Identification

Nameambroxan
IUPAC(3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran
CAS Number6790-58-5
EINECS229-861-2
FDA UNIITD34B3O8M9
Molecular FormulaC16 H28 O
Molecular Weight236.39836000
MDL NumberMFCD00134491
Nikkaji NumberJ14.107K
CoE Number10514

Regulatory

FEMA Number3471
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)6790-58-5 ; 1,5,5,9-TETRAMETHYL-13-OXATRICYCLO(8.3.0.0(4,9))TRIDECANE

Physical Properties

Appearance white crystals (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 74.00 to 75.00 °C. @ 760.00 mm Hg, 73.00 to 74.00 °C. @ 760.00 mm Hg
Boiling Point 120.00 to 121.00 °C. @ 1.40 mm Hg
Vapor Pressure 0.009000 mmHg @ 25.00 °C. (est)
Flash Point 322.00 °F. TCC ( 161.11 °C. )
logP (o/w) 5.411 (est)
Shelf Life 48.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Stability antiperspirant spray, good
Similar Items note

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength high ,
Substantivity > 400 hour(s) at 10.00 % in dipropylene glycol
Odor Description
at 1.00 % in dipropylene glycol.
Woody, pine, cedar-like with a green seedy and tea-like nuance
Ambery, Woody, Tobacco, Dry
extremely powerful and elegant amber note with exceptional substantivity, typical ambergris note
strongly amber, woody and dry notes
Amber/ Ambery, Animalic/ Animal, Earthy, Musk/ Musky, Sweet, Woody
Woody, Pine, Cedar, Green Seed, Tea
Extremely powerful and elegant amber odor with a musky, woody tonality
Amber, Ambergris
Strong woody amber, sweet earthy, musky odor with a delicate animalic tonality
Strong woody amber, sweet earthy, musky odor with a delicate animalic tonality
natural whale amber. Sweet, with shades of wood and old paper. Has a long diffusion. Ambreous naphthofuran
Odor sample from Henkel Corporation
Taste Description
at 30.00 ppm in propylene glycol.
woody, cedar wood, floral, leather-like, slightly tobacco note and dry musk-like aftertaste
balsamic amber-like, woody and fresh with a piney and nutty notes

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-mouse LD50 > 3100 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for ambroxan usage levels up to1.0000 % in the fragrance concentrate.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

ACS International GmbH

Creativity Beyond Chemistry

Production • Distribution • Sourcing • Logistics • Consulting

View All Website +49 (0) 55 31 - 99 06-0 info@acsint.com

Advanced Biotech. Inc.

Inspired by Nature

A diverse range of products, all meeting our stringent commitment to quality.

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Associate Allied Chemicals

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Augustus Oils Ltd

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Berje Inc.

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Firmenich Inc.

We Create

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View All Website +34 93 506 91 00 info@indukern.es

Jiangyin Healthway International Trade Co., Ltd

Independent Ingredients Supplier

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View All Website 86-510-86023169 info@healthwaychem.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

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M&U International LLC

Steady supply & demand

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Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

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O'Laughlin Industries Inc.

Manufacturer of chemicals and ingredients used in flavors, fragrances, food, beverages and cosmetics

Leading the Flavor and Fragrance Industry since 1980.

View All Website (973) 376-4600 olcorphk@hkstar.com

OQEMA

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Pell Wall Perfumes

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Prodasynth

PRODUCTEUR PAR ESSENCE

Chemical specialist in manufacturing, distributing and sourcing of tailor-made ingredients for the Flavour & Fragrance industry.

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Sigma-Aldrich

Complete Supply Chain

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SRS Aromatics Ltd

For over 25 years

Bringing flavour and fragrance into your world.

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Sunaux International

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Symrise AG

Always Insiring More

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Supplying Asia Pacific

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The John D. Walsh Company, Inc

Suppliers Since 1942

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The Lermond Company

Your Sourcing Resource

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Tianjin Danjun International Trade Co., LTD.

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Ernesto Ventós S.A.

Leaders in essence

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Vigon International

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

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Potential Uses

FR agate FR amber FR ambergris FR ambreine FR ambrette oil replacer FR animal azzaro FR baby powder FR balsam FR bay rum FR bayberry FR blue grass FR bouquet FR cabreuva wood FR castoreum FR cedar forest FR christmas FR cigar FR clean linen cool water FR coronilla FR deertongue absolute replacer dry FR earth fantasy blends FR fern FR fir balsam FR floral FL/FR guaiacwood FR habuba FR hay new mown hay FR heather FR herbal FR hollyberry FR incense FR juniper berry FR labdanum FR leather FR leather russian leather FR maja FR moss FR musk FR ocean sea FR oriental FR patchouli FR pine forest FR powder FR rain FR sandalwood FR sea breeze FR spice FR spring rain FR sweet grass FR tobacco FR tonka bean tweed FR vanilla FR woodruff FR woody

Natural Occurrence

ambergris PMC

Synonyms

amber ether (A.C.S. International) ambermor (IFF) ambermor-ex (IFF) ambermox amberol synthetic (Advanced Biotech) amberxan ambrofix (Givaudan) ambronica ambrox super (Firmenich) ambroxan ambroxene ambroxide (-)- ambroxide ambroxide cryst. (Symrise) 8alpha-12-oxi do-13,14,15,16-tetranorlabdane (3aR- (3aalpha,5abeta, 9aalpha,9bbeta))- dodecahydro-3a,6,6,9a-tetramethyl naphtho(2,1-b)furan (-)- dodecahydrotetramethyl naphthofuran l'ambroxine lanbroxyde naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)- orcanox superamber 1,5,5,9- tetramethyl-13-oxatricyclo[8.3.0.04,9]tridecane (3aR,5aS,9aS,9bR)-3a,6,6,9a- tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran Google Patents: Biocatalytic Production of Ambroxan US Patents: 8,222,200 - Organic compounds PubMed: Brain responses to odor mixtures with sub-threshold components. US Patents: 8,933,253 - 2-(Alkoxy or aryloxy carbonyl)-4-methyl-6-(2,6,6-trimethylcyclohex-1-enyl)hex-2-enoic acid compunds, its preparation and use PubMed: Purification, partial characterization and substrate specificity of a squalene cyclase from Bacillus acidocaldarius.