesis via activation of the PGC-1à signaling pathway PubMed: Different particle determinants induce apoptosis and cytokine release in primary alveolar macrophage cultures PubMed: Aluminum promotes neuronal plasticity events in a mouse neuroblastoma cell line PubMed: Developmental alterations in offspring of female rats orally intoxicated by aluminum lactate at different gestation periods PubMed: Effect of prenatal aluminium lactate exposure on conditioned taste aversion and passive avoidance task in the rat PubMed: Decrease of glial fibrillary acidic protein in rat frontal cortex following aluminum treatment PubMed: Element variations in pregnant and nonpregnant female rats orally intoxicated by aluminum lactate PubMed: Evaluation of the effects of aluminium, ethanol and their combination on rat brain synaptosomal integral proteins in vitro and after 90-day oral exposure PubMed: Lack of marked cyto- and genotoxicity of cristobalite in devitrified (heated) alkaline earth silicate wools in short-term assays with cultured primary rat alveolar macrophages PubMed: Physicochemical properties of crystalline silica dusts and their possible implication in various biological responses PubMed: Mineral metabolism of rats fed moderate levels of various aluminum compounds for short periods of time PubMed: [The caries-preventive effect of aluminum fluoride complexes and aluminum lactate in animal experiments] PubMed: Effects of aluminum lactate on murine neuroblastoma cells PubMed: Evaluation of the developmental neuroendocrine and reproductive toxicology of aluminium PubMed: Surface-dependent quartz uptake by macrophages: potential role in pulmonary inflammation and lung clearance PubMed: Melatonin prevents oxidative stress in ovariectomized rats treated with aluminium PubMed: Effects of complexed iron and aluminium on brain calcium PubMed: Surface modification of quartz inhibits toxicity, particle uptake, and oxidative DNA damage in human lung epithelial cells PubMed: Late aluminum therapy reduces the cellular activities of simple silicosis in the sheep model PubMed: Neuronal gene expression in aluminum-induced neurofibrillary pathology: an in situ hybridization study PubMed: Two Randomized Clinical Studies to Confirm Differential Plaque Removal by Sodium Bicarbonate Dentifrices in a Single Timed Brushing Model PubMed: Organosilane-Based Coating of Quartz Species from the Traditional Ceramics Industry: Evidence of Hazard Reduction Using In Vitro and In Vivo Tests PubMed: Aluminium-induced oxidative DNA damage recognition and cell-cycle disruption in different regions of rat brain PubMed: Aluminum inhibits calpain-mediated proteolysis and induces human neurofilament proteins to form protease-resistant high molecular weight complexes PubMed: Synergy between nisin and select lactates against Listeria monocytogenes is due to the metal cations PubMed: Effect of calcitriol infusions on serum aluminum in vitamin D-depleted rabbits fed an aluminum-supplemented ration PubMed: Ubiquitin and heat shock proteins in cultured nervous tissue after different stress conditions PubMed: [Astringent action of aluminum lactate (lacalut) solutions] PubMed: Pro-oxidant activity of aluminum in the rat hippocampus: gene expression of antioxidant enzymes after melatonin administration PubMed: Effects of postnatal aluminum exposure on biological parameters in the rat plasma PubMed: Effects of aluminum on phosphate metabolism in rats: a possible interaction with vitamin D3 renal production PubMed: Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity PubMed: Impaired spatial learning and unaltered neurogenesis in a transgenic model of Alzheimer's disease after oral aluminum exposure PubMed: [Effects of lateral ventricular injection of aluminum lactate on the locomotor activity in rats] PubMed: Experimental aluminum pathology in rabbits: effects of hydrophilic and lipophilic compounds PubMed: Chronic exposure to low levels of aluminum alters cerebral cell signaling in response to acute MPTP administration PubMed: Parenteral aluminum compounds produce a local toxic myopathy in rats: importance of the anion PubMed: Comparative effects of calcitriol and parathyroid hormone on serum aluminum in vitamin D-depleted rabbits fed an aluminum-supplemented diet PubMed: Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity PubMed: DNA damage in lung epithelial cells isolated from rats exposed to quartz: role of surface reactivity and neutrophilic inflammation PubMed: The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung PubMed: Inflammatory time course after quartz instillation: role of tumor necrosis factor-alpha and particle surface PubMed: Multinuclear NMR studies on the sol-gel preparation of sodium aluminophosphate glasses PubMed: Inhibition of rat brain phosphatidylinositol-specific phospholipase C by aluminum: regional differences, interactions with aluminum salts, and mechanisms PubMed: 1H-13C-27Al triple resonance transfer of populations in double resonance experiments for the detection of 13C-27Al dipolar interactions PubMed: Effects of aluminum ingestion on spontaneous motor activity of mice PubMed: Measurement of aluminum-carbon distances using S-RESPDOR NMR experiments PubMed: Effect of the size of an oral dose of aluminium on the relative importance of biliary v. urinary aluminium excretion in conscious rats PubMed: Ehrlich tumour cells: Ca(2+)-uptake modification by aluminium lactate PubMed: Kinetics of aluminum disposition after ingestion of low to moderate pharmacological doses of aluminum PubMed: Bile is an important route of elimination of ingested aluminum by conscious male Sprague-Dawley rats PubMed: Effect of chronic accumulation of aluminum on renal function, cortical renal oxidative stress and cortical renal organic anion transport in rats PubMed: Neurotoxicity induced by prenatal aluminum exposure in rats PubMed: Aluminium effects on thyroid gland function: iodide uptake, hormone biosynthesis and secretion PubMed: Reactivity of lactate-modified nanoscale iron particles with 2,4-dinitrotoluene in soils PubMed: [The study on the relationship between hippocampus neuronal apoptosis and hippocampus synaptic plasticity in rats exposed to aluminum] PubMed: Internalization, cytotoxicity, apoptosis, and tumor necrosis factor-alpha expression in rat alveolar macrophages exposed to various dusts occurring in the ceramics industry PubMed: Clinical comparison of plaque inhibition effects of a novel stabilized stannous fluoride dentifrice and a chlorhexidine digluconate dentifrice using digital plaque imaging PubMed: Effect of aluminum inhalation on alveolar phospholipid profiles in experimental silicosis PubMed: Aluminum-induced neurofilamentous changes in cultured rat dorsal root ganglia explants PubMed: Aluminum alters the electrophoretic properties of neurofilament proteins: role of phosphorylation state PubMed: Evaluation of the protective role of melatonin on the behavioral effects of aluminum in a mouse model of Alzheimer's disease PubMed: The effect of social learning on a conditioned avoidance response of rats treated prenatally with aluminum lactate PubMed: Disruption of neuronal calcium homeostasis after chronic aluminium toxicity in rats PubMed: Oxidative stress status and RNA expression in hippocampus of an animal model of Alzheimer's disease after chronic exposure to aluminum PubMed: Hair as an indicator of excessive aluminum exposure PubMed: Genetic aspects of wheat gliadin proteins PubMed: Chronic exposure to aluminum in drinking water increases inflammatory parameters selectively in the brain PubMed: Phosphorylation and dephosphorylation of histone (V (H5): controlled condensation of avian erythrocyte chromatin. Appendix: Phosphorylation and dephosphorylation of histone H5. II. Circular dichroic studies PubMed: Recognition memory and ?-amyloid plaques in adult Tg2576 mice are not modified after oral exposure to aluminum PubMed: Diminished arachidonic acid metabolite release by bovine alveolar macrophages exposed to surface-modified silica PubMed: Influence of aluminum treatments on pulmonary retention of quartz in sheep silicosis PubMed: A randomized clinical study comparing the plaque inhibition effect of a SnF2/SHMP dentifrice (blend-a-med EXPERT GUMS PROTECTION) and a chlorhexidine digluconate dentifrice (Lacalut Aktiv) PubMed: Effects of postnatal aluminum exposure on choline acetyltransferase activity and learning abilities in the rat PubMed: Aluminium causes variable responses in actin filament cytoskeleton of the root tip cells of Triticum turgidum PubMed: Tris acetylacetonate aluminium(III) induces osmotic fragility and acanthocyte formation in suspended erythrocytes PubMed: Neogenesis of skeletal muscle in the postinflammatory rat peritoneum PubMed: On the experimental use of light metal salts for negative staining PubMed: Protective role of melatonin on oxidative stress status and RNA expression in cerebral cortex and cerebellum of AbetaPP transgenic mice after chronic exposure to aluminum PubMed: Aluminum removal after chronic intoxication in rats PubMed: Reconstitution of the native mitochondrial outer membrane in planar bilayers. Comparison with the outer membrane in a patch pipette and effect of aluminum compounds PubMed: Bronchoalveolar leukocyte response in experimental silicosis: modulation by a soluble aluminum compound PubMed: Does aluminum lactate cause spinal cord infarction in rabbits? PubMed: The effect of aluminum on markers for synaptic neurotransmission, cyclic AMP, and neurofilaments in a neuroblastoma x glioma hybridoma (NG108-15) PubMed: Micro-PIXE (particle induced X-ray emission) analysis of aluminum in rat-liver using MeV heavy ion microprobes PubMed: Long-term oral administration of aluminum in mice. Aluminum distribution in tissues and effects on calcium metabolism PubMed: Alterations in human linker histone-DNA binding in the presence of aluminum salts in vitro and in Alzheimer's disease PubMed: Short-term oral 3-hydroxypyridin-4-one dosing increases aluminum excretion and partially reverses aluminum-induced toxicity in the rabbit independent of chelator lipophilicity PubMed: [Experimental neurofibrillary change induced by aluminum lactate] PubMed: A glutamatergic mechanism for aluminum toxicity in astrocytes PubMed: Effect of aluminum and other multivalent cations on neurofilaments in vitro: an electron microscopic study PubMed: Electrophoresis of gliadins in long acrylamide gels: method and nomenclature PubMed: Effects of postnatal aluminum lactate exposure on neuromotor maturation in the rat PubMed: Preparative fractionation of gliadins by electrophoresis at pH 3.1 (A-PAGE) PubMed: Assessment of genomic and species relationships in Triticum and Aegilops by PAGE and by differential staining of seed albumins and globulins PubMed: Effect of Organic and Inorganic Salts on the Development of Helminthosporium solani, the Causal Agent of Potato Silver Scurf PubMed: A calcium lactate aluminum hydroxide preparation as a preventive for parturient paresis PubMed: A continuous acetic acid system for polyacrylamide gel electrophoresis of gliadins and other prolamines PubMed: Modification of in vivo Ca(2+)-uptake by parenterally administered aluminum complexes PubMed: Ultracytochemical studies of the effects of aluminum on the blood-brain barrier of mice PubMed: Role of lipid peroxidation in ferric lactate-enhanced calcium uptake by Ehrlich carcinoma cells PubMed: Rabbit spinal cord infarctuated upon aluminum (III)-liposomes intravenous treatment PubMed: Brain protein synthesis in rabbits following low level aluminium exposure PubMed: Genetic analysis of gliadin components in winter wheat using two-dimensional polyacrylamide gel electrophoresis PubMed: Activation of monoamine oxidase type-B by aluminum in rat brain homogenate PubMed: 13C-(27)Al TRAPDOR and REDOR experiments for the detection of (13)C-(27)Al dipolar interactions in solids PubMed: Effects of an Agropyron chromosome on endosperm proteins in common wheat Triticum aestivum L.)