glyceryl thioglycolate
mercaptoacetic acid, monoester with 1,2,3-propanetriol
Identification
| Name | glyceryl thioglycolate |
| CAS Number | 30618-84-9 |
| EINECS | 250-264-8 |
| FDA UNII | 0FWE72AF2P |
| Molecular Formula | C5 H10 O4 S |
| Molecular Weight | 166.19650000 |
| MDL Number | MFCD00153007 |
| Nikkaji Number | J1.237.846G |
| XlogP3 | -0.70 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 351.28 °C. @ 760.00 mm Hg (est) |
| Flash Point | 331.00 °F. TCC ( 166.30 °C. ) (est) |
| logP (o/w) | -0.799 (est) |
| Soluble in | water, 8.222e+005 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | hair straightening agents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for glyceryl thioglycolate usage levels up to | not for fragrance use. |
| Recommendation for glyceryl thioglycolate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
acetic acid, 2-mercapto-, 2,3-dihydroxypropyl ester
acetic acid, mercapto-, monoester with 1,2,3-propanetriol
acetic acid, mercapto-, monoester with glycerol
2,3-
dihydroxypropyl 2-sulfanylacetate
2,3-
dihydroxypropyl sulfanylacetate
glyceryl monothioglycolate
mercaptoacetic acid, monoester with 1,2,3-propanetriol
mercaptoacetic acid, monoester with propane-1,2,3-triol
PubMed:
North American Contact Dermatitis Group patch test results: 2009 to 2010.
PubMed:
Occupational contact dermatitis in hairdressers/cosmetologists: retrospective analysis of north american contact dermatitis group data, 1994 to 2010.
PubMed:
Occupational contact allergens: are they also associated with occupational asthma?
PubMed:
Final amended report on the safety assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid.
PubMed:
Permanent-wave dermatitis: contact allergy to cysteamine hydrochloride.
PubMed:
Type I and type IV immune responses to glyceryl thioglycolate.
PubMed:
Dermatitis in hairdressers. (I). The experience of the past 4 years.
PubMed:
[Glycerol monothioglycolate eczema in a hairdresser. Persistence of the allergen in the hair several weeks after the application of a permanent].
PubMed:
The patch test dilution of glyceryl thioglycolate.