scutellaria baicalensis root

scutellaria lanceolaria root scutellaria macrantha root baikal skullcap root PubMed: The effects of the standardized herbal formula PM014 on pulmonary inflammation and airway responsiveness in a murine model of cockroach allergen-induced asthma. PubMed: Baicalein pretreatment confers cardioprotection against acute myocardial infarction by activating the endothelial nitric oxide synthase signaling pathway and inhibiting oxidative stress. PubMed: Bone marrow microenvironment confers imatinib resistance to chronic myelogenous leukemia and oroxylin A reverses the resistance by suppressing Stat3 pathway. PubMed: Wogonin-enhanced reactive oxygen species-induced apoptosis and potentiated cytotoxic effects of chemotherapeutic agents by suppression Nrf2-mediated signaling in HepG2 cells. PubMed: Oroxylin A inhibits hypoxia-induced invasion and migration of MCF-7 cells by suppressing the Notch pathway. PubMed: [Physiological ecology responses of Scutellaria baicalensis to drought and rewatering]. PubMed: Baicalein, an active component of Scutellaria baicalensis, protects against lipopolysaccharide-induced acute lung injury in rats. PubMed: Synthesis and biological evaluation of baicalein derivatives as potent antitumor agents. PubMed: Baicalin protects PC-12 cells from oxidative stress induced by hydrogen peroxide via anti-apoptotic effects. PubMed: Purification and antioxidant activities of baicalin isolated from the root of huangqin (Scutellaria baicalensis gcorsi). PubMed: Simulated gastrointestinal tract metabolism and pharmacological activities of water extract of Scutellaria baicalensis roots. PubMed: Cloning and characterization of a cDNA encoding calcium/calmodulin-dependent glutamate decarboxylase from Scutellaria baicalensis. PubMed: Probe substrate and enzyme source-dependent inhibition of UDP-glucuronosyltransferase (UGT) 1A9 by wogonin. PubMed: Chronic administration of baicalein decreases depression-like behavior induced by repeated restraint stress in rats. PubMed: Baicalin inhibits Staphylococcus aureus-induced apoptosis by regulating TLR2 and TLR2-related apoptotic factors in the mouse mammary glands. PubMed: [Study on transport mechanism of baicalin in Scutellariae radix extracts and effect of Angelica dahurica extracts on transport of baicalin by Caco-2 cell monolayer model]. PubMed: Wogonin influences vascular permeability via Wnt/β-catenin pathway. PubMed: [Study on rapid propagation of Scutellaria baicalensis variation]. PubMed: Influence of mefenamic acid on the intestinal absorption and metabolism of three bioactive flavones in Radix Scutellariae and potential pharmacological impact. PubMed: Inhibitory effects of baicalin in the early stage of 3T3-L1 preadipocytes differentiation by down-regulation of PDK1/Akt phosphorylation. PubMed: [Study on HPLC-fingerprint-based identification of dao-di herb and non dao-di herb of scutellariae radix]. PubMed: Scutellariae radix suppresses LPS-induced liver endothelial cell activation and inhibits hepatic stellate cell migration. PubMed: Baicalein, an active component of Scutellaria baicalensis Georgi, induces apoptosis in human colon cancer cells and prevents AOM/DSS-induced colon cancer in mice. PubMed: Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury. PubMed: Baicalein selectively induces apoptosis in activated lymphocytes and ameliorates concanavalin a-induced hepatitis in mice. PubMed: Bioconversion of flavones during fermentation in milk containing Scutellaria baicalensis extract by Lactobacillus brevis. PubMed: Assessment of dermal safety of Scutellaria baicalensis aqueous extract topical application on skin hypersensitivity. PubMed: [Effect of different developmental stage on plant growth and active compounds in Scutellaria baicalensis]. PubMed: Wogonin ameliorates hyperglycemia and dyslipidemia via PPARα activation in db/db mice. PubMed: Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells. PubMed: Wogonoside induces cell cycle arrest and differentiation by affecting expression and subcellular localization of PLSCR1 in AML cells. PubMed: Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest. PubMed: [Effects of plant growth regulator mepiquat chloride on content of active compounds in Scutellaria baicalensis]. PubMed: Baicalin regulates neuronal fate decision in neural stem/progenitor cells and stimulates hippocampal neurogenesis in adult rats. PubMed: The potential anticancer activity of extracts derived from the roots of Scutellaria baicalensis on human oral squamous cell carcinoma cells. PubMed: [Effect of Scutellaria baicalensis root extract on cytogenetic damage induced by paclitaxel and cisplatin in mice]. PubMed: Wogonin inhibits H2O2-induced vascular permeability through suppressing the phosphorylation of caveolin-1. PubMed: Baicalein protects against cardiac hypertrophy through blocking MEK-ERK1/2 signaling. PubMed: [Responses of Scutellaria baicalensis Georgi yield and root baicalin content to the fertilization rates of nitrogen, phosphorus, and potassium]. PubMed: Baicalein inhibits DMBA/TPA-induced skin tumorigenesis in mice by modulating proliferation, apoptosis, and inflammation. PubMed: Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathway. PubMed: [Research on relationship between commercial specifications of Scutellariae Radix and chemical composition and drug quality]. PubMed: Wogonin potentiates cisplatin-induced cancer cell apoptosis through accumulation of intracellular reactive oxygen species. PubMed: [Effects of three fungicides on arbuscular mycorrhizal fungal infection and growth of Scutellaria baicalensis Georgi]. PubMed: Drug resistance associates with activation of Nrf2 in MCF-7/DOX cells, and wogonin reverses it by down-regulating Nrf2-mediated cellular defense response. PubMed: Flavonoids and antioxidative enzymes in temperature-challenged roots of Scutellaria baicalensis Georgi. PubMed: Relaxant effect induced by wogonin from Scutellaria baicalensis on rat isolated uterine smooth muscle. PubMed: Baicalin is anti-inflammatory in cigarette smoke-induced inflammatory models in vivo and in vitro: A possible role for HDAC2 activity. PubMed: A simple isocratic HPLC method for the simultaneous determination of bioactive components of Scutellariae radix extract. PubMed: Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism. PubMed: Pharmacokinetic study of baicalein after oral administration in monkeys. PubMed: [Analysis of the content of mineral elements in Scutellaria baicalensis, skullcap tea and its solution]. PubMed: Synthesis and biological evaluation of 7-O-modified oroxylin A derivatives. PubMed: Effect of baikal skullcap root (Scutellaria baicalensis radix) on cholesterol level and meat quality in rabbits fed a cholesterol rich diet. PubMed: [Effects of AM fungi on growth and microelement of Scuteliaria baiealensis under different applied phosphorous levels]. PubMed: [Comparative and correlational studies on contents of flavonoids in axial root and lateral root of Scutellaria baicalensis]. PubMed: Baicalein inhibits oxidative stress-induced cellular damage via antioxidant effects. PubMed: Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones. PubMed: Baicalin reduces the permeability of the blood-brain barrier during hypoxia in vitro by increasing the expression of tight junction proteins in brain microvascular endothelial cells. PubMed: In vitro and in situ evaluation of herb-drug interactions during intestinal metabolism and absorption of baicalein. PubMed: Enhanced bioavailability after oral and pulmonary administration of baicalein nanocrystal. PubMed: Synergistic activity of baicalein with ribavirin against influenza A (H1N1) virus infections in cell culture and in mice. PubMed: Extract of Scutellaria baicalensis Georgi root exerts protection against myocardial ischemia-reperfusion injury in rats. PubMed: Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. PubMed: Enhancement of flavone levels through overexpression of chalcone isomerase in hairy root cultures of Scutellaria baicalensis. PubMed: Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation. PubMed: A novel therapeutic regimen for hepatic fibrosis using the combination of mesenchymal stem cells and baicalin. PubMed: Baicalein and wogonin are activators of rat TREK-2 two-pore domain K+ channel. PubMed: Neuroprotective effect of oral S/B remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) on iron-induced neurodegeneration in the nigrostriatal dopaminergic system of rat brain. PubMed: Effects of baicalein on Sendai virus in vivo are linked to serum baicalin and its inhibition of hemagglutinin-neuraminidase. PubMed: Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? PubMed: Analysis of essential oils from different organs of Scutellaria baicalensis. PubMed: Oroxylin A increases BDNF production by activation of MAPK-CREB pathway in rat primary cortical neuronal culture. PubMed: Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. PubMed: Wogonin induces differentiation and neurite outgrowth of neural precursor cells. PubMed: Baicalin increases VEGF expression and angiogenesis by activating the ERR{alpha}/PGC-1{alpha} pathway. PubMed: Effects of a skullcap root supplement on haematology, serum parameters and antioxidant enzymes in rabbits on a high-cholesterol diet. PubMed: Evaluation of anti-oxidant capacity of root of Scutellaria baicalensis Georgi, in comparison with roots of Polygonum multiflorum Thunb and Panax ginseng CA Meyer. PubMed: Opposite expression of securin and γ-H2AX regulates baicalein-induced cancer cell death. PubMed: Secondary metabolite mapping identifies Scutellaria inhibitors of human lung cancer cells. PubMed: Impacts of recent cultivation on genetic diversity pattern of a medicinal plant, Scutellaria baicalensis (Lamiaceae). PubMed: Anti-nociceptive mechanism of baicalin involved in intervention of TRPV1 in DRG neurons in vitro. PubMed: Molecular cloning and expression profiling of a chalcone synthase gene from hairy root cultures of Scutellaria viscidula Bunge. PubMed: On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi. PubMed: The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis. PubMed: Neuroprotective effect of baicalein on hydrogen peroxide-mediated oxidative stress and mitochondrial dysfunction in PC12 cells. PubMed: Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages. PubMed: MAC-related mitochondrial pathway in oroxylin-A-induced apoptosis in human hepatocellular carcinoma HepG2 cells. PubMed: Wogonoside inhibits lipopolysaccharide-induced angiogenesis in vitro and in vivo via toll-like receptor 4 signal transduction. PubMed: Baicalin administration is effective in positive regulation of twenty-four ischemia/reperfusion-related proteins identified by a proteomic study. PubMed: In vitro antifungal activity of the aqueous extract of Scutellaria baicalensis Georgi root against Candida albicans. PubMed: Anti-diabetic effect of American ginseng may not be linked to antioxidant activity: comparison between American ginseng and Scutellaria baicalensis using an ob/ob mice model. PubMed: Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro. PubMed: In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root. PubMed: [Separation and purification and structural characterization of baicalein]. PubMed: Optimization of capillary liquid chromatography with electrochemical detection for determining femtogram levels of baicalin and baicalein on the basis of the FUMI theory. PubMed: Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity. PubMed: Scutellaria baicalensis enhances the anti-diabetic activity of metformin in streptozotocin-induced diabetic Wistar rats. PubMed: [Determination of the contents of trace elements in chinese herbal medicines for treating respiratory system diseases]. PubMed: Validation of a HPLC method for flavonoid biomarkers in skullcap (Scutellaria) and its use to illustrate wide variability in the quality of commercial tinctures. PubMed: Comparison of the major flavonoid content of S. baicalensis, S. lateriflora, and their commercial products. PubMed: Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression. PubMed: Reduction of urate crystal-induced inflammation by root extracts from traditional oriental medicinal plants: elevation of prostaglandin D2 levels. PubMed: The ameliorating effect of oroxylin A on scopolamine-induced memory impairment in mice. PubMed: Effect of the flavonoid, oroxylin A, on transient cerebral hypoperfusion-induced memory impairment in mice. PubMed: Characterization of flavonoids in the traditional Chinese herbal medicine-Huangqin by liquid chromatography coupled with electrospray ionization mass spectrometry. PubMed: Inhibition of cyclic strain-induced endothelin-1 secretion by baicalein in human umbilical vein endothelial cells. PubMed: Antioxidative and anti-inflammatory activities of polyhydroxyflavonoids of Scutellaria baicalensis GEORGI. PubMed: Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells. PubMed: Differential inhibitory effects of baicalein and baicalin on LPS-induced cyclooxygenase-2 expression through inhibition of C/EBPbeta DNA-binding activity. PubMed: [Analysis of the volatile components of YL2000 decoction by GC-MS]. PubMed: Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. PubMed: [Determination of contents of the effective ingredients in root of Scutellaria baicalensis by HPLC-ECD]. PubMed: Traditional Chinese medicine Bao Gan Ning increase phosphorylation of CREB in liver fibrosis in vivo and in vitro. PubMed: Skullcapflavone I from Scutellaria baicalensis induces apoptosis in activated rat hepatic stellate cells. PubMed: Kinetic difference of baicalin in rat blood and cerebral nuclei after intravenous administration of Scutellariae Radix extract. PubMed: Beneficial effect of flavonoid baicalein in cisplatin-induced cell death of human glioma cells. PubMed: Identification and quantification of eight flavones in root and shoot tissues of the medicinal plant huang-qin (Scutellaria baicalensis Georgi) using high-performance liquid chromatography with diode array and mass spectrometric detection. PubMed: Baicalein protects rat cardiomyocytes from hypoxia/reoxygenation damage via a prooxidant mechanism. PubMed: Pharmacokinetics of baicalin in rats and its interactions with cyclosporin A, quinidine and SKF-525A: a microdialysis study. PubMed: [Experimental study on anti-pyretic effect of gegen qin lian decoction and its compounds]. PubMed: Neuroprotective effect of wogonin: potential roles of inflammatory cytokines. PubMed: Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. PubMed: Baicalein induces apoptosis through ROS-mediated mitochondrial dysfunction pathway in HL-60 cells. PubMed: Flavonoids from Radix Scutellariae as potential stroke therapeutic agents by targeting the second postsynaptic density 95 (PSD-95)/disc large/zonula occludens-1 (PDZ) domain of PSD-95. PubMed: Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats. PubMed: Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis georgi. PubMed: [The study of characteristics of absorption and separation of different glycoside on macropore resins]. PubMed: Significant decrease of cyclosporine bioavailability in rats caused by a decoction of the roots of Scutellaria baicalensis. PubMed: Involvement of nuclear factor-kappaB in the inhibition of interleukin-12 production from mouse macrophages by baicalein, a flavonoid in Scutellaria baicalensis. PubMed: Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. PubMed: Main flavonoids in the root of Scutellaria baicalensis cultivated in Europe and their comparative antiradical properties. PubMed: [A novel approach to quality evaluation of root of Scutellaria baicalensis by DPPH free radical scavenging]. PubMed: Flavonoid baicalein attenuates activation-induced cell death of brain microglia. PubMed: Baicalin promoted the repair of DNA single strand breakage caused by H2O2 in cultured NIH3T3 fibroblasts. PubMed: The effects of the cyclosporin A, a P-glycoprotein inhibitor, on the pharmacokinetics of baicalein in the rat: a microdialysis study. PubMed: Baikal skullcap extract stimulates neurite growth in cultures of rat dorsal root Ganglia. PubMed: Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi. PubMed: Scutellaria baicalensis inhibits liver fibrosis induced by bile duct ligation or carbon tetrachloride in rats. PubMed: Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice. PubMed: [A histochemical study on baicalin]. PubMed: Baicalein induces a dual growth arrest by modulating multiple cell cycle regulatory molecules. PubMed: The plant flavonoid wogonin suppresses death of activated C6 rat glial cells by inhibiting nitric oxide production. PubMed: Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes. PubMed: Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. PubMed: Cloning and expression of UDP-glucose: flavonoid 7-O-glucosyltransferase from hairy root cultures of Scutellaria baicalensis. PubMed: Baicalein: an in vitro antigenotoxic compound from Scutellaria baicalensis. PubMed: Extract from Scutellaria baicalensis Georgi attenuates oxidant stress in cardiomyocytes. PubMed: Inhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages. PubMed: Effects of Sho-saiko-to, San'o-shashin-to and Scutellariae Radix on intracellular Ca2+ mobilization in C6 rat glioma cells. PubMed: Baicalin and baicalein, constituents of an important medicinal plant, inhibit intracellular Ca2+ elevation by reducing phospholipase C activity in C6 rat glioma cells. PubMed: Benzodiazepine binding site-interactive flavones from Scutellaria baicalensis root. PubMed: Pharmacological effects of methanolic extract from the root of Scutellaria baicalensis and its flavonoids on human gingival fibroblast. PubMed: [Antifungal activity in vitro of Scutellaria baicalensis Georgi upon cutaneous and ungual pathogenic fungi]. PubMed: Studies on inhibitors of skin tumor promotion. XI. Inhibitory effects of flavonoids from Scutellaria baicalensis on Epstein-Barr virus activation and their anti-tumor-promoting activities. PubMed: Inhibition of influenza virus sialidase and anti-influenza virus activity by plant flavonoids. PubMed: [A preliminary study on the pharmacology of the compound prescription huangqin tang and its component drugs]. PubMed: Inhibition of mouse liver sialidase by the root of Scutellaria baicalensis. PubMed: Effects of certain herbal medicines on the biotransformation of arachidonic acid: a new pharmacological testing method using serum. PubMed: [Studies on the constituents of Scutellaria species. VI. On the flavonoid constituents of the root of Scutellaria baicalensis Georgi (5). Quantitative analysis of flavonoids in Scutellaria roots by high-performance liquid chromatography]. PubMed: [Studies on the constituents of Scutellaria species. IV. On the flavonoid constituents of the root of Scutellaria baicalensis Georgi (4)]. PubMed: [Studies on the constituents of Scutellaria species. III. On the flavonoid constituents of the root of Scutellaria baicalensis Georgi (3)].