sciadopitysin
amentoflavone-4',4''',7''-trimethylether
Identification
| Name | sciadopitysin |
| IUPAC | 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)chromen-4-one |
| CAS Number | 521-34-6 |
| EINECS | 208-311-5 |
| FDA UNII | WL44VY201L |
| Molecular Formula | C33 H24 O10 |
| Molecular Weight | 580.54628000 |
| MDL Number | MFCD00017448 |
| Nikkaji Number | J92.489J |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 839.60 °C. @ 760.00 mm Hg (est) |
| Flash Point | 529.00 °F. TCC ( 276.20 °C. ) (est) |
| logP (o/w) | 5.500 (est) |
| Soluble in | water, 0.0006502 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for sciadopitysin usage levels up to | not for fragrance use. |
| Recommendation for sciadopitysin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
amentoflavone-4',4''',7''-trimethylether
amentoflavone-4',4",7-trimethyl ether
amentoflavone-7,4',4'''-trimethyl ether
5,7-
dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1- benzopyran-2-yl)-2-methoxyphenyl)-2-(4-methoxyphenyl)-4- benzopyrone
5,7-
dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-methoxyphenyl)-4-benzopyrone
5,7-
dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-4-benzopyrone
5,7-
dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-4H-chromen-4-one
5,7-
dihydroxy-8-[5-(5-hydroxy-7-méthoxy-4-oxo-4H-chromén-2-yl)-2-méthoxyphényl]-2-(4-méthoxyphényl)-4H-chromén-4-one
5,7-
dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)chromen-4-one
PubMed:
Sciadopitysin alleviates methylglyoxal-mediated glycation in osteoblastic MC3T3-E1 cells by enhancing glyoxalase system and mitochondrial biogenesis.
PubMed:
Sciadopitysin: active component from Taxus chinensis for anti-Alzheimer's disease.
PubMed:
Sciadopitysin protects osteoblast function via its antioxidant activity in MC3T3-E1 cells.
PubMed:
Two new nonacosanetriols from Ginkgo biloba sarcotesta.
PubMed:
[Structrue identification of biflavones and determination of Taxol from Taxus Madia].
PubMed:
[Non-taxoid chemical constituents from leaves of Taxus mairei].
PubMed:
New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes.
PubMed:
In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids from Gingko biloba yellow leaves.
PubMed:
Biflavonoids inhibited phosphatase of regenerating liver-3 (PRL-3).
PubMed:
Osteoblast differentiation stimulating activity of biflavonoids from Cephalotaxus koreana.
PubMed:
Inhibition of cGMP-phosphodiesterase-5 by biflavones of Ginkgo biloba.
PubMed:
Biflavones from Chamaecyparis obtusa.
PubMed:
Chemical constituents from Amentotaxus yunnanensis and Torreyayunnanensis.
PubMed:
Antifungal activity of biflavones from Taxus baccata and Ginkgo biloba.
PubMed:
Biflavones of Ginkgo biloba stimulate lipolysis in 3T3-L1 adipocytes.
PubMed:
Effect of biflavones of Ginkgo biloba against UVB-induced cytotoxicity in vitro.
PubMed:
Inhibition of cAMP-phosphodiesterase by biflavones of Ginkgo biloba in rat adipose tissue.
PubMed:
[HPLC determination of six flavonoid constituents in Ginkgo biloba leaves].
PubMed:
Effects of flavonoids of Ginkgo biloba on proliferation of human skin fibroblast.
PubMed:
Suppression of mouse lymphocyte proliferation in vitro by naturally-occurring biflavonoids.
PubMed:
Flavonoid-induced acute nephropathy.
PubMed:
Inhibition of human non-pancreatic phospholipases A2 by retinoids and flavonoids. Mechanism of action.
PubMed:
Flavone modulators of rat hepatic aryl hydrocarbon hydroxylase.
PubMed:
HPLC Separation and Quantitative Determination of Biflavones in Leaves from Ginkgo biloba.