croton oil

croton tiglium oil

CAS: 8001-28-3

Identification

Namecroton oil
IUPACcroton tiglium oil
CAS Number8001-28-3
FDA UNIIWK97EQG57S

Regulatory

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Food Chemicals Codex Listed No
Soluble in alcohol
Insoluble in water

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-frog LD50 60 mg/kg
Dermal Toxicitysubcutaneous-mouse LD70 3740 ug/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for croton oil usage levels up tonot for fragrance use.
Recommendation for croton oil flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

croton tiglium

Synonyms

croton tiglium oil PubMed: Anticonvulsant effect of hydroalcoholic seed extract of croton tiglium in rats and mice. PubMed: Cytotoxic phorbol esters of Croton tiglium. PubMed: [GC-MS analysis of chemical components in seeds oil from Croton tiglium]. PubMed: [New processing procedure for Croton tiglium with study on comparison of Croton tiglium and processed product]. PubMed: Antinociceptive and Smooth Muscle Relaxant Activity of Croton tiglium L Seed: An In-vitro and In-vivo Study. PubMed: Activation of M3 muscarinic receptor and Ca²⁺ influx by crude fraction from Crotonis Fructus in isolated rabbit jejunum. PubMed: Anti-tumor activity of Aloe vera against DMBA/croton oil-induced skin papillomagenesis in Swiss albino mice. PubMed: Toxic effects of crotocaudin extracted from the medicinal plant Croton tiglium. PubMed: M3 muscarinic receptor- and Ca2+ influx-mediated muscle contractions induced by croton oil in isolated rabbit jejunum. PubMed: Activity-guided isolation of a novel protein from Croton tiglium with antifungal and antibacterial activities. PubMed: Characteristics, efficacy and safety testing of standardized extract of Croton tiglium seed from Indonesia as laxative material. PubMed: Effects of essential oil from Croton tiglium L. on intestinal transit in mice. PubMed: A novel analgesic pyrazine derivative from the leaves of Croton tiglium L. PubMed: A DNA microarray for the authentication of toxic traditional Chinese medicinal plants. PubMed: [Inhibitory effects of some traditional medicines on proliferation of HIV-1 and its protease]. PubMed: Effect of ethanol extracts of three Chinese medicinal plants with laxative properties on ion transport of the rat intestinal epithelia. PubMed: Protein kinase C translocation by modified phorbol esters with functionalized lipophilic regions. PubMed: Biotransformation of phorbol by human intestinal bacteria. PubMed: Anti-HIV-1 phorbol esters from the seeds of Croton tiglium. PubMed: Ethnomedicinally selected plants as sources of potential analgesic compounds: indication of in vitro biological activity in receptor binding assays. PubMed: 12-O-acetylphorbol-13-decanoate potently inhibits cytopathic effects of human immunodeficiency virus type 1 (HIV-1), without activation of protein kinase C. PubMed: Gastro intestinal effects of croton tiglium in experimental animals. PubMed: Sensitivity of ribosomes from Agrobacterium tumefaciens to the ribosome-inactivating protein crotin 2 depending on the translocational state. PubMed: Isolation of isoguanosine from Croton tiglium and its antitumor activity. PubMed: Screening of Epstein-Barr virus early antigen expression inducers from Chinese medicinal herbs and plants. PubMed: Preliminary crystallographic studies of crotin II. PubMed: Effects of ribosome-inactivating proteins on Escherichia coli and Agrobacterium tumefaciens translation systems. PubMed: Preparation, optimization and characterization of a polyphenylalanine synthetizing system from Agrobacterium tumefaciens. PubMed: Enterolobin, a hemolytic protein from Enterolobium contortisiliquum seeds (Leguminosae--Mimosoideae). Purification and characterization. PubMed: A Method for Quantitative Determination of Polyfunctional Diterpene Esters of the Tigliane Type in Croton tiglium. PubMed: [Historical studies on the processing of the fruits of Croton tiglium L.)]. PubMed: Purification and properties of a lectin from the seeds of Croton tiglium with hemolytic activity toward rabbit red cells. PubMed: Combined effect of the extracts from Croton tiglium, Euphorbia lathyris or Euphorbia tirucalli and n-butyrate on Epstein-Barr virus expression in human lymphoblastoid P3HR-1 and Raji cells. PubMed: alpha-Tocopherol inhibits 12-O-tetradecanoyl-phorbol-13-acetate-stimulated deacylation of cellular lipids, prostaglandin production, and changes in cell morphology of Madin-Darby canine kidney cells. PubMed: Studies on the proteins from the seeds of Croton tiglium and of Jatropha curcas. Toxic properties and inhibition of protein synthesis in vitro. PubMed: Antileukemic principles isolated from euphorbiaceae plants. PubMed: Phorbolesters--the irritants and cocarcinogens of Croton Tiglium L. PubMed: Cocarcinogenic principles from the seed oil of Croton tiglium and from other Euphorbiaceae. PubMed: Tumor-promoting agents from Croton tiglium L. and their mode of action. PubMed: Phenotypic expression of transformation: induction in cell culture by a phorbol ester. PubMed: The tumor-enhancing principles of Croton tiglium L. II. A comparative study. PubMed: The tumor-enhancing principles of Croton tiglium L. PubMed: TUMOUR-ENHANCING ACTIVITY OF THE ACTIVE PRINCIPLES OF CROTON TIGLIUM L. PubMed: THE TUMOR-ENHANCING AND IRRITANT PRINCIPLES FROM CROTON TIGLIUM L. PubMed: [Croton tiglium powder as an auxiliary treatment in laryngeal obstruction due to diphtheria or laryngitis: preliminary report of 116 cases]. PubMed: Tumor promoting principles in seeds of Croton tiglium L. PubMed: On a New Preparation of Croton Tiglium.