terephthalylidene dicamphor sulfonic acid
bicyclo(2.2.1)heptane-1-methanesulfonic acid, 3,3'-(1,4-phenylenedimethylidyne)bis(7,7-dimethyl-2-oxo-
Identification
| Name | terephthalylidene dicamphor sulfonic acid |
| CAS Number | 90457-82-2 |
| FDA UNII | M94R1PM439 |
| Molecular Formula | C28 H34 O8 S2 |
| Molecular Weight | 562.70258000 |
| Beilstein | 8371688 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.1507 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | uv absorbers |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic UV absorber |
| Recommendation for terephthalylidene dicamphor sulfonic acid usage levels up to | not for fragrance use. |
| Recommendation for terephthalylidene dicamphor sulfonic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
bicyclo(2.2.1)heptane-1-methanesulfonic acid, 3,3'-(1,4-phenylenedimethylidyne)bis(7,7-dimethyl-2-oxo-
bicyclo(2.2.1)heptane-1-methanesulfonic acid, 3,3'-(1,4-phenylenedimethylidyne)bis(7,7-dimethyl-2-oxo-, (1S-(1alpha(1R*,4R*),4beta))-
[(2E)-2-[[4-[(Z)-[7,7-
dimethyl-3-oxo-4-(sulfomethyl)-2-bicyclo[2.2.1]heptanylidene]methyl]phenyl]methylidene]-7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl]methanesulfonic acid
ecamsule
ecamsule [USAN:USP:INN]
mexoryl SX
(+-)-(3E,3'E)-(p-
phenylenedimethylidyne)bis(2-oxo-10-bornanesulfonic acid)
(+-)-(3E,3'E)-3,3'-(p-
phenylenedimethylidyne)bis(2-oxo-10-bornanesulfonic acid)
3,3'-(1,4-
phenylenedimethylidyne)bis(7,7-dimethyl-2-oxobicyclo(2.2.1)heptane-1-methanesulfonic acid)
PubMed:
New combination of ultraviolet absorbers in an oily emollient increases sunscreen efficacy and photostability.
PubMed:
Simultaneous analysis and monitoring of 16 UV filters in cosmetics by high-performance liquid chromatography.
PubMed:
True photoallergy to sunscreens is rare despite popular belief.
PubMed:
A new ecamsule-containing SPF 40 sunscreen cream for the prevention of polymorphous light eruption: a double-blind, randomized, controlled study in maximized outdoor conditions.
PubMed:
Sunscreens containing the broad-spectrum UVA absorber, Mexoryl SX, prevent the cutaneous detrimental effects of UV exposure: a review of clinical study results.
PubMed:
Rationale for sunscreen development.
PubMed:
A reversed-phase ion-interaction chromatographic method for in-vitro estimation of the percutaneous absorption of water-soluble UV filters.
PubMed:
Improvement of the experimental setup for skin absorption screening studies with reconstructed skin EPISKIN.
PubMed:
OTC product: Anthelios SX.
PubMed:
Mexoryl: a review of an ultraviolet a filter.
PubMed:
A new sunscreen agent.
PubMed:
I've heard there's a new sunscreen that's supposed to offer better skin protection. Can you tell me more?
PubMed:
The FDA approves new over-the-counter sunscreen.
PubMed:
Prevention of ultraviolet-induced skin pigmentation.
PubMed:
Percutaneous absorption of Mexoryl SX in human volunteers: comparison with in vitro data.
PubMed:
Determination of water-soluble UV-filters in sunscreen sprays by liquid chromatography.
PubMed:
UVA protection efficacy of sunscreens can be determined by the persistent pigment darkening (PPD) method. (Part 2).
PubMed:
A full-UV spectrum absorbing daily use cream protects human skin against biological changes occurring in photoaging.
PubMed:
Protection by ultraviolet A and B sunscreens against in situ dipyrimidine photolesions in human epidermis is comparable to protection against sunburn.
PubMed:
Evaluation of the protective effect of sunscreens on in vitro reconstructed human skin exposed to UVB or UVA irradiation.
PubMed:
Comparison of the ability of 2 sunscreens to protect against polymorphous light eruption induced by a UV-A/UV-B metal halide lamp.
PubMed:
Mexoryl SX: a broad absorption UVA filter protects human skin from the effects of repeated suberythemal doses of UVA.
PubMed:
An in vitro strategy to evaluate the phototoxicity of solar UV at the molecular and cellular level: application to photoprotection assessment.
PubMed:
Mexoryl SX protects against solar-simulated UVR-induced photocarcinogenesis in mice.
PubMed:
Cumulative effects of UVA in human skin.
PubMed:
Sunscreens with broad-spectrum absorption decrease the trans to cis photoisomerization of urocanic acid in the human stratum corneum after multiple UV light exposures.
PubMed:
In vivo evaluation of photoprotection against chronic ultraviolet-A irradiation by a new sunscreen Mexoryl SX.