fusarin C
Identification
| Name | fusarin C |
| CAS Number | 79748-81-5 |
| FDA UNII | C3F3Z00LM3 |
| Molecular Formula | C23 H29 N O7 |
| Molecular Weight | 431.48553000 |
Regulatory
Physical Properties
| Appearance | yellow liquid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 699.30 °C. @ 760.00 mm Hg (est) |
| Flash Point | 710.00 °F. TCC ( 376.70 °C. ) (est) |
| logP (o/w) | 2.050 (est) |
| Soluble in | water, 0.05914 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for fusarin C usage levels up to | not for fragrance use. |
| Recommendation for fusarin C flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
fusarin C
PubMed:
The effects of different yeast extracts on secondary metabolite production in Fusarium.
PubMed:
Influence of carbohydrates on secondary metabolism in Fusarium avenaceum.
PubMed:
Genetic manipulation of the Fusarium fujikuroi fusarin gene cluster yields insight into the complex regulation and fusarin biosynthetic pathway.
PubMed:
New approach via gene knockout and single-step chemical reaction for the synthesis of isotopically labeled fusarin c as an internal standard for the analysis of this fusarium mycotoxin in food and feed samples.
PubMed:
Identification of gene clusters associated with fusaric acid, fusarin, and perithecial pigment production in Fusarium verticillioides.
PubMed:
Segregation of secondary metabolite biosynthesis in hybrids of Fusarium fujikuroi and Fusarium proliferatum.
PubMed:
Structure elucidation of new fusarins revealing insights in the rearrangement mechanisms of the Fusarium mycotoxin fusarin C.
PubMed:
A new high-performance liquid chromatography-tandem mass spectrometry method based on dispersive solid phase extraction for the determination of the mycotoxin fusarin C in corn ears and processed corn samples.
PubMed:
Fusarin C acts like an estrogenic agonist and stimulates breast cancer cells in vitro.
PubMed:
FfVel1 and FfLae1, components of a velvet-like complex in Fusarium fujikuroi, affect differentiation, secondary metabolism and virulence.
PubMed:
Development of monoclonal antibodies for the fusarin mycotoxins.
PubMed:
Synthesis of [1,2-13C2, 15N]-L-homoserine and its incorporation by the PKS-NRPS system of Fusarium moniliforme into the mycotoxin fusarin C.
PubMed:
Production of mutagenic metabolites by Metarhizium anisopliae.
PubMed:
Functional analysis of the polyketide synthase genes in the filamentous fungus Gibberella zeae (anamorph Fusarium graminearum).
PubMed:
A novel biomimetic route to the 3-acyl-5-hydroxy-3-pyrrolin-2-one and 3-acyl-3,4-epoxy-5-hydroxypyrrolidin-2-one ring systems.
PubMed:
Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum.
PubMed:
Diversity in metabolite production by Fusarium langsethiae, Fusarium poae, and Fusarium sporotrichioides.
PubMed:
DNA adduct formation by Fusarium culture extracts: lack of role of fusarin C.
PubMed:
Aeration affects acetate destination in Gibberella fujikuroi.
PubMed:
Detection of fusarin C and trichothecenes in Fusarium strains from Spain.
PubMed:
Fusarin C, (7Z)-fusarin C and (5Z)-fusarin C; inhibitors of dihydroxynaphthalene-melanin biosynthesis from Nectria coccinea (Cylindrocarpon sp.).
PubMed:
Fusarium species associated with banana fruit rot and their potential toxigenicity.
PubMed:
Mycoflora and Fusarium toxins of three types of corn grains in Egypt with special reference to production of trichothecene-toxins.
PubMed:
Glucose and zinc concentration influence fusarin C synthesis, ethanol synthesis and lipid composition in Fusarium moniliforme submerged cultures.
PubMed:
Fusarin C: isolation and identification of two microsomal metabolites.
PubMed:
Isolation, structural identification, and characterization of a mutagen from Fusarium moniliforme.
PubMed:
Toxins derived from Fusarium moniliforme: fumonisins B1 and B2 and fusarin C.
PubMed:
Effects of selected secondary metabolites of Fusarium moniliforme on unscheduled synthesis of DNA by rat primary hepatocytes.
PubMed:
[Method of producing fusarin C in perlite-liquid culture medium].
PubMed:
Stability of fusarin C: effects of the normal cooking procedure used in China and pH.
PubMed:
[Fusarin C induced esophageal and forestomach carcinoma in mice and rats].
PubMed:
In vitro transformation of rat esophageal epithelial cells by fusarin C.
PubMed:
Do the pigments differ chemotaxonomically fungi belonging to genusFusarium?
PubMed:
Mutagenicity of potentially carcinogenic mycotoxins produced byFusarium moniliforme.
PubMed:
Immunosuppressive effects of Fusarium moniliforme corn cultures in chickens.
PubMed:
The influence of carbon and nitrogen nutrition on fusarin C biosynthesis by Fusarium moniliforme.
PubMed:
Differential cytotoxicity and mycotoxin content among isolates of Fusarium moniliforme.
PubMed:
Mycotoxin formation by different geographic isolates of Fusarium crookwellense.
PubMed:
[The metabolism and DNA binding of 3H-fusarin C in rats].
PubMed:
Absence of trichothecenes in toxigenic isolates of Fusarium moniliforme.
PubMed:
Production of fusarin C on cereal and soybean by Fusarium moniliforme.
PubMed:
Metabolism of fusarin C by rat liver microsomes. Role of esterase and cytochrome P-450 enzymes with respect to the mutagenicity of fusarin C in Salmonella typhimurium.
PubMed:
Production of trichothecene and non-trichothecene mycotoxins by Fusarium species isolated from maize in Minnesota.
PubMed:
Effects of zinc, iron, cobalt, and manganese on Fusarium moniliforme NRRL 13616 growth and fusarin C biosynthesis in submerged cultures.
PubMed:
Mycotoxins produced by toxic Fusarium isolates obtained from agricultural and nonagricultural areas (Arctic) of Norway.
PubMed:
Mycotoxin production by Fusarium oxysporum and Fusarium sporotrichioides isolated from Baccharis spp. from Brazil.
PubMed:
Fusarium moniliforme Sheld. A fungus producing a broad spectrum of bioactive metabolites.
PubMed:
Current views on the occurrence and significance of Fusarium toxins.
PubMed:
Investigations on the spectral interactions of fusarin C with rat liver microsomal cytochrome P-450.
PubMed:
Fusarium moniliforme metabolites: genotoxicity of culture extracts.
PubMed:
Formation of fusarenone X, nivalenol, zearalenone, alpha-trans-zearalenol, beta-trans-zearalenol, and fusarin C by Fusarium crookwellense.
PubMed:
The chemical and enzymatic interaction of glutathione with the fungal metabolite, fusarin C.
PubMed:
Screening for Fusarin C production by European isolates of Fusarium species.
PubMed:
Production of moniliformin by Canadian isolates of Fusarium.
PubMed:
[Method of chemical determination of fusarin C].
PubMed:
The role of rat liver microsomal enzymes in the metabolism of the fungal metabolite fusarin C.
PubMed:
Standardized high-performance liquid chromatography of 182 mycotoxins and other fungal metabolites based on alkylphenone retention indices and UV-VIS spectra (diode array detection).
PubMed:
Immuno-deficiency acquired during carcinogenesis: a mechanism facilitating cancer development.
PubMed:
Carcinogenicity of Fusarium moniliforme culture material in rats.
PubMed:
[Modulation of macrophage-mediated cytotoxic activity. III. Effect of fusarin C on macrophage-mediated cytotoxic activity].
PubMed:
Investigations on the carcinogenicity of fusarin C--a mutagenic metabolite of Fusarium moniliforme.
PubMed:
Fusarin C production by North American isolates of Fusarium moniliforme.
PubMed:
[Studies on a new mutagen produced by fusarium moniliforme isolated in Linxian County].
PubMed:
A mutagenic metabolite produced by Fusarium moniliforme isolated from Linxian county, China.
PubMed:
Metabolic activation and deactivation of fusarin C, a mutagen produced by Fusarium moniliforme.