acrolein dimer

3,4-dihydro-2H-pyran-2-carbaldehyde

CAS: 100-73-2 C6 H8 O2 MW: 112.12816000

Identification

Nameacrolein dimer
IUPAC3,4-dihydro-2H-pyran-2-carbaldehyde
CAS Number100-73-2
EINECS202-884-5
FDA UNII49SA3RBS5H
Molecular FormulaC6 H8 O2
Molecular Weight112.12816000
MDL NumberMFCD00059170
Nikkaji NumberJ21.552J
Beilstein0107244

Regulatory

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 185.00 to 186.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.708000 mmHg @ 25.00 °C. (est)
Flash Point 164.00 °F. TCC ( 73.40 °C. ) (est)
logP (o/w) -0.388 (est)
Soluble in alcohol

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-rat LD50 4920 mg/kg
Dermal ToxicityNot determined
Inhalation Toxicityinhalation-rat LC50 3225 ppm/4H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for acrolein dimer usage levels up tonot for fragrance use.
Recommendation for acrolein dimer flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

odor neutralizer

Natural Occurrence

not found in nature

Synonyms

3,4- dihydro-(2H)-pyrane-2-carbaldehyde 2,3- dihydro-1,4-pyran-2-karboxaldehyd 3,4- dihydro-2H-pyran-2-carbaldehyde 3,4- dihydro-2H-pyran-2-carboxaldehyde 2- formyl-3,4-dihydro-2H-pyran 5- hexenal, 2,6-epoxy- 2- propenal dimer pyran aldehyde 2H- pyran-2-carboxaldehyde, 3,4-dihydro- a- tolyl aldehyde dimethyl acetal a- tolylaldehyde dimethyl acetal Google Patents: Acrolein dimer production PubMed: Lewis Acid-Catalyzed Synthesis of Benzofurans and 4,5,6,7-Tetrahydrobenzofurans from Acrolein Dimer and 1,3-Dicarbonyl Compounds PubMed: Gut Microbial Glycerol Metabolism as an Endogenous Acrolein Source PubMed: Acrolein in wine: importance of 3-hydroxypropionaldehyde and derivatives in production and detection PubMed: Robinetinidol-(4beta-->8)-epigallocatechin 3-O-gallate, a galloyl dimer prorobinetinidin from Acacia mearnsii De Wild, effectively protects human neuroblastoma SH-SY5Y cells against a PubMed: Decontamination of Minimally-Processed Fresh Lettuce Using Reuterin Produced by Lactobacillus reuteri PubMed: Hydralazine inhibits rapid acrolein-induced protein oligomerization: role of aldehyde scavenging and adduct trapping in cross-link blocking and cytoprotection PubMed: Reference Energies for Double Excitations PubMed: Acrolein with an alpha, beta-unsaturated carbonyl group inhibits LPS-induced homodimerization of toll-like receptor 4 PubMed: Chemoprotectants for cancer chemotherapy PubMed: Activation of Nrf2 attenuates delayed gastric emptying in obesity induced diabetic (T2DM) female mice PubMed: Cinnamaldehyde disrupts biofilm formation and swarming motility of Pseudomonas aeruginosa PubMed: To Be or Not to Be: Demystifying the 2nd-Quantized Picture of Complex Electronic Configuration Patterns in Chemistry with Natural Poly-Electron Population Analysis PubMed: 3-hydroxypropionaldehyde: applications and perspectives of biotechnological production PubMed: Effect of spermine-derived AGEs on oxidative stress and polyamine metabolism PubMed: New insights into the half-of-the-sites reactivity of human aldehyde dehydrogenase 1A1 PubMed: Semi-grand canonical Monte Carlo simulation of the acrolein induced surface segregation and aggregation of AgPd with machine learning surrogate models PubMed: Degradation and polymerization of monolignols by Abortiporus biennis, and induction of its degradation with a reducing agent PubMed: Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on tau aggregation and filament formation PubMed: Autocatalysis and organocatalysis with synthetic structures PubMed: Nature and strength of C-HúúúO interactions involving formyl hydrogen atoms: computational and experimental studies of small aldehydes PubMed: Synthesis and structural characterization of oaklin-catechins PubMed: Ifosfamide and mesna: effects on the Na/H exchanger activity in renal epithelial cells in culture (LLC-PK1) PubMed: Direct exposure of non-equilibrium atmospheric pressure plasma confers simultaneous oxidative and ultraviolet modifications in biomolecules PubMed: Initiation of repair of DNA-polypeptide cross-links by the UvrABC nuclease PubMed: Structure of polymeric polyphenols of cinnamon bark deduced from condensation products of cinnamaldehyde with catechin and procyanidins PubMed: Quantitation of formaldehyde, acetaldehyde, and acetone in sidestream cigarette smoke by high-performance liquid chromatography PubMed: Synthesis and biological evaluation of dimeric cinnamaldehydes as potent antitumor agents PubMed: Initial steps of the peroxidase-catalyzed polymerization of coniferyl alcohol and/or sinapyl aldehyde: capillary zone electrophoresis study of pH effect PubMed: Dithio-bis-mercaptoethanesulphonate (DIMESNA) does not prevent cellular damage by metabolites of ifosfamide and cyclophosphamide in LLC-PK1 cells PubMed: Tetramethylammonium hydroxide (TMAH) thermochemolysis of lignin: behavior of 4-O-etherified cinnamyl alcohols and aldehydes PubMed: Purification and characterization of a novel lignin peroxidase from white-rot fungus Phanerochaete sordida YK-624 PubMed: Solvent Effects on Electronically Excited States Using the Conductor-Like Screening Model and the Second-Order Correlated Method ADC(2) PubMed: Reaction of tobacco smoke aldehydes with human hemoglobin PubMed: Synthesis of nonracemic allylic hydroxy phosphonates via alkene cross metathesis PubMed: Arene-ruthenium complexes with salicyloxazolines: diastereoselective synthesis, configurational stability and applications as asymmetric catalysts for Diels-Alder reactions PubMed: A new class of synthetic biological response modifiers: the methylfurylbutyrolactones (Nafocare B) PubMed: Enhanced pi ... pi interactions in alpha,beta-unsaturated carbonyls PubMed: Interaction of cyclophosphamide metabolites with membrane proteins: an in vitro study with rabbit liver microsomes and human red blood cells. Effect of thiols PubMed: Non-adiabatic intramolecular and photodissociation dynamics studied by femtosecond time-resolved photoelectron and coincidence imaging spectroscopy PubMed: Two stable Fenton oxidation products of cyclophosphamide (NSC-26271) as precursors of 4-hydroxycyclophosphamide (NSC-196562) under physiologic conditions PubMed: Biologic activity of two derivatives and six possible metabolites of cyclophosphamide (NSC-26271) PubMed: [Mechanism of thermal denaturation of native trypsin and trypsin modified by neutral soluble polymer]