sucrose palmitate

sucrose monopalmitate

C28 H52 O12 MW: 580.71284000

Identification

Namesucrose palmitate
EINECS254-410-1
FDA UNIISearch
Molecular FormulaC28 H52 O12
Molecular Weight580.71284000
MDL NumberMFCD00047545
XlogP33.60 (est)

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesGRN 248
FEMA Number4713
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)26446-38-8 ; SUCROSE MONOPALMITATE

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 748.00 to 451.00 °C. @ 760.00 mm Hg (est)
Flash Point 453.00 °F. TCC ( 233.70 °C. ) (est)
logP (o/w) 4.244 (est)
Soluble in water, 0.2706 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryemollients, emulsifiers, surfactants
Recommendation for sucrose palmitate usage levels up tonot for fragrance use.
baked goods4.00000
beverages(nonalcoholic)0.20000
beverages(alcoholic)0.20000
breakfast cereal0.10000
cheese0.10000
chewing gum0.50000
condiments / relishes5.00000
confectionery froastings0.50000
egg products0.10000
fats / oils0.10000
fish products0.10000
frozen dairy0.10000
fruit ices0.10000
gelatins / puddings0.10000
granulated sugar-
gravies0.10000
hard candy0.10000
imitation dairy0.50000
instant coffee / tea0.10000
jams / jellies0.10000
meat products0.10000
milk products0.50000
nut products0.10000
other grains0.10000
poultry0.10000
processed fruits0.10000
processed vegetables0.10000
reconstituted vegetables0.10000
seasonings / flavors0.10000
snack foods0.10000
soft candy0.10000
soups0.10000
sugar substitutes0.10000
sweet sauces0.50000

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Potential Uses

emulsifying agents surfactants

Natural Occurrence

not found in nature

Synonyms

[(2S,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4- dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hexadecanoate a-D- glucopyranoside, 3-O-(1-oxohexadecyl)-b-D-fructofuranosyl 3-O- hexadecanoyl-b-D-fructofuranosyl a-D-glucopyranoside nitto ester T-1570 palmitic acid sucrose ester palmitic acid sucrose monoester 3-O- palmitoyl-b-D-fructofuranosyl a-D-glucopyranoside sucrapan P sucrodet sucrose monopalmitate sucrose palmitic acid ester Google Patents: Process for Solubilization of Flavor Oils PubMed: Development and evaluation of optimized sucrose ester stabilized oleanolic acid nanosuspensions prepared by wet ball milling with design of experiments. Leffingwell & Associates: Flavor Properties of FEMA GRAS List 25 flavor chemicals Google Patents: Process for Solubilization of Flavor Oils PubMed: Impact of Environmental Stresses on Orange Oil-in-Water Emulsions Stabilized by Sucrose Monopalmitate and Lysolecithin. PubMed: Thermal degradation kinetics of sucrose palmitate reinforced poly(lactic acid) biocomposites. PubMed: Impact of surfactants on the crystal growth of amorphous celecoxib. PubMed: Supersaturatable formulations for the enhanced oral absorption of sirolimus. PubMed: Formulation and in vitro characterization of inhalable polyvinyl alcohol-free rifampicin-loaded PLGA microspheres prepared with sucrose palmitate as stabilizer: efficiency for ex vivo alveolar macrophage targeting. PubMed: Palmitic acid analogs exhibit nanomolar binding affinity for the HIV-1 CD4 receptor and nanomolar inhibition of gp120-to-CD4 fusion. PubMed: Study of gel-forming properties of sucrose esters for thermosensitive drug delivery systems. PubMed: Enhanced bactericidal activity of enterocin AS-48 in combination with essential oils, natural bioactive compounds and chemical preservatives against Listeria monocytogenes in ready-to-eat salad. PubMed: Rheological properties of wormlike micellar solutions being available in wide temperature range in sucrose palmitate systems. PubMed: Calorimetric evaluations of Bacillus subtilis vegetative and spore cells colonial growth and suppressive effects of sucrose monopalmitate. PubMed: Preparation and characterization of a new lipid nano-emulsion containing two cosurfactants, sodium palmitate for droplet size reduction and sucrose palmitate for stability enhancement. PubMed: PFGSE-NMR study of the self-diffusion of sucrose fatty acid monoesters in water. PubMed: Sucrose Derivative Surfactants Studied by Inverse Gas Chromatography. PubMed: Effects of addition of hydrophobic sucrose fatty acid oligoesters on crystallization rates of n-hexadecane in oil-in-water emulsions. PubMed: Bacterial spore inhibition and inactivation in foods by pressure, chemical preservatives, and mild heat. PubMed: Lipase-catalyzed regioselective acylation of sucrose in two-solvent mixtures. PubMed: Synergist effect of sucrose fatty acid esters on nisin inhibition of gram-positive bacteria. PubMed: Brominated detergents as tools to study protein-detergent interactions. PubMed: Improved oral absorption of a poorly water-soluble drug, HO-221, by wet-bead milling producing particles in submicron region. PubMed: Structure-activity study of inhibition of amphotericin B (Fungizone) binding to sterols, toxicity to cells, and lethality to mice by esters of sucrose. PubMed: Studies on sucrose-palmitate-stearate-containing vesicles encapsulating the cytostatic drug methylglyoxal-bis-guanyl-hydrazone. PubMed: Cross-linked sodium carboxymethylcellulose as a carrier for dissolution rate improvement of drugs. PubMed: [Isolation of a homogeneous functionally active beta-adrenergic receptor from bovine cerebellum using lauroyl sucrose. Effect of trypsin on receptor activity]. PubMed: Studies on the metabolic fate of sucrose esters in rats. PubMed: [Saccharose esters as new auxillary substances in pharmacy. VII. Effect of sucrose monopalmitate on the biologic availability of sulfathiazole from suspensions]. PubMed: Modified substrates and modified products as inducers of carbohydrases. PubMed: Surfactants as stimulants of enzyme production by microorganisms.