terephthalylidene dicamphor sulfonic acid

bicyclo(2.2.1)heptane-1-methanesulfonic acid, 3,3'-(1,4-phenylenedimethylidyne)bis(7,7-dimethyl-2-oxo-

CAS: 90457-82-2 C28 H34 O8 S2 MW: 562.70258000

Identification

Nameterephthalylidene dicamphor sulfonic acid
CAS Number90457-82-2
FDA UNIIM94R1PM439
Molecular FormulaC28 H34 O8 S2
Molecular Weight562.70258000
Beilstein8371688

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.1507 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesuv absorbers

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic UV absorber
Recommendation for terephthalylidene dicamphor sulfonic acid usage levels up tonot for fragrance use.
Recommendation for terephthalylidene dicamphor sulfonic acid flavor usage levels up tonot for flavor use.

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Potential Uses

u.v. absorbers

Natural Occurrence

not found in nature

Synonyms

bicyclo(2.2.1)heptane-1-methanesulfonic acid, 3,3'-(1,4-phenylenedimethylidyne)bis(7,7-dimethyl-2-oxo- bicyclo(2.2.1)heptane-1-methanesulfonic acid, 3,3'-(1,4-phenylenedimethylidyne)bis(7,7-dimethyl-2-oxo-, (1S-(1alpha(1R*,4R*),4beta))- [(2E)-2-[[4-[(Z)-[7,7- dimethyl-3-oxo-4-(sulfomethyl)-2-bicyclo[2.2.1]heptanylidene]methyl]phenyl]methylidene]-7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl]methanesulfonic acid ecamsule ecamsule [USAN:USP:INN] mexoryl SX (+-)-(3E,3'E)-(p- phenylenedimethylidyne)bis(2-oxo-10-bornanesulfonic acid) (+-)-(3E,3'E)-3,3'-(p- phenylenedimethylidyne)bis(2-oxo-10-bornanesulfonic acid) 3,3'-(1,4- phenylenedimethylidyne)bis(7,7-dimethyl-2-oxobicyclo(2.2.1)heptane-1-methanesulfonic acid) PubMed: New combination of ultraviolet absorbers in an oily emollient increases sunscreen efficacy and photostability. PubMed: Simultaneous analysis and monitoring of 16 UV filters in cosmetics by high-performance liquid chromatography. PubMed: True photoallergy to sunscreens is rare despite popular belief. PubMed: A new ecamsule-containing SPF 40 sunscreen cream for the prevention of polymorphous light eruption: a double-blind, randomized, controlled study in maximized outdoor conditions. PubMed: Sunscreens containing the broad-spectrum UVA absorber, Mexoryl SX, prevent the cutaneous detrimental effects of UV exposure: a review of clinical study results. PubMed: Rationale for sunscreen development. PubMed: A reversed-phase ion-interaction chromatographic method for in-vitro estimation of the percutaneous absorption of water-soluble UV filters. PubMed: Improvement of the experimental setup for skin absorption screening studies with reconstructed skin EPISKIN. PubMed: OTC product: Anthelios SX. PubMed: Mexoryl: a review of an ultraviolet a filter. PubMed: A new sunscreen agent. PubMed: I've heard there's a new sunscreen that's supposed to offer better skin protection. Can you tell me more? PubMed: The FDA approves new over-the-counter sunscreen. PubMed: Prevention of ultraviolet-induced skin pigmentation. PubMed: Percutaneous absorption of Mexoryl SX in human volunteers: comparison with in vitro data. PubMed: Determination of water-soluble UV-filters in sunscreen sprays by liquid chromatography. PubMed: UVA protection efficacy of sunscreens can be determined by the persistent pigment darkening (PPD) method. (Part 2). PubMed: A full-UV spectrum absorbing daily use cream protects human skin against biological changes occurring in photoaging. PubMed: Protection by ultraviolet A and B sunscreens against in situ dipyrimidine photolesions in human epidermis is comparable to protection against sunburn. PubMed: Evaluation of the protective effect of sunscreens on in vitro reconstructed human skin exposed to UVB or UVA irradiation. PubMed: Comparison of the ability of 2 sunscreens to protect against polymorphous light eruption induced by a UV-A/UV-B metal halide lamp. PubMed: Mexoryl SX: a broad absorption UVA filter protects human skin from the effects of repeated suberythemal doses of UVA. PubMed: An in vitro strategy to evaluate the phototoxicity of solar UV at the molecular and cellular level: application to photoprotection assessment. PubMed: Mexoryl SX protects against solar-simulated UVR-induced photocarcinogenesis in mice. PubMed: Cumulative effects of UVA in human skin. PubMed: Sunscreens with broad-spectrum absorption decrease the trans to cis photoisomerization of urocanic acid in the human stratum corneum after multiple UV light exposures. PubMed: In vivo evaluation of photoprotection against chronic ultraviolet-A irradiation by a new sunscreen Mexoryl SX.