amorphousaescin

CAS: 6805-41-0 C54 H84 O23 MW: 1101.24508000

Identification

Nameescin
CAS Number6805-41-0
EINECS229-880-6
FDA UNIIRUU8G67GQM
Molecular FormulaC54 H84 O23
Molecular Weight1101.24508000
MDL NumberMFCD00076054

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usestonic

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-mouse LD50 6700 ug/kg
Dermal Toxicitysubcutaneous-mouse LD50 38590 ug/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA\nKIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"\nLIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"']

Safety in Use

Categorytonic agents
Recommendation for escin usage levels up tonot for fragrance use.
Recommendation for escin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

chestnut horse-chestnut seed

Synonyms

aescin amorphous aescin aescusan escina PubMed: Escin Suppresses Migration and Invasion Involving the Alteration of CXCL16/CXCR6 Axis in Human Gastric Adenocarcinoma AGS Cells. PubMed: Escin attenuates behavioral impairments, oxidative stress and inflammation in a chronic MPTP/probenecid mouse model of Parkinson׳s disease. PubMed: Anti-inflammatory effects of 27 selected terpenoid compounds tested through modulating Th1/Th2 cytokine secretion profiles using murine primary splenocytes. PubMed: Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata BLUME (Hippocastanaceae). PubMed: Identification of novel saponins from edible seeds of Japanese horse chestnut (Aesculus turbinata Blume) after treatment with wooden ashes and their nutraceutical activity. PubMed: Bioavailability of escin after administration of two oral formulations containing aesculus extract.