Identification

Namecubeb fruit
IUPACpiper cubeba l.
CAS Number977000-82-0
FDA UNIISearch

Regulatory

FEMA Number2338
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)977000-82-0 ; CUBEB (PIPER CUBEBA L. F.)
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Food Chemicals Codex Listed No

Organoleptic Properties

Odor Description at 100.00 %.
Taste Description cubeb

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryspices, other natural seasonings and flavorings
Recommendation for cubeb fruit usage levels up tonot for fragrance use.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

No supplier data available

Potential Uses

None Found

Natural Occurrence

cubeb

Synonyms

cubeb pepper piper cubeba fruit PubMed: Anticancer activity studies of cubebin isolated from Piper cubeba and its synthetic derivatives. PubMed: Evaluation of lignan (-)-cubebin extracted from Piper cubeba on human colon adenocarcinoma cells (HT29). PubMed: Cytotoxic activity of Piper cubeba extract in breast cancer cell lines. PubMed: Evaluation of the effectiveness of Piper cubeba extract in the amelioration of CCl4-induced liver injuries and oxidative damage in the rodent model. PubMed: Biological activities of Zingiber officinale (Zingiberaceae) and Piper cubeba (Piperaceae) essential oils against pulse beetle, Callosobruchus chinensis (Coleoptera: Bruchidae). PubMed: In vitro antiparasitic activity and chemical composition of the essential oil obtained from the fruits of Piper cubeba. PubMed: Variation in manuka oil lure efficacy for capturing Xyleborus glabratus (Coleoptera: Curculionidae: Scolytinae), and cubeb oil as an alternative attractant. PubMed: A comparative study of the modulatory effects of (-)-cubebin on the mutagenicity/recombinogenicity induced by different chemical agents. PubMed: The lignan (-)-cubebin inhibits vascular contraction and induces relaxation via nitric oxide activation in isolated rat aorta. PubMed: Mutagenicity and antimutagenicity of (-)-hinokinin a trypanosomicidal compound measured by Salmonella microsome and comet assays. PubMed: Nephroprotective effect of Kabab chini (Piper cubeba) in gentamycin-induced nephrotoxicity. PubMed: Screening of immunomodulatory activity of total and protein extracts of some Moroccan medicinal plants. PubMed: Identification of ambiguous cubeb fruit by DART-MS-based fingerprinting combined with principal component analysis. PubMed: Essential and toxic elements in three Pakistan's medicinal fruits (Punica granatum, Ziziphus jujuba and Piper cubeba) analysed by INAA. PubMed: In vitro efficacy of the essential oil of Piper cubeba L. (Piperaceae) against Schistosoma mansoni. PubMed: Radical scavenging ability of some compounds isolated from Piper cubeba towards free radicals. PubMed: Was the famous astronomer Copernicus also a nephrologist. PubMed: The effect of the dibenzylbutyrolactolic lignan (-)-cubebin on doxorubicin mutagenicity and recombinogenicity in wing somatic cells of Drosophila melanogaster. PubMed: Effect of the dibenzylbutyrolactone lignan (-)-hinokinin on doxorubicin and methyl methanesulfonate clastogenicity in V79 Chinese hamster lung fibroblasts. PubMed: Molluscicidal activity of Piper cubeba Linn., Piper longum Linn. and Tribulus terrestris Linn. and their combinations against snail Indoplanorbis exustus Desh. PubMed: Piper cubeba demonstrates anti-estrogenic and anti-inflammatory properties. PubMed: Piper cubeba targets multiple aspects of the androgen-signalling pathway. A potential phytotherapy against prostate cancer growth? PubMed: Evaluation of piper cubeba extract, (-)-cubebin and its semi-synthetic derivatives against oral pathogens. PubMed: (-)-Hinokinin causes antigenotoxicity but not genotoxicity in peripheral blood of Wistar rats. PubMed: Effect of some medicinal plants on plasma antioxidant system and lipid levels in rats. PubMed: Metabolite-cytochrome P450 complex formation by methylenedioxyphenyl lignans of Piper cubeba: mechanism-based inhibition. PubMed: Potent CYP3A4 inhibitory constituents of Piper cubeba. PubMed: Enzymatic and non-enzymatic antioxidants in selected Piper species. PubMed: Investigations of anti-inflammatory and antinociceptive activities of Piper cubeba, Physalis angulata and Rosa hybrida. PubMed: Inhibitory effects of sudanese medicinal plant extracts on hepatitis C virus (HCV) protease. PubMed: [Constituents of Aristolochia triangularis]. PubMed: Comparison of vegetative anatomy of piperales. I. Juvenile xylem of twigs. PubMed: The occurrence of mature fruits of Piper cubeba in recently imported cubeb. PubMed: The problem of foreign botanicals.