erythritol
tetritol
Identification
| Name | erythritol |
| CAS Number | 7541-59-5 |
| EINECS | 231-418-3 |
| FDA UNII | Search |
| Molecular Formula | C4 H10 O4 |
| Molecular Weight | 122.12050000 |
| Nikkaji Number | J307.870A |
| XlogP3 | -2.30 (est) |
Regulatory
| DG SANTE Food Additives | erythritol |
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | humectants |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | humectants |
| Recommendation for erythritol usage levels up to | not for fragrance use. |
| Recommendation for erythritol flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
butane-1,2,3,4-tetrol
tetritol
PubMed:
A two-stage fermentation process of erythritol production by yeast Y. lipolytica from molasses and glycerol.
PubMed:
Redirection of metabolite biosynthesis from hydroxybenzoates to volatile terpenoids in green hairy roots of Daucus carota.
PubMed:
Concomitant osmotic and chaotropicity-induced stresses in Aspergillus wentii: compatible solutes determine the biotic window.
PubMed:
Dietary intake of sugar substitutes aggravates cerebral ischemic injury and impairs endothelial progenitor cells in mice.
PubMed:
Role of FODMAPs in Patients With Irritable Bowel Syndrome.
PubMed:
Natural variation in monoterpene synthesis in kiwifruit: transcriptional regulation of terpene synthases by NAC and ETHYLENE-INSENSITIVE3-like transcription factors.
PubMed:
Biosynthesis of β-carotene in engineered E. coli using the MEP and MVA pathways.
PubMed:
Cloning of the transketolase gene from erythritol-producing yeast Candida magnoliae.
PubMed:
Optimization of medium composition for erythritol production from glycerol by Yarrowia lipolytica using response surface methodology.
PubMed:
Does Plasmodium falciparum have an Achilles' heel?
PubMed:
[Simultaneous determination of sugar alcohols and sugars in functional foods by precolumn ultraviolet derivatization--high performance liquid chromatography].
PubMed:
Sweetness and other sensory properties of model fruit drinks: Does viscosity have an impact?
PubMed:
Bacillus invictae sp. nov., isolated from a health product.
PubMed:
Evaluation of coriander spice as a functional food by using in vitro bioassays.
PubMed:
Two transaldolase isogenes from Moniliella megachiliensis behave in a different way depending on the stress class.
PubMed:
A comparative study on glycerol metabolism to erythritol and citric acid in Yarrowia lipolytica yeast cells.
PubMed:
Erythritol, a non-nutritive sugar alcohol sweetener and the main component of truvia®, is a palatable ingested insecticide.
PubMed:
Alditols and monosaccharides from sorghum vinegar can attenuate platelet aggregation by inhibiting cyclooxygenase-1 and thromboxane-A2 synthase.
PubMed:
Engineering the lactococcal mevalonate pathway for increased sesquiterpene production.
PubMed:
Hypocholesterolemic activity of monascus fermented product in the absence of monacolins with partial purification for functional food applications.
PubMed:
Use of just-about-right scales and penalty analysis to determine appropriate concentrations of stevia sweeteners for vanilla yogurt.
PubMed:
Recognition of riboflavin and the capsular polysaccharide of Haemophilus influenzae type b by antibodies generated to the haptenic epitope D-ribitol.
PubMed:
Methylerythritol and mevalonate pathway contributions to biosynthesis of mono-, sesqui-, and diterpenes in glandular trichomes and leaves of Stevia rebaudiana Bertoni.
PubMed:
[Determination of alditols in foods by ion chromatography-mass spectrometry].
PubMed:
[Case of 5 year-old boy with anaphylaxis due to erythritol with negative prick test and positive intradermal test].
PubMed:
Mineral supplementation increases erythrose reductase activity in erythritol biosynthesis from glycerol by Yarrowia lipolytica.
PubMed:
Detection of sugar alcohol-specific IgE.
PubMed:
[Simultaneous determination of monosaccharides, disaccharides, oligosaccharides and sugar alcohols in foods by high performance liquid chromatography with evaporative light-scattering detection].
PubMed:
[Determination of alditols in wine by gas chromatography-mass spectrometry after acetate derivatization].
PubMed:
Enhanced production of erythritol by Yarrowia lipolytica on glycerol in repeated batch cultures.
PubMed:
Selective production of two diastereomers of disaccharide sugar alcohol, mannosylerythritol by Pseudozyma yeasts.
PubMed:
Microbiological Characteristics of Wild Yeast Strain Pichia anomala Y197-13 for Brewing Makgeolli.
PubMed:
[Method of quantitative analysis by HPLC and confirmation by LC-MS of sugar alcohols in foods].
PubMed:
Biosynthesis of sesquiterpenes in grape berry exocarp of Vitis vinifera L.: evidence for a transport of farnesyl diphosphate precursors from plastids to the cytosol.
PubMed:
Investigation of protein expression profiles of erythritol-producing Candida magnoliae in response to glucose perturbation.
PubMed:
Aqueous and hydro-alcoholic media effects on polyols.
PubMed:
Beneficial effect of tagatose consumption on postprandial hyperglycemia in Koreans: a double-blind crossover designed study.
PubMed:
Fructose malabsorption syndrome.
PubMed:
"Bitter sweet": a child case of erythritol-induced anaphylaxis.
PubMed:
Pectinatus sottacetonis sp. nov., isolated from a commercial pickle spoilage tank.
PubMed:
Biotechnological and in situ food production of polyols by lactic acid bacteria.
PubMed:
Inulin and erythritol as sucrose replacers in short-dough cookies: sensory, fracture, and acoustic properties.
PubMed:
Overexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene production.
PubMed:
Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum.
PubMed:
Sensory characteristics and relative sweetness of tagatose and other sweeteners.
PubMed:
Novel multi-sugar assay for site-specific gastrointestinal permeability analysis: a randomized controlled crossover trial.
PubMed:
Production of erythritol and mannitol by Yarrowia lipolytica yeast in media containing glycerol.
PubMed:
Functional expression of an orchid fragrance gene in Lactococcus lactis.
PubMed:
Dietary D-psicose reduced visceral fat mass in high-fat diet-induced obese rats.
PubMed:
Novel analytical approach to a multi-sugar whole gut permeability assay.
PubMed:
Sugar alcohol sweeteners as alternatives to sugar with special consideration of xylitol.
PubMed:
Comparison of citric acid production from glycerol and glucose by different strains of Yarrowia lipolytica.
PubMed:
Stevia and saccharin preferences in rats and mice.
PubMed:
Biotechnological production of erythritol and its applications.
PubMed:
Perspectives of engineering lactic acid bacteria for biotechnological polyol production.
PubMed:
Characterization of galactosyl derivatives obtained by transgalactosylation of lactose and different polyols using immobilized beta-galactosidase from Aspergillus oryzae.
PubMed:
High-yield production of erythritol from raw glycerol in fed-batch cultures of Yarrowia lipolytica.
PubMed:
Analysis of erythritol in foods by polyclonal antibody-based indirect competitive ELISA.
PubMed:
[Gene regulation to lactic acid bacteria for increasing production of flavor metabolite].
PubMed:
Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice.
PubMed:
Population dynamics and metabolite target analysis of lactic acid bacteria during laboratory fermentations of wheat and spelt sourdoughs.
PubMed:
Use of the arginine-specific butanedione/phenylboronic acid tag for analysis of peptides and protein digests using matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:
Cryptococcus anemochoreius sp. nov., a novel anamorphic basidiomycetous yeast isolated from the atmosphere in central South Africa.
PubMed:
Generation of an antibody specific to erythritol, a non-immunogenic food additive.
PubMed:
Variations in the energy metabolism of biotechnologically relevant heterofermentative lactic acid bacteria during growth on sugars and organic acids.
PubMed:
Biosynthesis of mono- and sesquiterpenes in strawberry fruits and foliage: 2H labeling studies.
PubMed:
Bacteriostatic activities of monoacyl sugar alcohols against thermophilic sporeformers.
PubMed:
Combination of analyte protectants to overcome matrix effects in routine GC analysis of pesticide residues in food matrixes.
PubMed:
Human gut microbiota does not ferment erythritol.
PubMed:
Production of L-erythrose via L-erythrulose from erythritol using microbial and enzymatic reactions.
PubMed:
Production of L-sorbitol from L-fructose by Aureobasidium pullulans LP23 isolated from soy sauce mash.
PubMed:
Numerical and genetic analysis of polycyclic aromatic hydrocarbon-degrading mycobacteria.
PubMed:
Primary structure analysis and functional expression of erythrose reductases from erythritol-producing fungi (Trichosporonoides megachiliensis SNG-42).
PubMed:
Induction of de novo volatile terpene biosynthesis via cytosolic and plastidial pathways by methyl jasmonate in foliage of Vitis vinifera L.
PubMed:
Substrate utilization by Aspergillus flavus in inoculated whole corn kernels and isolated tissues.
PubMed:
Proteomics and physiology of erythritol-producing strains.
PubMed:
Anaphylaxis to excipient mannitol: evidence for an immunoglobulin E-mediated mechanism.
PubMed:
Physical stability and moisture sorption of aqueous chitosan-amylose starch films plasticized with polyols.
PubMed:
Solid-state and mechanical properties of aqueous chitosan-amylose starch films plasticized with polyols.
PubMed:
Polyol accumulation by Aspergillus oryzae at low water activity in solid-state fermentation.
PubMed:
Antagonistic activity of lactic acid bacteria as probiotics against selected bacteria of the Enterobaceriacae family in the presence of polyols and their galactosyl derivatives.
PubMed:
Alpha-mercaptoketone formation during the maillard reaction of cysteine and [1-(13)C]ribose.
PubMed:
Biogenetic studies in Syringa vulgaris L.: bioconversion of (18)O(2H)-labeled precursors into lilac aldehydes and lilac alcohols.
PubMed:
Health potential of polyols as sugar replacers, with emphasis on low glycaemic properties.
PubMed:
Use of DSC to detect the heterogeneity of hydrothermal stability in the polyphenol-treated collagen matrix.
PubMed:
Odorants in breast milk.
PubMed:
The methylerythritol phosphate pathway and its significance as a novel drug target.
PubMed:
Biosynthesis of anthecotuloide, an irregular sesquiterpene lactone from Anthemis cotula L. (Asteraceae) via a non-farnesyl diphosphate route.
PubMed:
Maltosyl-erythritol, a major transglycosylation product of erythritol by Bacillus stearothermophilus maltogenic amylase.
PubMed:
Biogenetic studies in Syringa vulgaris L.: synthesis and bioconversion of deuterium-labeled precursors into lilac aldehydes and lilac alcohols.
PubMed:
Erythritol attenuates the diabetic oxidative stress through modulating glucose metabolism and lipid peroxidation in streptozotocin-induced diabetic rats.
PubMed:
Time course study of substrate utilization by Aspergillus flavus in medium simulating corn (Zea mays) kernels.
PubMed:
Allergic reactions after ingestion of erythritol-containing foods and beverages.
PubMed:
[New food substitute (sweetener)--erythritol].
PubMed:
Evaluation of certain food additives and contaminants.
PubMed:
Determination of sugar alcohols in confectioneries by high-performance liquid chromatography after nitrobenzoylation.
PubMed:
Influence of lipids with and without other cottonseed reserve materials on aflatoxin B(1) production by Aspergillus flavus.
PubMed:
A case of allergic urticaria caused by erythritol.
PubMed:
What clients need to know about sugar replacers.
PubMed:
Erythritol: a novel noncaloric sweetener ingredient.
PubMed:
Liquid chromatographic determination of sugar alcohols in beverages and foods after nitrobenzoylation.
PubMed:
Enzymatic synthesis of edible surfactants from food ingredients.
PubMed:
Erythritol: an interpretive summary of biochemical, metabolic, toxicological and clinical data.
PubMed:
Biochemical characteristics of osmophilic yeasts isolated from pollens and honey.
PubMed:
Effects of oral administration of erythritol on patients with diabetes.
PubMed:
Chronic toxicity and carcinogenicity study of erythritol in rats.
PubMed:
Two-generation reproduction study of erythritol in rats.
PubMed:
Embryotoxicity and teratogenicity study with erythritol in rats.
PubMed:
Subchronic oral toxicity studies with erythritol in mice and rats.
PubMed:
Four-week oral toxicity study with erythritol in rats.
PubMed:
Effect of polyols on heat inactivation of Aspergillus niger van Teighem inulinase.
PubMed:
A novel type of meso-diaminopimelic acid-based peptidoglycan and novel poly(erythritol phosphate) teichoic acids in cell walls of two coryneform isolates from the surface flora of French cooked cheeses.
PubMed:
Intramolecular esterification by lipase powder in microaqueous benzene: factors affecting activity of pure enzyme.
PubMed:
Carbohydrate Storage in the Entomopathogenic Fungus Beauveria bassiana.
PubMed:
[Increasing the effectiveness of the method of Staphylococcus phage-typing].
PubMed:
The effect of feeding on the bile salt-independent canalicular secretion in dogs.