isoxaflutole

methanone, (5-cyclopropyl-4-isoxazolyl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]-

CAS: 141112-29-0 C15 H12 F3 N O4 S MW: 359.32464960

Identification

Nameisoxaflutole
IUPAC(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone
CAS Number141112-29-0
FDA UNII0T9R0O0EYT
Molecular FormulaC15 H12 F3 N O4 S
Molecular Weight359.32464960
MDL NumberMFCD03095707
Nikkaji NumberJ794.343A

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 140.00 °C. @ 760.00 mm Hg
Boiling Point 575.06 °C. @ 760.00 mm Hg (est)
Vapor Pressure 7.500000 mmHg @ 25.00 °C. (est)
Flash Point 575.00 °F. TCC ( 301.60 °C. ) (est)
logP (o/w) 2.320
Soluble in water, 56.8 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for isoxaflutole usage levels up tonot for fragrance use.
Recommendation for isoxaflutole flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

(5- cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone (5- cyclopropyl-1,2-oxazol-4-yl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]methanone 5- cyclopropyl-4-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]isoxazole (5- cyclopropyl-4-isoxazolyl)(2-(methylsulfonyl)-4-(trifluoromethyl)phenyl)methanone (5- cyclopropyl-4-isoxazolyl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]methanone (5- cyclopropylisoxazol-4-yl)(2-(methylsulfonyl)-4-(trifluoromethyl)phenyl)methanone (5- cyclopropylisoxazol-4-yl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]methanone 4-(2- methanesulphonyl-4-trifluoromethylbenzoyl)-5-cyclopropyl isoxazole methanone, (5-cyclopropyl-4-isoxazolyl)(2-(methylsulfonyl)-4-(trifluoromethyl)phenyl)- methanone, (5-cyclopropyl-4-isoxazolyl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]- PubMed: Effect of buffer strips and soil texture on runoff losses of flufenacet and isoxaflutole from maize fields. PubMed: Water pressure head and temperature impact on isoxaflutole degradation in crop residues and loamy surface soil under conventional and conservation tillage management. PubMed: Variability of retention process of isoxaflutole and its diketonitrile metabolite in soil under conventional and conservation tillage. PubMed: Sensitivity of locally naturalized Panicum species to HPPD- and ALS-inhibiting herbicides in maize. PubMed: Adsorption of isoxaflutole degradates to aluminum and iron hydrous oxides. PubMed: Investigation of endogenous soybean food allergens by using a 2-dimensional gel electrophoresis approach. PubMed: Bioavailability of diuron, imazapic and isoxaflutole in soils of contrasting textures. PubMed: [Screening method of pesticides in meat using cleanup with GPC and mini-column]. PubMed: Role of sorption and degradation in the herbicidal function of isoxaflutole. PubMed: Temperature and water pressure head effects on the degradation of the diketonitrile metabolite of isoxaflutole in a loamy soil under two tillage systems. PubMed: Comparison of fate and transport of isoxaflutole to atrazine and metolachlor in 10 Iowa rivers. PubMed: Processes affecting the dissipation of the herbicide isoxaflutole and its diketonitrile metabolite in agricultural soils under field conditions. PubMed: Influence of rainfall distribution on simulations of atrazine, metolachlor, and isoxaflutole/metabolite transport in subsurface drained fields. PubMed: Improved HPLC-MS/MS method for determination of isoxaflutole (balance) and its metabolites in soils and forage plants. PubMed: Development and validation of a multi-residue method for pesticide determination in honey using on-column liquid-liquid extraction and liquid chromatography-tandem mass spectrometry. PubMed: Differential response of chickpea genotypes to isoxaflutole. PubMed: Influence of an adjuvant on the distribution of herbicides in a sediment/water system. PubMed: Reaction pathways of the diketonitrile degradate of isoxaflutole with hypochlorite in water. PubMed: Sorption of isoxaflutole diketonitrile degradate (DKN) and dicamba in unsaturated soil. PubMed: Characterization of fate and transport of isoxaflutole, a soil-applied corn herbicide, in surface water using a watershed model. PubMed: Effect of soil properties on the degradation of isoxaflutole and the sorption-desorption of isoxaflutole and its diketonitrile degradate. PubMed: Population dynamics of Digitaria spp submitted to selection pressure by herbicides in sugarcane crop. PubMed: Degradation of RPA 202248 [U-14C-phenyl]alpha(-(cyclopropylcarbonyl)-2-(methylsulfonyl)-beta-oxo-4-(trifluromethyl)benzenepropanenitrile), the primary degradation product of isoxaflutole, in an outdoor aquatic microcosm system. PubMed: Interrelationship of macropores and subsurface drainage for conservative tracer and pesticide transport. PubMed: Reversal of the inhibition of photosynthesis by herbicides affecting hydroxyphenylpyruvate dioxygenase by plastoquinone and tocopheryl derivatives in Chlamydomonas reinhardtii. PubMed: Sorption and desorption of the diketonitrile metabolite of isoxaflutole in soils. PubMed: Degradation of isoxaflutole (balance) herbicide by hypochlorite in tap water. PubMed: The effect of five forage species on transport and transformation of atrazine and isoxaflutole (balance) in lysimeter leachate. PubMed: Soil persistence of 4-HPPD-inhibitors in different soil types. PubMed: Fate of isoxaflutole in soil under controlled conditions. PubMed: Fate of the herbicide isoxaflutole in the soil of corn fields. PubMed: Determination of isoxaflutole (balance) and its metabolites in water using solid phase extraction followed by high-performance liquid chromatography with ultraviolet or mass spectrometry. PubMed: Effects of moisture, temperature, and biological activity on the degradation of isoxaflutole in soil. PubMed: Soil metabolism of isoxaflutole in corn. PubMed: Kinetics of chemical degradation of isoxaflutole: influence of the nature of aqueous buffers (alkanoic acid/sodium salt vs phosphate). PubMed: Isoxaflutole: the background to its discovery and the basis of its herbicidal properties. PubMed: Cleavage of the diketonitrile derivative of the herbicide isoxaflutole by extracellular fungal oxidases. PubMed: Kinetics of abiotic hydrolysis of isoxaflutole: influence of pH and temperature in aqueous mineral buffered solutions. PubMed: Inhibition of p-hydroxyphenylpyruvate dioxygenase by the diketonitrile of isoxaflutole: a case of half-site reactivity. PubMed: Spectroscopic study of the sorption of isoxaflutole and its diketonitrile metabolite in dissimilar soils.