ferulic acid

2-propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-

CAS: 1135-24-6 C10 H10 O4 MW: 194.18650000

Identification

Nameferulic acid
IUPAC3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
CAS Number1135-24-6
EINECS214-490-0
FDA UNIIAVM951ZWST
Molecular FormulaC10 H10 O4
Molecular Weight194.18650000
MDL NumberMFCD00004400
Beilstein1570363
CoE Number10113
XlogP31.50 (est)

Regulatory

DG SANTE Food Flavourings08.089 4-hydroxy-3-methoxycinnamic acid

Physical Properties

Appearance pale yellow to tan powder (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 171.00 °C. @ 760.00 mm Hg
Boiling Point 439.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.000003 mmHg @ 25.00 °C. (est)
Flash Point 302.00 °F. TCC ( 150.00 °C. )
logP (o/w) 1.510
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantimicrobial agents

No sensory data available

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityintraperitoneal-mouse LD > 350 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryfood additive and cosmetic agents
Recommendation for ferulic acid usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)0.097 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)3200 (μg/person/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
Dairy products, excluding products of category 02.0 (01.0)3.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)2.00000
Edible ices, including sherbet and sorbet (03.0)3.00000
Processed fruit (04.1)2.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)10.00000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)5.00000
Bakery wares (07.0)10.00000
Meat and meat products, including poultry and game (08.0)2.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)2.00000
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)5.00000
Foodstuffs intended for particular nutritional uses (13.0)10.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)3.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)10.00000
Ready-to-eat savouries (15.0)15.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)5.00000

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Jiangyin Healthway International Trade Co., Ltd

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M&U International LLC

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O'Laughlin Industries Inc.

Manufacturer of chemicals and ingredients used in flavors, fragrances, food, beverages and cosmetics

Leading the Flavor and Fragrance Industry since 1980.

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Penta International Corporation

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Vigon International

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Potential Uses

antimicrobial agents

Natural Occurrence

almond plant apple fruit asparagus raw asparagus - 35 mg/kg bamboo moso bamboo barley seed bean black bean plant bean fava bean plant beer - up to 2 mg/kg PMC beet beet leaf bilberry fruit bilberry fruit juice bilberry leaf blueberry plant broccoli asparagus broccoli leaf brussel sprout leaf cabbage leaf cacao bean cantaloupe plant carob bean carrot root cayenne fruit celery root chamomile garden chamomile plant cherry sour cherry plant chicory leaf chive leaf coconut leaf coriander plant corn leaf corn seed corn sprout cranberry fruit cucumber fruit currant black currant fruit - up to 19 mg/kg dandelion flower date palm stem dill seed eggplant root elder black elder plant evening-primrose plant fennel seed fig plant flax seed garlic bulb ginger plant gooseberry fruit goosefoot fruit grape fruit hyssop plant leek wild leek plant lemon fruit lentil plant lettuce plant lovage fruit mandarin pericarp oat seed olive fruit onion bulb onion leaf onion root orange fruit orange fruit juice orange pericarp pea seed peach plant peanut nut pineapple plant plum fruit pomegranate fruit poppy opium poppy pericarp potato tuber purslane plant quince fruit radish root raspberry red raspberry fruit raspberry red raspberry plant rhubarb plant rhubarb root rice rice plant sage plant sesame fruit sesame leaf soybean - up to 0.1 mg/kg soybean plant soybean seed soybean shoot spinach indian spinach plant spinach inflorescence spinach leaf spirits - up to 0.4 mg/kg sunflower pollen tarragon leaf thyme plant tomato fruit walnut black walnut nut walnut english walnut nut walnut english walnut testa wheat seed wine - up to 12 mg/kg

Synonyms

coniferic acid 4- hydroxy-3-methoxy cinnammic acid 4- hydroxy-3-methoxycinnamic acid 3-(4- hydroxy-3-methoxyphenyl) acrylic acid 3-(4- hydroxy-3-methoxyphenyl)-2-propenoic acid 3-(4- hydroxy-3-methoxyphenyl)acrylic acid 3-(4- hydroxy-3-methoxyphenyl)prop-2-enoic acid 3- methoxy-4-hydroxycinnamic acid 2- propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)- PubMed: A Coenzyme-Independent Decarboxylase/Oxygenase Cascade for the Efficient Synthesis of Vanillin. PubMed: Single nucleotide polymorphisms of PAD1 and FDC1 show a positive relationship with ferulic acid decarboxylation ability among industrial yeasts used in alcoholic beverage production. PubMed: Transformation of ferulic acid to vanillin using a fed-batch solid-liquid two-phase partitioning bioreactor. PubMed: Breaking down lignin to high-value chemicals: the conversion of lignocellulose to vanillin in a gene deletion mutant of Rhodococcus jostii RHA1. PubMed: Characterization of two Streptomyces enzymes that convert ferulic acid to vanillin. PubMed: Biological activity and fatty acid composition of Caesar's mushroom. PubMed: Oxidative metabolites of curcumin poison human type II topoisomerases. PubMed: Influence of endogenous ferulic acid in whole wheat flour on bread crust aroma. PubMed: Studies on the key aroma compounds in soy milk made from three different soybean cultivars. PubMed: Efficient synthesis of hydroxystyrenes via biocatalytic decarboxylation/deacetylation of substituted cinnamic acids by newly isolated Pantoea agglomerans strains. PubMed: Effect of modification of the kilning regimen on levels of free ferulic acid and antioxidant activity in malt. PubMed: Microbial production of biovanillin. PubMed: Variability in the release of free and bound hydroxycinnamic acids from diverse malted barley (Hordeum vulgare L.) cultivars during wort production. PubMed: Effect of heat treatment on the antioxidant activity, color, and free phenolic acid profile of malt. PubMed: Production of a chimeric enzyme tool associating the Trichoderma reesei swollenin with the Aspergillus niger feruloyl esterase A for release of ferulic acid. PubMed: Bioconversions of ferulic acid, an hydroxycinnamic acid. PubMed: Antioxidant properties of kilned and roasted malts. PubMed: Biotransformation and impact of ferulic acid on phenylpropanoid and capsaicin levels in Capsicum annuum L. cv. P1482 cell suspension cultures. PubMed: Evaluation of antioxidant capacity of cereal brans. PubMed: Ferulic acid release and 4-vinylguaiacol formation during brewing and fermentation: indications for feruloyl esterase activity in Saccharomyces cerevisiae. PubMed: Biotransformations of propenylbenzenes by an Arthrobacter sp. and its t-anethole blocked mutants. PubMed: Real-time monitoring of 4-vinylguaiacol, guaiacol, and phenol during coffee roasting by resonant laser ionization time-of-flight mass spectrometry. PubMed: Effect of kilning on the antioxidant and pro-oxidant activities of pale malts. PubMed: Modification of the levels of polyphenols in wort and beer by addition of hexamethylenetetramine or sulfite during mashing. PubMed: Biotechnological production of vanillin.