clotrimazole

diphenyl-(2-chlorophenyl)-1-imidazolylmethane

CAS: 23593-75-1 C22 H17 Cl N2 MW: 344.84349000

Identification

Nameclotrimazole
IUPAC1-[(2-chlorophenyl)-diphenylmethyl]imidazole
CAS Number23593-75-1
FDA UNIIG07GZ97H65
Molecular FormulaC22 H17 Cl N2
Molecular Weight344.84349000
MDL NumberMFCD00057220
Nikkaji NumberJ3.156I
Beilstein0622318

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 148.00 °C. @ 760.00 mm Hg
Soluble in water, 0.02984 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantidandruff agents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-cat LD50 > 1000 mg/kg
Dermal Toxicitysubcutaneous-mouse LDLo 10000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryantidandruff, antimicrobial agents
Recommendation for clotrimazole usage levels up tonot for fragrance use.
Recommendation for clotrimazole flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

bay 5097 bay-B 5097 canesten canestene canifug 1-(o- chloro-alpha,alpha-diphenylbenzyl)imidazole 1-((o- chloro-phenyl)diphenylmethyl)imidazole 1-[(2- chlorophenyl)-diphenylmethyl]imidazole 1-(alpha-(2- chlorophenyl)benzhydryl)imidazole (2- chlorophenyl)diphenyl-1-imidazolylmethane 1-((2- chlorophenyl)diphenylmethyl)-1H-imidazole 1-((2- chlorophenyl)diphenylmethyl)-1H-imidazole (9CI) 1-(o- chlorophenyldiphenylmethyl)imidazole chlorotrityl)imidazole 1-(o- chlorotrityl)imidazole clomatin clotrimazolum cutistad desamix F diphenyl-(2-chlorophenyl)-1-imidazolylmethane diphenyl(2-chlorophenyl)(1-imidazolyl)methane empecid bis- fenil-(2-clorofenil)-1-imidazolil-metano gino-lotremine gyne lotrimin gyne-lotrimin gyne-lotrimin 3 gyne-lotrimin 3 combination pack gyne-lotrimin combination pack gynix 1H- imidazole, 1-((2-chlorophenyl)diphenylmethyl)- imidazole, 1-(o-chloro-alpha,alpha-diphenylbenzyl)- jidesheng lotrimax lotrimin AF lotrisone methane, bis-phenyl-(2-chlorophenyl)-1-imidazolyl- mono-baycuten monobaycuten mycelex 7 mycelex G mycelex OTC mycelex troches mycelex-7 mycelex-7 combination pack mycelex-G mycofug mycosporin mykosporin nalbix pan-fungex pedisafe bis- phenyl-(2-chlorophenyl)(1-imidazoyl)methane bis phenyl-(2-chlorphenyl)-1-imidazolyl-methan bis phenyl-(2-chlorphenyl)-1-imidazolyl-methan [German] rimazole stiemazol tibatin trimysten trivagizole 3 veltrim PubMed: Lauric acid in crown daisy root exudate potently regulates root-knot nematode chemotaxis and disrupts Mi-flp-18 expression to block infection. 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