lovastatin

altocor altoprev antibiotic MB 530B butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (2S) cholestra colevix 2b,6a- dimethyl-8a-(2-methyl-1-oxobutoxy)mevinic acid lactone (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a- hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl (S)-2-Methylbutyrate hipovastin [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4- hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4- hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate lovastatinum 6-a- methylcompactin mevinacor monacolin K monakolin K paschol PubMed: Antihepatoma and liver protective potentials of ganoderma lucidum ( ling zhi) fermented in a medium containing black soybean ( hēi dòu) and astragalus membranaceus ( shēng huáng qí). PubMed: Insights into Monascus biology at the genetic level. PubMed: Mevalonate deprivation mediates the impact of lovastatin on the differentiation of murine 3T3-F442A preadipocytes. PubMed: Statin-associated lower urinary tract symptoms: data mining of the public version of the FDA adverse event reporting system, FAERS. PubMed: Antiobesity and vasoprotective effects of resveratrol in apoE-deficient mice. PubMed: Pharmacokinetic drug-drug interactions between 1,4-dihydropyridine calcium channel blockers and statins: factors determining interaction strength and relevant clinical risk management. PubMed: National Drug Formulary review of statin therapeutic group using the multiattribute scoring tool. PubMed: [Hypolipidemic agents drug interactions: approach to establish and assess its clinical significance. Structured review]. PubMed: Several statins increase body and liver fat accumulation in a model of metabolic syndrome. PubMed: Stability of monacolin K and citrinin and biochemical characterization of red-koji vinegar during fermentation. PubMed: Effects of Monascus-fermented grain extracts on plasma antioxidant status and tissue levels of ubiquinones and α-tocopherol in hyperlipidemic rats. PubMed: Strain improvement by overexpression of the laeA gene in Monascus pilosus for the production of monascus-fermented rice. PubMed: Comparative study of contents of several bioactive components in fruiting bodies and mycelia of culinary-medicinal mushrooms. PubMed: Genome-scale reconstruction and in silico analysis of Aspergillus terreus metabolism. PubMed: Exposure assessment of lovastatin in Pu-erh tea. PubMed: Review of red yeast rice content and current Food and Drug Administration oversight. PubMed: Monascus-fermented yellow pigments monascin and ankaflavin showed antiobesity effect via the suppression of differentiation and lipogenesis in obese rats fed a high-fat diet. PubMed: Development of a rapid LC/DAD/FLD/MS(n) method for the simultaneous determination of monacolins and citrinin in red fermented rice products. PubMed: Simultaneous determination of lovastatin and citrinin in red yeast rice supplements by micellar electrokinetic capillary chromatography. PubMed: Monascin and ankaflavin have more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity than monacolin K under the same dosages. PubMed: Boceprevir: a recently approved protease inhibitor for hepatitis C virus infection. PubMed: The effect of red yeast rice (Monascus purpureus) in dyslipidemia and other disorders. PubMed: Dietary Monascus adlay supplements facilitate suppression of cigarette smoke-induced pulmonary endoplasmic reticulum stress, autophagy, apoptosis and emphysema-related PLGF in the rat. PubMed: Red mold dioscorea: a potentially safe traditional function food for the treatment of hyperlipidemia. PubMed: What is a food and what is a medicinal product in the European Union? Use of the benchmark dose (BMD) methodology to define a threshold for "pharmacological action". PubMed: A survey of the FDA's AERS database regarding muscle and tendon adverse events linked to the statin drug class. PubMed: Effect of hydroalcoholic extract of Hypericum perforatum on selected traditional and novel biochemical factors of cardiovascular diseases and atherosclerotic lesions in hypercholesterolemic rabbits: A comparison between the extract and lovastatin. PubMed: A statin-regulated microRNA represses human c-Myc expression and function. PubMed: The natural carotenoid astaxanthin, a PPAR-α agonist and PPAR-γ antagonist, reduces hepatic lipid accumulation by rewiring the transcriptome in lipid-loaded hepatocytes. PubMed: Development of monacolin K-enriched ganghwayakssuk (Artemisia princeps Pamp.) by fermentation with Monascus pilosus. PubMed: [Cholesterol-degrading in mice by Lactobacillus plantarum LpT1 and LpT2 in vivo]. PubMed: NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements. PubMed: Comparison of prescription drug costs in the United States and the United Kingdom, Part 1: statins. PubMed: Cytotoxic dehydromonacolins from red yeast rice. PubMed: Comparative study of contents of several bioactive components in fruiting bodies and mycelia of culinary-medicinal mushrooms. PubMed: Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress. PubMed: Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism. PubMed: Fast screening of lovastatin in red yeast rice products by flow injection tandem mass spectrometry. PubMed: Antioxidant effect of red mould rice in hypercholesterolemic Wistar male rats. PubMed: Osteoprotective effect of Monascus-fermented dioscorea in ovariectomized rat model of postmenopausal osteoporosis. PubMed: Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. PubMed: Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. PubMed: Polysorbates as novel lipid-modulating candidates for reducing serum total cholesterol and low-density lipoprotein levels in hyperlipidemic C57BL/6J mice and rats. PubMed: Inhibition of endothelial adhesion molecule expression by Monascus purpureus-fermented rice metabolites, monacolin K, ankaflavin, and monascin. PubMed: Synchronous high-performance liquid chromatography with a photodiode array detector and mass spectrometry for the determination of citrinin, monascin, ankaflavin, and the lactone and acid forms of monacolin K in red mold rice. PubMed: Role of intestinal cytochrome P450 (P450) in modulating the bioavailability of oral lovastatin: insights from studies on the intestinal epithelium-specific P450 reductase knockout mouse. PubMed: Chinese red yeast rice inhibition of prostate tumor growth in SCID mice. PubMed: Elevated yield of monacolin K in Monascus purpureus by fungal elicitor and mutagenesis of UV and LiCl. PubMed: d-δ-Tocotrienol-mediated cell cycle arrest and apoptosis in human melanoma cells. PubMed: The effect of lovastatin on oxidative stress and antioxidant enzymes in hydrogen peroxide intoxicated rat. PubMed: What combination therapy with a statin, if any, would you recommend? PubMed: Marked variability of monacolin levels in commercial red yeast rice products: buyer beware! PubMed: Conversion investigation for lovastatin and its derivatives by HPLC. PubMed: Red yeast rice stimulates osteoblast proliferation and increases alkaline phosphatase activity in MC3T3-E1 cells. PubMed: Finger millet (Eleusine coracana) - an economically viable source for antihypercholesterolemic metabolites production by Monascus purpureus. PubMed: Statins: 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors demonstrate anti-atherosclerotic character due to their antioxidant capacity. PubMed: [With red rice against cholesterol?]. PubMed: [Establishment of a model for evaluating hypolipidemic effect in HepG2 cells]. PubMed: Major diet-drug interactions affecting the kinetic characteristics and hypolipidaemic properties of statins. PubMed: Red mold rice promotes neuroprotective sAPPalpha secretion instead of Alzheimer's risk factors and amyloid beta expression in hyperlipidemic Abeta40-infused rats. PubMed: Response surface methodology for optimization of production of lovastatin by solid state fermentation. PubMed: Red Mold Rice Mitigates Oral Carcinogenesis in 7,12-Dimethyl-1,2-Benz[a]anthracene-Induced Oral Carcinogenesis in Hamster. PubMed: Identification of the mokH gene encoding transcription factor for the upregulation of monacolin K biosynthesis in Monascus pilosus. PubMed: Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism. PubMed: The Monascus metabolite monacolin K reduces tumor progression and metastasis of Lewis lung carcinoma cells. PubMed: A comparison of pectin, polyphenols, and phytosterols, alone or in combination, to lovastatin for reduction of serum lipids in familial hypercholesterolemic swine. PubMed: Hypolipidemic effects of Monascus-fermented soybean extracts in rats fed a high-fat and -cholesterol diet. PubMed: Effect of precultural and nutritional parameters on compactin production by solid-state fermentation. PubMed: High-dose lovastatin for acute ischemic stroke: results of the phase I dose escalation neuroprotection with statin therapy for acute recovery trial (NeuSTART). PubMed: Concurrent use of statins and amiodarone. PubMed: Safety evaluation of Monascus purpureus red mould rice in albino rats. PubMed: d-δ-Tocotrienol-mediated suppression of the proliferation of human PANC-1, MIA PaCa-2, and BxPC-3 pancreatic carcinoma cells. PubMed: Red yeast rice fermentation by selected Monascus sp. with deep-red color, lovastatin production but no citrinin, and effect of temperature-shift cultivation on lovastatin production. PubMed: Effects of rutin on lipid profile in hypercholesterolaemic rats. PubMed: Anti-hyperlipidemic effect of an edible brown algae, Ecklonia stolonifera, and its constituents on poloxamer 407-induced hyperlipidemic and cholesterol-fed rats. PubMed: Compactin production studies using Penicillium brevicompactum under solid-state fermentation conditions. PubMed: Chinese red yeast rice versus lovastatin effects on prostate cancer cells with and without androgen receptor overexpression. PubMed: Defective rotavirus particle assembly in lovastatin-treated MA104 cells. PubMed: Grapefruit juice-drug interaction studies as a method to assess the extent of intestinal availability: utility and limitations. PubMed: SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice. PubMed: An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA's spontaneous adverse event reporting system. PubMed: Comparative evaluation of the hypolipidemic effects of coconut water and lovastatin in rats fed fat-cholesterol enriched diet. PubMed: Red mold rice prevents the development of obesity, dyslipidemia and hyperinsulinemia induced by high-fat diet. PubMed: Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin. PubMed: Cloning and characterization of monacolin K biosynthetic gene cluster from Monascus pilosus. PubMed: The safety of niacin in the US Food and Drug Administration adverse event reporting database. PubMed: Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention. PubMed: Mevinolin, citrinin and pigments of adlay angkak fermented by Monascus sp. PubMed: Fixed-dose combination therapy with statins: strengths, limitations, and clinical and regulatory considerations. PubMed: Red mold rice extract represses amyloid beta peptide-induced neurotoxicity via potent synergism of anti-inflammatory and antioxidative effect. PubMed: The Food and Drug Administration and over-the-counter statins: an opportunity lost? PubMed: FDA advisers again reject nonprescription lovastatin. PubMed: A simple and rapid approach for removing citrinin while retaining monacolin K in red mold rice. PubMed: The potential antioxidant capacity and angiotensin I-converting enzyme inhibitory activity of Monascus-fermented soybean extracts: evaluation of Monascus-fermented soybean extracts as multifunctional food additives. PubMed: Monascus rice products. PubMed: Optimization of production of monacolin K from gamma-irradiated Monascus mutant by use of response surface methodology. PubMed: Anticancer effects of Chinese red yeast rice versus monacolin K alone on colon cancer cells. PubMed: Red mold rice ameliorates impairment of memory and learning ability in intracerebroventricular amyloid beta-infused rat by repressing amyloid beta accumulation. PubMed: Red mold dioscorea has greater hypolipidemic and antiatherosclerotic effect than traditional red mold rice and unfermented dioscorea in hamsters. PubMed: Improving the ratio of monacolin K to citrinin production of Monascus purpureus NTU 568 under dioscorea medium through the mediation of pH value and ethanol addition. PubMed: Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction. PubMed: Esterase inhibition attribute of grapefruit juice leading to a new drug interaction. PubMed: Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system). PubMed: Influences of lovastatin on membrane ion flow and intracellular signaling in breast cancer cells. PubMed: Elevated K-ras activity with cholestyramine and lovastatin, but not konjac mannan or niacin in lung--importance of mouse strain. PubMed: Proteomic analysis of Caco-2 cells treated with monacolin K. PubMed: Synchronous analysis method for detection of citrinin and the lactone and acid forms of monacolin K in red mold rice. PubMed: Grape fruit juice-drug interactions. PubMed: Lovastatin has significant activity against zygomycetes and interacts synergistically with voriconazole. PubMed: Enzymatic examination of potential interaction between statins or fibrates and consumed Tricholoma equestre. PubMed: Risks of a nonprescription lovastatin. PubMed: Study on red fermented rice with high concentration of monacolin K and low concentration of citrinin. PubMed: Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions. PubMed: FDA advisers vote against nonprescription lovastatin. PubMed: OTC status for low-dose lovastatin would have widespread implications. PubMed: Effect of 3,4-di(OH)-cinnamate synthetic derivative on plasma and hepatic cholesterol level and antioxidant enzyme activities in high cholesterol-fed rats. PubMed: Modified mutation method for screening low citrinin-producing strains of Monascus purpureus on rice culture. PubMed: Interactions between grapefruit juice and cardiovascular drugs. PubMed: Antihypercholesterolemic property of naringin alters plasma and tissue lipids, cholesterol-regulating enzymes, fecal sterol and tissue morphology in rabbits. PubMed: Identification and chemical profiling of monacolins in red yeast rice using high-performance liquid chromatography with photodiode array detector and mass spectrometry. PubMed: The role of maternal toxicity in lovastatin-induced developmental toxicity. PubMed: Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention. PubMed: Evaluation of hesperetin 7-O-lauryl ether as lipid-lowering agent in high-cholesterol-fed rats. PubMed: Gene transfer into human hepatoma cells by receptor-associated protein/polylysine conjugates. PubMed: Naringin alters the cholesterol biosynthesis and antioxidant enzyme activities in LDL receptor-knockout mice under cholesterol fed condition. PubMed: Effect of red mold rice supplements on serum and egg yolk cholesterol levels of laying hens. PubMed: Methyl palmitate: a novel product of the Medfly (Ceratitis capitata) corpus allatum. PubMed: Cinnamate supplementation enhances hepatic lipid metabolism and antioxidant defense systems in high cholesterol-fed rats. PubMed: [Effect of lovastatin on the expression of IkappaBalpha and cell-cycle regulating protein in MCF-7 cells]. PubMed: Treatment with lovastatin, cholestyramine or niacin alters K-ras membrane association in mouse lung in a strain-dependent manner: results in females. PubMed: Statin-associated memory loss: analysis of 60 case reports and review of the literature. PubMed: Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and C-reactive protein. PubMed: Comparison of the cholesterol-lowering effects and toxicity of D-003 and lovastatin in normocholesterolaemic rabbits. PubMed: Biosynthetic maturation of the corpus allatum of the female adult medfly, Ceratitis capitata, and its putative control. PubMed: 4-hydroxycinnamate lowers plasma and hepatic lipids without changing antioxidant enzyme activities. PubMed: Lopinavir/ritonavir: a review of its use in the management of HIV infection. PubMed: [Effects of lovastatin on proliferation and gap junctional intercellular communication of human breast cancer cell MCF-7]. PubMed: Effect of rice--glycerol complex medium on the production of Lovastatin by Monascus ruber. PubMed: Side effects of statins--prevalence, relevance, consequences. PubMed: [Effect of monascus on improving the hemorheology of rats with high blood lipids]. PubMed: Niacin-ER and lovastatin treatment of hypercholesterolemia and mixed dyslipidemia. PubMed: A dietary portfolio approach to cholesterol reduction: combined effects of plant sterols, vegetable proteins, and viscous fibers in hypercholesterolemia. PubMed: Policosanol safely down-regulates HMG-CoA reductase - potential as a component of the Esselstyn regimen. PubMed: Alterations in membrane-bound and cytoplasmic K-ras protein levels in mouse lung induced by treatment with lovastatin, cholestyramine, or niacin: effects are highly mouse strain dependent. PubMed: Food-drug interactions. PubMed: From the Food and Drug Administration. PubMed: Managing dyslipidemia in the high-risk patient. PubMed: CD43 polarization in unprimed T cells can be dissociated from raft coalescence by inhibition of HMG CoA reductase. PubMed: FDA adverse event reports on statin-associated rhabdomyolysis. PubMed: Comparative pharmacokinetics of lovastatin extended-release tablets and lovastatin immediate-release tablets in humans. PubMed: Lipid-lowering and antioxidative activities of 3,4-di(OH)-cinnamate and 3,4-di(OH)-hydrocinnamate in cholesterol-fed rats. PubMed: The role of cytochrome P450-mediated drug-drug interactions in determining the safety of statins. PubMed: Mechanism of up-regulated gap junctional intercellular communication during chemoprevention and chemotherapy of cancer. PubMed: FDA panel vetoes OTC version of cholesterol drug. PubMed: Inhibition of purified pig and human liver retinyl ester hydrolase by pharmacologic agents. PubMed: [Effect of cholesterol deficiency on the membrane fluidity of Jurkat T lymphocytes]. PubMed: New OTC drugs and devices 2000: a selective review. PubMed: Cardiovascular risk factors and testing of relatives amongst patients with familial hyperlipidaemia one decade after a clinical trial. PubMed: FDA says statin cannot be sold over the counter. PubMed: Beneficial changes in serum apo A-1 and its ratio to apo B and HDL in stable hyperlipidaemic subjects after Ramadan fasting in Kuwait. PubMed: Grapefruit juice-lovastatin interaction. PubMed: Defining patient risks from expanded preventive therapies. PubMed: Evidence that MRas1 and MRas3 proteins are associated with distinct cellular functions during growth and morphogenesis in the fungus Mucor racemosus. PubMed: Effect of dietary lipid-lowering drugs upon plasma lipids and egg yolk cholesterol levels of laying hens. PubMed: Grapefruit juice has minimal effects on plasma concentrations of lovastatin-derived 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. PubMed: Lovastatin triggers an apoptosis-like cell death process in the fungus Mucor racemosus. PubMed: Cost-effectiveness of statins. PubMed: Grapefruit juice-drug interactions. PubMed: Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. PubMed: The role of nutritional modifications in the prevention of macrovascular complications of diabetes. PubMed: FDA and Pharmanex clash over dietary supplement. PubMed: Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences. PubMed: Simvastatin further enhances the hypocholesterolemic effect of soy protein in rabbits. PubMed: Biochemical characterization of the phagocytic giant cell receptor for Dictyostelium discoideum amoebae: identification by cell blotting. PubMed: The effect of ethanol and/or food restriction on coenzyme Q in liver in rats. PubMed: Hyperlipidaemia, diet and simvastatin therapy in steroid-resistant nephrotic syndrome of childhood. PubMed: The effect of manganese-induced hypercholesterolemia on learning in rats. PubMed: Development and pharmacology of fluvastatin. PubMed: Interactions with hydroxymethylglutaryl-coenzyme A reductase inhibitors. PubMed: Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia. PubMed: Reversibility of manganese-induced learning defect in rats. PubMed: Effect of lovastatin on cholesterol content of cardiac and red blood cell membranes in normal and cardiomyopathic hamsters. PubMed: In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin. PubMed: Development and pharmacology of fluvastatin. PubMed: Clinical pharmacokinetics of pravastatin. PubMed: Clinical implications of the biopharmaceutical properties of fluvastatin. PubMed: Short-term cholesterol lowering decreases size and severity of perfusion abnormalities by positron emission tomography after dipyridamole in patients with coronary artery disease. A potential noninvasive marker of healing coronary endothelium. PubMed: In vivo regulation of hepatic lipase activity and mRNA levels by diets which modify cholesterol influx to the liver. PubMed: Lovastatin decreases plasma and platelet cholesterol levels and normalizes elevated platelet fluidity and aggregation in hypercholesterolemic patients. PubMed: Effects of ethanol, lovastatin and coenzyme Q10 treatment on antioxidants and TBA reactive material in liver of rats. PubMed: Plasma VLDL cholesterol and egg cholesterol are resistant to change in the laying hen. PubMed: HMG CoA reductase inhibitors. In vivo effects on carotid intimal thickening in normocholesterolemic rabbits. PubMed: RG 12561 (dalvastatin): a novel synthetic inhibitor of HMG-CoA reductase and cholesterol-lowering agent. PubMed: Studies on the effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on the rodent forestomach. PubMed: Pharmacological and dietary treatment of lipid abnormalities in nephrotic patients. PubMed: Oxysterols, cholesterol biosynthesis, and vascular endothelial cell monolayer barrier function. PubMed: Biochemical changes and morphological alterations of the liver in guinea-pigs after administration of simvastatin (HMG CoA reductase-inhibitor). PubMed: Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination therapy. PubMed: Prescribed use of cholesterol-lowering drugs in the United States, 1978 through 1988. PubMed: Toxicity of the HMG-coenzyme A reductase inhibitor, lovastatin, to rabbits. PubMed: Effects of lovastatin and leupeptin on ceroidogenesis of vitamin E-deficient and -supplemented young rats. PubMed: Lovastatin is hypertriglyceridemic in Syrian golden hamsters. PubMed: Treatment of hyperlipidemia reduces glomerular injury in obese Zucker rats. PubMed: The effect of cholestyramine and Mevinolin on the diurnal cycle of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase. PubMed: Hypolipidemic effects of CS-500 (ML-236B) in WHHL-rabbit, a heritable animal model for hyperlipidemia.