gamma-heptalactone

heptano-1,4-lactone

CAS: 105-21-5 C7 H12 O2 MW: 128.17104000 coconut lactonic

Identification

Namegamma-heptalactone
IUPAC5-propyloxolan-2-one
CAS Number105-21-5
EINECS203-279-9
FDA UNIIU4XIN3U7DH
Molecular FormulaC7 H12 O2
Molecular Weight128.17104000
MDL NumberMFCD00036498
Nikkaji NumberJ79.443K
Beilstein0109569
CoE Number2253
XlogP31.10 (est)

Regulatory

JECFA Food Flavoring225 gamma-heptalactone
DG SANTE Food Flavourings10.020 heptano-1,4-lactone
FEMA Number2539
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)105-21-5 ; GAMMA-HEPTALACTONE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless clear oily liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed Yes
Specific Gravity 0.99700 to 1.00400 @ 25.00 °C.
Pounds per Gallon - (est). 8.296 to 8.354
Refractive Index 1.43900 to 1.44500 @ 20.00 °C.
Boiling Point 61.00 to 62.00 °C. @ 2.00 mm Hg, 100.00 to 106.00 °C. @ 7.00 mm Hg
Acid Value 2.00 max. KOH/g
Vapor Pressure 0.083000 mmHg @ 25.00 °C. (est)
Vapor Density >1 ( Air = 1 )
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w) 0.923 (est)
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium ,
Substantivity 400 hour(s) at 100.00 %
Odor Description
at 10.00 % in dipropylene glycol.
Sweet, coconut, coumarin, Iactonic, creamy and powdery
A waxy, creamy, coconut character
sweet-herbaceous, coconut-, hay-, coumarin-like; tobacco-note
Odor sample from CA Aromatics Company Inc.
Taste Description
at 15.00 ppm.
Sweet lactonic, hay, coumarin
sweet, lactonic, creamy, coconut and coumarin, with milky and tobacco nuances

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicityoral-rat LD50 > 5000 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for gamma-heptalactone usage levels up to8.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)170.00 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

FL asparagus FR berry FL caramel FR christmas FR coconut FR cream FR filbert FR floral FR fruit FR gardenia FR herbal FL leek FR mango FR maple FL milk FL nut FR papaya FR passion fruit FR peach FR strawberry FL tea FR tobacco trassi FR vanilla

Natural Occurrence

asparagus beef PMC beer PMC leek mango fruit papaya fruit passion fruit peach fruit peach fruit strawberry wild strawberry fruit tea green tea

Synonyms

dihydro-5-propyl-2(3H)-furanone gamma- eptalactone furan-2-one, dihydro-5-propyl- 2(3H)- furanone, dihydro-5-propyl- gamma- hepta lactone gamma heptalactone gamma- heptalactone FCC heptalactone gamma gamma- heptalactone natural heptan-4-olide heptano-1,4-lactone gamma- heptanolactone (±)-4- heptanolide 1,4- heptanolide 4- heptanolide 4- hydroxyheptanoic acid gamma-lactone 4- hydroxyheptanoic acid lactone gamma- propiobutyrolactone 4- propyl butan-4-olide 5- propyl-2-oxolanone 4- propyl-4-hydroxybutanoic acid lactone 4-N- propyl-4-hydroxybutanoic acid lactone 5- propyl-dihydro-furan-2-one gamma- propyl-gamma-butyrolactone 4- propylbutan-4-olide 5- propyldihydrofuran-2(3H)-one 5- propyloxolan-2-one PubMed: Microbial metabolism of quorum-sensing molecules acyl-homoserine lactones, γ-heptalactone and other lactones. PubMed: 6-Pentyl-2H-pyran-2-one: a potent peach-derived kairomone for New Zealand flower thrips, Thrips obscuratus. PubMed: γ-Heptalactone is an endogenously produced quorum-sensing molecule regulating growth and secondary metabolite production by Aspergillus nidulans. PubMed: Growth biostimulation of quorum-quenching bacteria by gammagamma-heptalactone treatment in the hydroponic rhizosphere of Solanum tuberosum. PubMed: Efficient biostimulation of native and introduced quorum-quenching Rhodococcus erythropolis populations is revealed by a combination of analytical chemistry, microbiology, and pyrosequencing. PubMed: Evidence of starch inclusion complexation with lactones.